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Volumn 12, Issue 2, 2004, Pages 463-472

Mitochondrial DNA mutations in chemical carcinogen-induced rat bladder and human bladder cancer

Author keywords

Animal model; Bladder cancer; Mitochondrial DNA; Mutations

Indexed keywords

CARCINOGEN; DNA; MITOCHONDRIAL DNA; OXYGEN; PRIMER DNA;

EID: 15944392946     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.12.2.463     Document Type: Article
Times cited : (19)

References (72)
  • 1
    • 65149086980 scopus 로고    scopus 로고
    • 2nd edition. Shanghai Medical University Press, Shanghai
    • Tang CQ (ed): Modern Oncology (in Chinese). 2nd edition. Shanghai Medical University Press, Shanghai, pp10-17, 2000.
    • (2000) Modern Oncology (in Chinese) , pp. 10-17
    • Tang, C.Q.1
  • 2
    • 0031717333 scopus 로고    scopus 로고
    • Molecular alterations in bladder cancer
    • DOI 10.1007/s002400050050
    • Ørntoft TF and Wolf H: Molecular alterations in bladder cancer. Urol Res 26: 223-233, 1998. (Pubitemid 28416994)
    • (1998) Urological Research , vol.26 , Issue.4 , pp. 223-233
    • Orntoft, T.F.1    Wolf, H.2
  • 3
    • 0032822748 scopus 로고    scopus 로고
    • The genetics of transitional cell carcinoma: Progress and potential clinical application
    • DOI 10.1046/j.1464-410x.1999.00217.x
    • Knowles MA: The genetics of transitional cell carcinoma: progress and potential clinical application. BJU Int 84: 412-427, 1999. (Pubitemid 29419407)
    • (1999) BJU International , vol.84 , Issue.4 , pp. 412-427
    • Knowles, M.A.1
  • 4
    • 0034923357 scopus 로고    scopus 로고
    • Bladder cancer: I. Molecular and genetic basis of carcinogenesis
    • DOI 10.1159/000052494
    • Brandau S and Böhle A: Bladder cancer. I. Molecular and genetic basis of carcinogenesis. Eur Urol 39: 491-497, 2001. (Pubitemid 32678962)
    • (2001) European Urology , vol.39 , Issue.5 , pp. 491-497
    • Brandau, S.1    Bohle, A.2
  • 5
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O: On the origin of cancer cells. Science 123: 309-314, 1956.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 6
    • 0017841405 scopus 로고
    • Tumor mitochondria and the bioenergetics of cancer cells
    • Pederson PL: Tumor mitochondria and the bioenergetics of cancer cells. Prog Exp Tumor Res 22: 190-274, 1978.
    • (1978) Prog Exp Tumor Res , vol.22 , pp. 190-274
    • Pederson, P.L.1
  • 7
    • 0016574783 scopus 로고
    • Is there a role for mitochondrial genes in carcinogenesis?
    • Hoberman HD: Is there a role for mitochondrial genes in carcinogenesis? Cancer Res 35: 3332-3335, 1975.
    • (1975) Cancer Res , vol.35 , pp. 3332-3335
    • Hoberman, H.D.1
  • 8
    • 0019423856 scopus 로고
    • Sequence and organization of the human mitochondrial genome
    • DOI 10.1038/290457a0
    • Anderson S, Bankier AT, Barrell BG, De Bruijn MHL, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F, Schreier PH, Smith AJH, Staden R and Young IG: Sequence and organization of the human mitochondrial genome. Nature 290: 457-465, 1981. (Pubitemid 11159074)
    • (1981) Nature , vol.290 , Issue.5806 , pp. 457-465
    • Anderson, S.1    Bankier, A.T.2    Barrell, B.G.3
  • 10
    • 0014801929 scopus 로고
    • Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea
    • Wunderlich V, Schütt M, Böttger M and Graffi A: Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea. Biochem J 118: 99-109, 1970.
