Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT

Brain Research Bulletin

Volumn 65, Issue 3, 2005, Pages 241-247

  Mussi, P ^a   Ciana, P ^a   Raviscioni, M ^a   Villa, R ^b   Regondi, S ^a   Agradi, E ^a   Maggi, A ^a   Di Lorenzo, D ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Contaminants; Endocrine disruptors; Hormones; Metabolism; Nervous system; Transgenic mouse

Indexed keywords

BRAIN RECEPTOR; CHLORPHENOTANE; ESTRADIOL; ESTROGEN RECEPTOR; LUCIFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BIOENGINEERING; BREAST CANCER; CANCER CELL CULTURE; CONFERENCE PAPER; CONTROLLED STUDY; EXPERIMENT; EXPERIMENTAL MODEL; EXPOSURE; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; KINETICS; LACTATION; LIVER; LIVER MICROSOME; METABOLISM; MILK; MOTHER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCTION; TISSUE; TRANSGENIC MOUSE;

EID: 16244373403     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2004.11.016     Document Type: Conference Paper

References (35)

1. W.W. Beatty Gonadal hormones and sex differences in non reproductive behaviors in rodents: organizational and activational influences Horm. Behav. 12 1979 112 163
2. M.M. Bradford A rapid and sensitive method for the quantification of microgram quantities of proteins utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
3. A.M. Brzozowski, A.C. Pike, Z. Dauter, R.E. Hubbard, T. Bonn, O. Engstrom, L. Ohman, G.L. Greene, J.A. Gustafsson, and M. Carlquist Molecular basis of agonism and antagonism in the oestrogen receptor Nature 389 1997 753 758
4. M.D. Burke, and R.T. Mayer Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealchilation which is preferentially inducible by 3-methylcholantrene Drug Metab. Disp. 2 1974 583 588
5. C.W. Chen, C. Hurd, D.P. Vorojeikina, S.F. Arnold, and A.C. Notides Trascriptional activation of the human estrogen receptor by DDT isomers and metabolites in yeast and MCF-7 cells Biochem. Pharmacol. 53 1997 1161 1172
6. P. Ciana, G. Di Luccio, S. Belcredito, G. Pollio, E. Vegeto, L. Tatangelo, C. Tiveron, and A. Maggi Engineering of a mouse for the in vivo profiling of estrogen receptor activity Mol. Endocrinol. 15 2001 1104 1113
7. P. Ciana, M. Raviscioni, P. Mussi, E. Vegeto, I. Que, M.G. Parker, C. Lowik, and A. Maggi In vivo imaging of transcriptionally active estrogen receptors Nat. Med. 9 2003 82 86
8. T. Colborn, F.S. vom Saal, and A.M. Soto Developmental effects of endocrine-disrupting chemicals in wildlife and humans Environ. Health Perspect. 101 1993 378 384
9. A. Curley, M.F. Copeland, and R.D. Kimbrough Chlorinated hydrocarbon insecticides in organs of stillborn and blood of newborn babies Arch. Environ. Health 19 1969 628 632
10. J.R. de Wet, K.V. Wood, M. DeLuca, D.R. Helinski, and S. Subramani Firefly luciferase gene: structure and expression in mammalian cells Mol. Cell. Biol. 7 1987 725 737
11. D. Di Lorenzo, R. Villa, G. Biasiotto, S. Belloli, G. Ruggeri, A. Albertini, P. Apostoli, M. Raviscioni, P. Ciana, and A. Maggi Isomer-specific activity of dichlorodiphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice Endocrinology 143 2002 4544 4551
12. G. Dorner, and A. Plagemann DDT in human milk and mental capacities in children at school age: an additional view on PISA Neuroendocrinol. Lett. 23 2002 427 431
13. P. Eriksson, J. Ahlbom, and A. Fredriksson Exposure to DDT during a defined period in neonatal life induces permanent changes in brain muscarinic receptors and behaviour in adult mice Brain Res. 582 1992 277 281
