Untangling the effects of codon mutation and amino acid exchangeability

Proceedings of the Pacific Symposium on Biocomputing 2005, PSB 2005

Volumn , Issue , 2005, Pages 433-444

  Yampolsky, L Y ^a   Stoltzfus, A ^b  

^a EAST TENNESSEE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONVEX FUNCTIONS; DETAILED MODELS; EVOLUTIONARY CHANGES; GENETIC CODE; HUMAN PROTEINS; META-ANALYSIS; MISSENSE MUTANTS; MUTATION RATES; MUTATIONAL EFFECTS; NATURAL VARIATION; POPULATION VARIATION; PRIOR ESTIMATES; PROTEIN ACTIVITY; PROTEIN EVOLUTION; RELATIVE CONTRIBUTION; RELATIVE EFFECTS;

ALIGNMENT; AMINO ACIDS;

PROTEINS;

PROTEIN;

AMINO ACID SUBSTITUTION; ANALYSIS OF VARIANCE; ARTICLE; BIOLOGICAL MODEL; CHEMISTRY; CODON; GENETIC VARIABILITY; GENETICS; HUMAN; MISSENSE MUTATION; MUTATION; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SUBSTITUTION; ANALYSIS OF VARIANCE; CODON; HUMANS; MODELS, GENETIC; MUTATION; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; REPRODUCIBILITY OF RESULTS; VARIATION (GENETICS);

EID: 15944399071     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (18)

1. L. Y. Yampolsky, A. Stoltzfus, (in review).
2. I. Ebersberger, D. Metzler, C. Schwarz, S. Paabo, Am J Hum Genet 70, 1490-7 (Jun, 2002).
3. P. H. A. Sneath, Journal of Theoretical Biology 12, 157 (1966).
4. M. Krawczak, D. N. Cooper, Hum Mutat 8, 23-31 (1996).
5. Z. Yang, R. Nielsen, M. Hasegawa, Mol Biol Evol 15, 1600-11. (1998).
6. D. Vitkup, C. Sander, G. M. Church, Genome Biol 4, R72 (2003).
7. R. Grantham, Science 185, 862-864 (1974).
8. T. Miyata, S. Miyazawa, T. Yasunaga, J Mol Evol 12, 219-36 (Mar 15, 1979).
9. S. Henikoff, J. G. Henikoff, Proc Natl Acad Sci USA 89, 10915-9. (1992).
10. A. G. Clark et al, Science 302, 1960-3 (Dec 12, 2003).
11. D. Fredman et al, Nucleic Acids Res 30, 387-91 (Jan 1, 2002).
12. P. D. Stcnson et al., Hum Mutat 21, 577-81 (Jun, 2003).
13. Y. Nakamura, T. Gojobori, T. Ikemura, Nucleic Acids Res 28, 292 (Jan 1, 2000).
14. K. D. Pruitt, D. R. Maglott, Nucleic Acids Res 29, 137-40(Jan 1, 2001).
15. N. Goldman, Z. Yang, Mol Biol Evol 11, 725-36 (1994).
16. W. M. Fitch, J. Mol. Biol. 16, 9-16 (1966).
17. SASJnstitute, JMP ® Statistics and Graphis Guide (SAS Institute, Cary, NC, 2002).
18. J. F. Crow and M. Kimura. An Introduction to Population Genetics Theory. Burgess Publ., Minneapolis, 1970.