    • (1970) Biochem J , vol.118 , pp. 99-109
    • Wunderlich, V.1    Schütt, M.2    Böttger, M.3    Graffi, A.4
  • 11
    • 0019306958 scopus 로고
    • Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA
    • DOI 10.1038/287244a0
    • Allen JA and Coombs MM: Colvant binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA. Nature 287: 244-245, 1980. (Pubitemid 10019777)
    • (1980) Nature , vol.287 , Issue.5779 , pp. 244-245
    • Allen, J.A.1    Coombs, M.M.2
  • 12
    • 0019306621 scopus 로고
    • Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene
    • Backer JM and Weinstein IB: Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a] pyrene. Science 209: 297-299, 1980. (Pubitemid 10007166)
    • (1980) Science , vol.209 , Issue.4453 , pp. 297-299
    • Backer, J.M.1    Weinstein, I.B.2
  • 15
    • 0020030587 scopus 로고
    • The effect of benzo[a]pyrene on DNA synthesis and DNA polymerase activity of rat liver mitochondria
    • DOI 10.1016/0014-5793(82)80391-8
    • Salazar I, Tarrago-Litvak L, Gil L and Litvak S: The effect of benzo[a]pyrene on DNA synthesis and DNA polymerase activity of rat liver mitochondria. FEBS Lett 138: 45-49, 1982. (Pubitemid 12159347)
    • (1982) FEBS Letters , vol.138 , Issue.1 , pp. 45-49
    • Salazar, I.1    Tarrago-Litvak, L.2    Gil, L.3    Litvak, S.4
  • 17
    • 0018749490 scopus 로고
    • Role of superoxide dismutase in cancer: A review
    • Oberley LW and Buettner GR: Role of superoxide dismutase in cancer: a review. Cancer Res 39: 1141-1149, 1979. (Pubitemid 9183825)
    • (1979) Cancer Research , vol.39 , Issue.4 , pp. 1141-1149
    • Oberley, L.W.1    Buettner, G.R.2
  • 20
    • 0000825475 scopus 로고
    • The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria
    • Clayton DA, Doda JN and Friedberg EC: The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. Proc Natl Acad Sci USA 71: 2777-2781, 1974.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2777-2781
    • Clayton, D.A.1    Doda, J.N.2    Friedberg, E.C.3
  • 22
    • 0030881789 scopus 로고    scopus 로고
    • Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells
    • DOI 10.1074/jbc.272.41.25409
    • Croteau DL and Bohr VA: Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem 272: 25409-25412, 1997. (Pubitemid 27438839)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.41 , pp. 25409-25412
    • Croteau, D.L.1    Bohr, V.A.2
  • 23
    • 0019861198 scopus 로고
    • Fidelity of mammalian DNA polymerases
    • Kunkel TA and Loeb LA: Fidelity of mammalian DNA polymerases. Science 213: 765-767, 1981. (Pubitemid 11016452)
    • (1981) Science , vol.213 , Issue.4509 , pp. 765-767
    • Kunkel, T.A.1    Loeb, L.A.2
  • 26
    • 0030925951 scopus 로고    scopus 로고
    • Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis
    • DOI 10.1002/elps.1150180504
    • Alonso A, Martin P, Albarran C, Aguilera B, Garcia O, Guzman A, Oliva H and Sancho M: Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis. Electrophoresis 18: 682-685, 1997. (Pubitemid 27226964)
    • (1997) Electrophoresis , vol.18 , Issue.5 , pp. 682-685
    • Alonso, A.1    Martin, P.2    Albarran, C.3    Aguilera, B.4    Garcia, O.5    Guzman, A.6    Oliva, H.7    Sancho, M.8
  • 28
    • 0034109860 scopus 로고    scopus 로고
    • Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma
