Crystal structures of proto-oncogene kinase Pim1: A target of aberrant somatic hypermutations in diffuse large cell lymphoma

Journal of Molecular Biology

Volumn 348, Issue 1, 2005, Pages 183-193

  Kumar, Abhinav ^a   Mandiyan, Valsan ^a,b   Suzuki, Yoshihisa ^a   Zhang, Chao ^a   Rice, Julie ^a   Tsai, James ^a   Artis, Dean R ^a   Ibrahim, Prabha ^a   Bremer, Ryan ^a  

^a PLEXXIKON INC   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Crystal structure; Kinase; Pim1; Scaffold discovery; Somatic hypermutation

Indexed keywords

ADENINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; METHIONINE; ONCOPROTEIN; PHOSPHOTRANSFERASE INHIBITOR; PROLINE; PROTEIN KINASE PIM 1; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; HUMAN; HYDROGEN BOND; LARGE CELL LYMPHOMA; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; SOMATIC HYPERMUTATION; STRUCTURE ANALYSIS;

EID: 16244377514     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.02.039     Document Type: Article

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