14. P. Eriksson, and U. Talts Neonatal exposure to neurotoxic pesticides increases adult susceptibility: a review of current findings Neurotoxicology 21 2000 37 47
15. E.G. Esaac, and F. Matsumura Metabolism of insecticides by reductive systems Pharmacol. Ther. 9 1980 1 26
16. S.D. Fox, J.M. Roman, H.J. Issaq, and R.W. Nims Metabolic conversion of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD) to 1,1-dichloro-2,2-bis(p- chlorophenyl)ethylene (DDE) in the male F344/NCr rat Arch. Environ. Contam. Toxicol. 35 1998 104 108
17. D.E. Frigo, M.E. Burow, K.A. Mitchell, T.C. Chiang, and J.A. McLachlan DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms Environ. Health Perspect. 110 2002 1239 1245
18. R.J. Gellert, W.L. Heinrichs, and R.S. Swerdloff DDT homologues: estrogen-like effects on the vagina, uterus and pituitary of the rat Endocrinology 91 1972 1095 1100
19. K.A. Hassall, and T.J. Forrest Reductive dechlorination of DDT by heated liver Nat. New Biol. 236 1972 214 246
20. J.A. Katzenellenbogen, B.W. O'Malley, and B.S. Katzenellenbogen Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones Mol. Endocrinol. 10 1996 119 131
21. W.R. Kelce, C.R. Stone, S.C. Laws, L.E. Gray, J.A. Kemppainen, and E.M. Wilson Persistent DDT metabolite p,p′-DDE is a potent androgen receptor antagonist Nature 375 1995 581 585
22. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
23. A. Matsumoto Synaptogenic action of sex steroids in developing and adult neuroendocrine brain Psychoneuroendocrinology 16 1991 25 40
24. B.S. McEwen Steroid hormones: effect on brain development and function Horm. Res. 37 1992 1 10
25. P. Palanza, F. Morellini, S. Parmigiani, and F.S. vom Saal Prenatal exposure to endocrine disrupting chemicals: effects on behavioral development Neurosci. Biobehav. Rev. 23 1999 1011 1027
26. G.E. Quinby, J.F. Armstrong, and W.F. Durham DDT in human milk Nature 207 1965 726 728
27. J.F. Savouret, A. Bailly, M. Misrahi, C. Rauch, G. Redeuilh, A. Chauchereau, and E. Milgrom Characterization of the hormone responsive element involved in the regulation of the progesterone receptor gene EMBO J. 10 1991 1875 1883
28. G. Scatchard The attraction of proteins for small molecules and ions Ann. N.Y. Acad. Sci. 51 1947 660 668
29. N. Shinomiya, and M. Shinomiya Dichlorodiphenyltrichloroethane suppresses neurite outgrowth and induces apoptosis in PC12 pheochromocytoma cells Toxicol. Lett. 137 2003 175 183
30. M.A. Shupnik, M.S. Gordon, and W.W. Chin Tissue-specific regulation of rat estrogen receptor mRNAs Mol. Endocrinol. 3 1989 660 665
31. D.W. Singleton, and S.A. Khan Xenoestrogen exposure and mechanisms of endocrine disruption Front. Biosci. 8 2003 110 118
32. J.J. Stegeman, and R.L. Binder High benzo[a]pyrene hydoxylase activity in the marine fish Stenotomus versicolor Biochem. Pharmacol. 28 1979 1686 1688
33. B. van Wendel de Joode, C. Wesseling, H. Kromhout, P. Monge, M. Garcia, and D. Mergler Chronic nervous-system effects of long-term occupational exposure to DDT Lancet 357 2001 1014 1016
34. S.M. Waliszewski, A.A. Aguirre, R.M. Infanzon, C.S. Silva, and J. Siliceo Organochlorine pesticide levels in maternal adipose tissue, maternal blood serum, umbilical blood serum, and milk from inhabitants of Veracruz Mexico, Arch. Environ. Contam. Toxicol. 40 2001 432 438
35. R.M. Welch, W. Levin, and A.H. Conney Estrogenic action of DDT and its analogs Toxicol. Appl. Pharmacol. 14 1969 358 367