    • Habano W, Sugai T, Nakamura SI, Uesugi N, Yoshida T and Sasou S: Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma. Gastroenterology 118: 835-841, 2000. (Pubitemid 30243746)
    • (2000) Gastroenterology , vol.118 , Issue.5 , pp. 835-841
    • Habano, W.1    Sugai, T.2    Nakamura, S.3    Uesugi, N.4    Yoshida, T.5    Sasou, S.6
  • 29
    • 0034854114 scopus 로고    scopus 로고
    • Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma
    • Máximo V, Soares P, Seruca R, Rocha AS, Castro P and Sobrinho-Simões M: Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma. Genes Chromosomes Cancer 32: 136-143, 2001.
    • (2001) Genes Chromosomes Cancer , vol.32 , pp. 136-143
    • Máximo, V.1    Soares, P.2    Seruca, R.3    Rocha, A.S.4    Castro, P.5    Sobrinho-Simões, M.6
  • 31
    • 0036187963 scopus 로고    scopus 로고
    • Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma
    • Nomoto S, Yamashita K, Koshikawa K, Nakao A and Sidransky D: Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma. Clin Cancer Res 8: 481-487, 2002. (Pubitemid 34193968)
    • (2002) Clinical Cancer Research , vol.8 , Issue.2 , pp. 481-487
    • Nomoto, S.1    Yamashita, K.2    Koshikawa, K.3    Nakao, A.4    Sidransky, D.5
  • 32
    • 0032532559 scopus 로고    scopus 로고
    • Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: Evidence for mismatch repair systems in mitochondrial genome
    • Habano W, Nakamura SI and Sugai T: Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome. Oncogene 17: 1931-1937, 1998. (Pubitemid 28488461)
    • (1998) Oncogene , vol.17 , Issue.15 , pp. 1931-1937
    • Habano, W.1    Nakamura, S.-I.2    Sugai, T.3
  • 33
    • 0032729633 scopus 로고    scopus 로고
    • Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability
    • DOI 10.1002/(SICI)1097-0215(19991126)83:5<625::AID
    • Habano W, Sugai T, Yoshida T and Nakamura SI: Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability. Int J Cancer 83: 625-629, 1999. (Pubitemid 29508041)
    • (1999) International Journal of Cancer , vol.83 , Issue.5 , pp. 625-629
    • Habano, W.1    Sugai, T.2    Yoshida, T.3    Nakamura, S.-I.4
  • 37
  • 38
    • 0028265754 scopus 로고
    • Analysis of nuclear and mitochondrial DNA alterations in thyroid and renal oncocytic tumors
    • Tallini G, Ladanyi M, Rosai J and Jhanwar SC: Analysis of nuclear and mitochondrial DNA alterations in thyroid and renal oncocytic tumors. Cytogenet Cell Genet 66: 253-259, 1994. (Pubitemid 24144086)
    • (1994) Cytogenetics and Cell Genetics , vol.66 , Issue.4 , pp. 253-259
    • Tallini, G.1    Ladanyi, M.2    Rosai, J.3    Jhanwar, S.C.4
  • 40
    • 0029865312 scopus 로고    scopus 로고
    • Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma
    • Selvanayagam P and Rajaraman S: Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma. Lab Invest 74: 592-599, 1996. (Pubitemid 26105720)
    • (1996) Laboratory Investigation , vol.74 , Issue.3 , pp. 592-599
    • Selvanayagam, P.1    Rajaraman, S.2
  • 42
    • 0037314430 scopus 로고    scopus 로고
    • Mutations of mtDNA in renal cell tumours arising in end-stage renal disease
    • DOI 10.1002/path.1273
    • Nagy A, Wilhelm M and Kovacs G: Mutations of mtDNA in renal cell tumours arising in end-stage renal disease. J Pathol 199: 237-242, 2003. (Pubitemid 36176030)
    • (2003) Journal of Pathology , vol.199 , Issue.2 , pp. 237-242
