Large-scale purification of oligonucleotides by extraction and precipitation with butanole

Biotechnology and Bioengineering

Volumn 89, Issue 5, 2005, Pages 551-555

  Wolfrum, Christian ^a   Josten, Andre ^a   Bauer, Georg ^a   Götz, Peter ^b  

^a Identif GmbH   (Germany)

^b TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Butanole; Extraction; Large scale; Oligonucleotide; Precipitation; Purification

Indexed keywords

EXTRACTION; ORGANIC COMPOUNDS; PRECIPITATION (CHEMICAL); PURIFICATION; SYNTHESIS (CHEMICAL); THERMAL EFFECTS;

BUTANOLE; EXTRACTION LIQUID; OLIGONUCLEOTIDES; SYNTHESIZERS;

OLIGOMERS;

BUTANOL; NUCLEIC ACID; OLIGONUCLEOTIDE;

APPARATUS; ARTICLE; AUTOMATION; LARGE SCALE PRODUCTION; LIQUID LIQUID EXTRACTION; NUCLEOTIDE METABOLISM; PRECIPITATION; PROTEIN PURIFICATION; TEMPERATURE DEPENDENCE;

BUTANOLS; OLIGONUCLEOTIDES; PRECIPITATION;

EID: 15944395397     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20378     Document Type: Article

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