Efficacy of a small dose of oral dexamethasone in croup

Biomedical Research

Volumn 16, Issue 1, 2005, Pages 65-72

  Alshehri, Mohammed ^a   Almegamsi, Talal ^b   Hammdi, Anwar ^c  

^a KING KHALID UNIVERSITY   (Saudi Arabia)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^c KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

Acute laryngotracheobronchitis; Children; Croup score; Dexamethasone

Indexed keywords

ADRENALIN; DEXAMETHASONE;

ARTICLE; BREATHING DISORDER; CHILD; CHILDHOOD DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; CROUP; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FEVER; HOSPITALIZATION; HUMAN; INFANT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; STRIDOR; TREATMENT OUTCOME;

EID: 16244395138     PISSN: 0970938X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Denny FW, Murphy TF, Clyde WA Jnr, et al Croup: an 11-year study in a pediatric practice. Pediatrics 1983; 71: 871-876.
2. Skolnik NS. Treatment of croup: a critical review. Am J Dis Child 1989; 143: 1045-1049.
3. Waisman Y, Klein BL, Boenning DA, et al Prospective randomised double-blind study comparing L-epinephrine and racemic epinephrine aerosols in the treatment of laryngotracheitis (croup). Pediatrics 1992; 89: 302-306.
4. Epinephrine aerosols in the treatment of laryngotracheitis (croup). Pediatrics 1992; 89: 302-306.
5. Westley CR, Cotton EK, Brooks JG. Nebulized racemic epinephrine by IPPB for the treatment of croup: a double-blind study. Am J Dis Child 1978; 132: 484-487.
6. Novik, A. Corticosteroid treatment of non-diphtheritic croup. Acta Otolaryngol 1960; 158: 20-23.
7. Martensson, B., Nilson, G., & Torbjar, J. The effect of corticosteroids in the treatment of pseudo-croup. Acta Otolaryngol 1960; 158: 62-71.
8. James JA. Dexamethasone in croup: a controlled study. Am J Dis Child 1969; 117: 511-516.
9. Leipzig B, Oski FA, Cummings CW, Stockman JA, Swender P. A prospective randomized study to determine the efficacy of steroids in the treatment of croup. J Pediatr 1979; 94: 194-196.
10. Muhlendahl KE v, Kahn D, Spohr HL, Dressler F. Steroid treatment in pseudo-croup. Helvetica Paediatrica Acta 1982; 37: 431-436.
11. Sussman S, Grossman M, Magoffin R, Schieble J. Dexamethasone (16 alpha-methyl, 9 alphafluoroprednisolone) in obstructive respiratory tract infections in children: a controlled study. Pediatrics 1964; 34: 851-855.
12. Eden AN, Larkin VP. Corticosteroid treatment of croup. Pediatrics 1964; 33: 768-769.
13. Skowron PN, Turner JA, McNaughton GA. The use of corticosteroid (dexamethasone) in the treatment of acute laryngotracheitis. Can Med Assoc J 1966; 94: 528-53.
14. Eden AN, Kaufman A, Yu R. Corticosteroids and croup: controlled double-blind study. JAMA 1967; 200: 403-404.
15. Koren G, Frand M, Barzilay Z, MacLeod SM. Corticosteroid treatment of laryngotracheitis vs. spasmodic croup in children. Am J Dis Child 1983; 137: 941-944.
16. Tunnessen WW, Feinstein AR. The steroid-croup controversy: an analytical review of methodological problems. J Pediatr 1980; 96: 751-756.
17. Super DM, Cartelli NA, Brooks U, Lembo RM, Kumar ML. A prospective randomized double-blind study to evaluate the effect of dexamethasone in acute laryngotracheitis. J Pediatr 1989; 115: 323-329.
18. Kuuseia AL, Vesikari T. A randomized double-blind, placebo-controlled trial of dexamethasone and racemic epinephrine in the treatment of croup. Acta Paediatr Scand 1988; 77: 99-1 04.
