Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11

British Journal of Cancer

Volumn 92, Issue 5, 2005, Pages 882-887

  Oosterhoff, D ^a   Overmeer, R M ^a   De Graaf, M ^a   Van Der Meulen, I H ^a   Giaccone, G ^a   Van Beusechem, V W ^a   Haisma, H J ^b   Pinedo, H M ^a   Gerritsen, W R ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Adenovirus; Carboxylesterase; CPT 11; EpCAM; Spheroid

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ADENOVIRUS VECTOR; CARBOXYLESTERASE; COMPLEMENTARY DNA; EPITHELIAL CELL ADHESION MOLECULE; IRINOTECAN;

ARTICLE; CANCER CELL CULTURE; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ASSAY; GENE DIRECTED ENZYME PRODRUG THERAPY; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; SPHEROID CELL; WESTERN BLOTTING;

ADENOVIRIDAE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CARBOXYLESTERASE; CELL LINE, TUMOR; CELL SURVIVAL; COLONIC NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; HUMANS; OVARIAN NEOPLASMS;

EID: 16244373666     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602362     Document Type: Article

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