The characteristics of quality of life impairment in adult growth hormone (GH)-deficient survivors of cancer and their response to GH replacement therapy

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 3, 2005, Pages 1542-1549

  Mukherjee, A ^a   Tolhurst Cleaver, S ^a   Ryder, W D J ^a   Smethurst, L ^a   Shalet, S M ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; HUMAN GROWTH HORMONE; SOMATOMEDIN C;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ANXIETY; ARTICLE; BODY MASS; CANCER DIAGNOSIS; CANCER SURVIVAL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DEPRESSION; FEMALE; FOLLOW UP; GENDER; GROWTH HORMONE DEFICIENCY; HEALTH; HORMONE SUBSTITUTION; HUMAN; HYPOPHYSIS DISEASE; LONG TERM CARE; MALE; MEDICAL ASSESSMENT; OUTCOMES RESEARCH; PATHOLOGY; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; QUALITY OF LIFE; SELF CONTROL; WELLBEING; ADENOMA; AGED; BRAIN TUMOR; CLINICAL TRIAL; COHORT ANALYSIS; HYPOPHYSIS TUMOR; METABOLISM; MIDDLE AGED; MORTALITY; PROLACTINOMA;

ADENOMA; ADOLESCENT; ADULT; AGED; BRAIN NEOPLASMS; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; PITUITARY NEOPLASMS; PROLACTINOMA; QUALITY OF LIFE;

EID: 15944402826     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-0832     Document Type: Article

References (39)

1. Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Mariotto A, Fay MP, Feuer EJ, Edwards BK 2003 SEER Cancer statistics review, 1975-2000. Bethesda: National Cancer Institute; http://seer.cancer.gov/csr/1975_2000
2. Johannesen TB, Langmark F, Lote K 2003 Progress in long-term survival in adult patients with supratentorial low-grade gliomas: a population-based study of 993 patients in whom tumors were diagnosed between 1970 and 1993. J Neurosurg 99:854-862
3. Johannesen TB, Langmark F, Lote K 2003 Cause of death and long-term survival in patients with neuro-epithelial brain tumours: a population-based study. Eur J Cancer 39:2355-2363
4. Shalet SM, Beardwell CG, Pearson D, Jones PH 1976 The effect of varying doses of cerebral irradiation on growth hormone production in childhood. Clin Endocrinol (Oxf) 5:287-290
5. Shalet SM 1983 Disorders of the endocrine system due to radiation and cytotoxic chemotherapy. Clin Endocrinol (Oxf) 19:637-659
6. Shalet SM, Clayton PE, Price DA 1988 Growth and pituitary function in children treated for brain tumours or acute lymphoblastic leukaemia. Horm Res 30:53-61
7. Brennan BM, Rahim A, Mackie EM, Eden OB, Shalet SM 1998 Growth hormone status in adults treated for acute lymphoblastic leukaemia in childhood. Clin Endocrinol (Oxf) 48:777-783
8. Almqvist O, Thoren M, Saaf M, Eriksson O 1986 Effects of growth hormone substitution on mental performance in adults with growth hormone deficiency: a pilot study. Psychoneuroendocrinology 11:347-352
9. McGauley GA 1989 Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency. Acta Paediatr Scand 356(Suppl):70-74
10. Rosen T, Wiren L, Wilhelmsen L, Wiklund I, Bengtsson BA 1994 Decreased psychological well-being in adult patients with growth hormone deficiency. Clin Endocrinol (Oxf) 40:111-116
11. Burman P, Broman JE, Hetta J, Wiklund I, Erfurth EM, Hagg E, Karlsson FA 1995 Quality of life in adults with growth hormone (GH) deficiency: response to treatment with recombinant human GH in a placebo-controlled 21-month trial. J Clin Endocrinol Metab 80:3585-3590
12. Wallymahmed ME, Baker GA, Humphris G, Dewey M, MacFarlane IA 1996 The development, reliability and validity of a disease specific quality of life model for adults with growth hormone deficiency. Clin Endocrinol (Oxf) 44:403-411
13. Lynch S, Merson S, Beshyah SA, Skinner E, Sharp P, Priest RG, Johnston DG 1994 Psychiatric morbidity in adults with hypopituitarism. J R Soc Med 87:445-447
14. Murray RD, Darzy KH, Gleeson HK, Shalet SM 2002 GH-deficient survivors of childhood cancer: GH replacement during adult life. J Clin Endocrinol Metab 87:129-135
15. Herold AH, Roetzheim RG 1992 Cancer survivors. Prim Care 19:779-791
16. Jenkin D, Danjoux C, Greenberg M 1998 Subsequent quality of life for children irradiated for a brain tumor before age four years. Med Pediatr Oncol 31:506-511
17. Barr RD, Simpson T, Whitton A, Rush B, Furlong W, Feeny DH 1999 Health-related quality of life in survivors of tumours of the central nervous system in childhood: a preference-based approach to measurement in a cross-sectional study. Eur J Cancer 35:248-255
18. Hudson MM, Mertens AC, Yasui Y, Hobbie W, Chen H, Gurney JG, Yeazel M, Recklitis CJ, Marina N, Robison LR, Oeffinger KC 2003 Health status of adult long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. JAMA 290:1583-1592
19. Dupuy HJ 1984 The psychological general well-being index. In: Wenger NK, Mattson ME, Furberg CD, Elinson U, eds. Assessment of quality of life in clinical trials of cardiovascular therapies. New York: Le Jacq; 170-183
20. McKenna SP, Doward LC, Alonso J, Kohlmann T, Niero M, Prieto L, Wirén L 1999 The QoL-AGHDA: an instrument for the assessment of quality of life in adults with growth hormone deficiency. Qual Life Res 4:373-383
21. Shalet SM, Toogood A, Rahim A, Brennan BM 1998 The diagnosis of growth hormone deficiency in children and adults. Endocr Rev 19:203-223
22. Pinheiro JC, Bates DM 2000 Mixed-effects models in S and S-PLUS. New York: Springer
23. 2000 S-PLUS 2000 Guide to statistics. Seattle: MathSoft
24. Drake WM, Coyte D, Camacho-Hubner C, Jivanji NM, Kaltsas G, Wood DF, Trainer PJ, Grossman AB, Besser GM, Monson JP 1998 Optimizing growth hormone replacement therapy by dose titration in hypopituitary adults. J Clin Endocrinol Metab 83:3913-3919
25. Murray RD, Skillkorn CJ, Howell SJ, Lissett CA, Rahim A, Shalet SM 1999 Dose titration and patient selection increases the efficacy of GH replacement in severely GH deficient adults. Clin Endocrinol (Oxf) 50:749-757
26. Baum HB, Katznelson L, Sherman JC, Biller BM, Hayden DL, Schoenfeld DA, Cannistraro KE, Klibanski A 1998 Effects of physiological growth hormone (GH) therapy on cognition and quality of life in patients with adult-onset GH deficiency. J Clin Endocrinol Metab 83:3184-3189
27. Chrisoulidou A, Kousta E, Beshyah SA, Robinson S, Johnston DG 1998 How much, and by what mechanisms, does growth hormone replacement improve the quality of life in GH-deficient adults? Baillieres Clin Endocrinol Metab 12:261-279
28. Murray RD, Skillicorn CJ, Howell SJ, Lissett CA, Rahim A, Smethurst LE, Shalet SM 1999 Influences on quality of life in GH deficient adults and their effect on response to treatment. Clin Endocrinol (Oxf) 51:565-573
29. Blum WF, Shavrikova EP, Edwards DJ, Rosilio M, Hartman ML, Marin F, Valle D, van der Lely AJ, Attanasio AF, Strasburger CJ, Henrich G, Herschbach P 2003 Decreased quality of life in adult patients with growth hormone deficiency compared with general populations using the new, validated, self-weighted questionnaire, questions on life satisfaction hypopituitarism module. J Clin Endocrinol Metab 88:4158-4167
30. Badia X, Lucas A, Sanmarti A, Roset M, Ulied A 1998 One-year follow-up of quality of life in adults with untreated growth hormone deficiency. Clin Endocrinol (Oxf) 49:765-771
31. Wiren L, Whalley D, McKenna S, Wilhelmsen L 2000 Application of a disease-specific, quality-of-life measure (QoL-AGHDA) in growth hormone-deficient adults and a random population sample in Sweden: validation of the measure by rasch analysis. Clin Endocrinol (Oxf) 52:143-152
32. Attanasio AF, Lamberts SW, Matranga AM, Birkett MA, Bates PC, Valk NK, Hilsted J, Bengtsson BA, Strasburger CJ 1997 Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment. Adult Growth Hormone Deficiency Study Group. J Clin Endocrinol Metab 82:82-88
33. Rikken B, van Busschbach J, le Cessie S, Manten W, Spermon T, Grobbee R, Wit JM 1995 Impaired social status of growth hormone deficient adults as compared to controls with short or normal stature. Dutch Growth Hormone Working Group. Clin Endocrinol (Oxf) 43:205-211
34. Johannsson G, Albertsson-Wikland K, Bengtsson BA 1999 Discontinuation of growth hormone (GH) treatment: metabolic effects in GH-deficient and GH-sufficient adolescent patients compared with control subjects. Swedish Study Group for Growth Hormone Treatment in Children. J Clin Endocrinol Metab 84:4516-4524
35. Vahl N, Juul A, Jorgensen JO, Orskov H, Skakkebaek NE, Christiansen JS 2000 Continuation of growth hormone (GH) replacement in GH-deficient patients during transition from childhood to adulthood: a two-year placebo-controlled study. J Clin Endocrinol Metab 85:1874-1881
36. Nonelund H, Vahl N, Juul A, Moller N, Alberti KG, Skakkebaek NE, Christiansen JS, Jorgensen JO 2000 Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism. J Clin Endocrinol Metab 85:1912-1917
37. Jorgensen JO, Norrelund H, Vahl N, Juul A, Skakkebaek NE, Christiansen JS 2002 Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function. J Pediatr Endocrinol Metab 15(Suppl 5):1355-1360
38. Shalet SM, Shavrikova E, Cromer M, Child CJ, Keller E, Zapletalova J, Moshang T, Blum WF, Chipman JJ, Quigley CA, Attanasio AF 2003 Effect of growth hormone (GH) treatment on bone in postpubertal GH-deficient patients: a 2-year randomized, controlled, dose-ranging study. J Clin Endocrinol Metab 88:4124-4129
39. Swerdlow AJ, Reddingius RE, Higgins CD, Spoudeas HA, Phipps K, Qiao Z, Ryder WD, Brada M, Hayward RD, Brook CG, Hindmarsh PC, Shalet SM 2000 Growth hormone treatment of children with brain tumors and risk of tumor recurrence. J Clin Endocrinol Metab 85:4444-4449