19. Tibballs J, Shann FA, Landau LI. Placebo-controlled trial of prednisolone in children intubated for croup. Lancet 1992; 340: 745-748.
20. Husby 5, Agertoft L, Mortensen 5, Pedersen S. Treatment of croup with nebulised steroid (budesonide): a double blind, placebo controlled study. Arch Dis Child 1993; 68: 352-355.
21. Geeihoed GC, Macdonald WB. Oral and inhaled steroids in croup: a randomized, placebo-controlled trial. Pediatr Pulmonol 1995; 20: 355-361.
22. Kastrup EK, Olan B III, eds. Drug facts and comparisons. St. Louis: JB Lippincott, 1988: 346.
23. Yates RW, Doull IJ. A risk-benefit assessment of corticosteroids in the management of croup. Drug Saf 1997; 16: 48-55.
24. Johnson DW, Schch 5, Koren G, Jaffe DM. Outpatient treatment of croup with nebulized "dexamethasone. Arch Pediatr Adolesc Med 1996; 150: 349-355.
25. Brown GW. Counts, scales, scores: Levels of observation. Am J Dis Child 1985; 139: 147-151.
26. Smith DS. Corticosteroids in croup: a chink in the ivory tower? J Pediatr 1989; 115: 256-257.
27. Welliver RC, Wong DT, Middeton E, Sun M, McCarthy N, Ogra PL. Role of parainflunza virus-specific IgE in pathogensis of croup and wheezing subsequently to infection. J Pediatr 1982; 101: 889-896.
28. Loughlin GM, Taussig LM. Pulmonary function in children with a history of laryngotracheobronchitis. J Pediatr 1979; 94: 365-369.
29. Zach M, Erben A, Olinsky A. Croup, recurrent croup, allergy and airways hyperreactivity. Arch Dis Child 1981; 56: 336-341
30. Corkey CWB, Barker GA, Edmonds JF, Mok PM, Newth CJL. Radiographic tracheal diameter measurements in acute infectious croup: An objective scoring system. Crit Care Med 1981; 9: 587-590.
31. To, T. & Young, W. Hospitalizations for croup in Ontario [abstract]. Clin Invest Med 1994; 17: A25.
32. Marx, A, Torok, TJ. Holman, RC., & Clarke, MJ. Pediatric hospitalizations for croup (laryngotracheitis): biennal increases associated with human parainfluenza virus 1 epidemics. J Infect Dis 1997; 176: 1423-1427.
33. Johnson DW, Jacobson 5, Edney PC, Hadfield P, Mundy ME, Schuh S. A comparison of nebulized budesonide, intramuscular dexamethasone, and placebo for moderately severe croup. N Engl J Med 1998; 339: 498-503.
34. Geelhoed GC, Turner J, Macdonald WBG. Efficacy of a small single dose of oral dexamethasone for outpatient's croup: a double blind placebo controlled clinical trial. BMJ 1996; 313: 140-142.
35. Kairys SW, Olmstead EM, O'Connor GT. Steroid treatment of laryngotracheitis: a meta-analysis of the evidence from randomized trials. Pediatrics 1989; 83: 683-693.
36. Klassen TP, Feldman ME, Watters LK, Sutcliffe T, Rowe PC. Nebulized budesonide for children with mild to moderate croup. N Engl J Med 1994; 331: 285-289. [Abstract/Free Full Text]
37. Zach MS, Schnall RP, Landau LI. Upper and lower airway hyperreactivity in recurrent croup. Am Rev Respir Dis 1980; 121: 979-983.
38. Henrickson KJ, Kuhn SM, Savatski LU. Epidemiology and cost of infection with human parainfluenza virus types 1 and 2 in young children. Clin Infect Dis 1997; 18: 770-779.
39. Kumar M, Super D, Lembo R, Thomas F, Prokay S. Efficacies of two rapid respiratory syncytial virus diagnostic tests. J Clin Microbial 1987; 25: 873-875.
40. Lennette EH. Diagnostic procedures for viral, rickettsial and chlamydial infections. Washington D.C.: American Public Health Association, 1979.