    • Nagy, A.1    Wilhelm, M.2    Kovacs, G.3
  • 43
    • 0039250954 scopus 로고    scopus 로고
    • Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
    • DOI 10.1126/science.287.5460.2017
    • Fliss MS, Usadel H, Caballero OL, Wu L, Buta MR, Eleff SM, Jen J and Sidransky D: Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287: 2017-2019, 2000. (Pubitemid 30158678)
    • (2000) Science , vol.287 , Issue.5460 , pp. 2017-2019
    • Fliss, M.S.1    Usadel, H.2    Caballero, O.L.3    Wu, L.4    Buta, M.R.5    Eleff, S.M.6    Jen, J.7    Sidransky, D.8
  • 46
    • 0035216885 scopus 로고    scopus 로고
    • Accumulation of mitochondrial DNA deletions in the malignant prostate of patients of different ages
    • DOI 10.1016/S0531-5565(01)00153-X, PII S053155650100153X
    • Jessie BC, Sun CQ, Irons HR, Marshall FF, Wallace DC and Petros JA: Accumulation of mitochondrial DNA deletions in the malignant prostate of patients of different ages. Exp Gerontol 37: 169-174, 2001. (Pubitemid 33152708)
    • (2001) Experimental Gerontology , vol.37 , Issue.1 , pp. 169-174
    • Jessie, B.C.1    Sun, C.Q.2    Irons, H.R.3    Marshall, F.F.4    Wallace, D.C.5    Petros, J.A.6
  • 47
    • 0037112431 scopus 로고    scopus 로고
    • Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection
    • Chen JZ, Gokden N, Greene GF, Mukunyadzi P and Kadlubar FF: Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection. Cancer Res 62: 6470-6474, 2002. (Pubitemid 35364109)
    • (2002) Cancer Research , vol.62 , Issue.22 , pp. 6470-6474
    • Chen, J.Z.1    Gokden, N.2    Greene, G.F.3    Mukunyadzi, P.4    Kadlubar, F.F.5
  • 49
    • 0029019959 scopus 로고
    • Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients
    • Bianchi MS, Bianchi NO and Bailliet G: Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients. Cytogenet Cell Genet 71: 99-103, 1995.
    • (1995) Cytogenet Cell Genet , vol.71 , pp. 99-103
    • Bianchi, M.S.1    Bianchi, N.O.2    Bailliet, G.3
  • 52
    • 0036170578 scopus 로고    scopus 로고
    • Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer
    • Tan DJ, Bai RK and Wong LJC: Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res 62: 972-976, 2002.
    • (2002) Cancer Res , vol.62 , pp. 972-976
    • Tan, D.J.1    Bai, R.K.2    Wong, L.J.C.3
  • 53
    • 0035958278 scopus 로고    scopus 로고
    • Accumulation of mitochondrial DNA deletions in human oral tissues - Effects of betel quid chewing and oral cancer
    • Lee HC, Yin PH, Yu TN, Chang YD, Hsu WC, Kao SY, Chi CW, Liu TY and Wei YH: Accumulation of mitochondrial DNA deletions in human oral tissues - effects of betel quid chewing and oral cancer. Mutat Res 493: 67-74, 2001.
    • (2001) Mutat Res , vol.493 , pp. 67-74
    • Lee, H.C.1    Yin, P.H.2    Yu, T.N.3    Chang, Y.D.4    Hsu, W.C.5    Kao, S.Y.6    Chi, C.W.7    Liu, T.Y.8    Wei, Y.H.9
  • 54
    • 0038070419 scopus 로고    scopus 로고
    • Novel heteroplasmic frameshift and missense somatic mitochondrial DNA mutations in oral cancer of betel quid chewers
    • DOI 10.1002/gcc.10217
    • Tan DJ, Chang J, Chen WL, Agress LJ, Yeh KT, Wang B and Wong LJC: Novel heteroplasmic frameshift and missense somatic mitochondrial DNA mutations in oral cancer of betel quid chewers. Genes Chromosomes Cancer 37: 186-194, 2003. (Pubitemid 36529786)
    • (2003) Genes Chromosomes and Cancer , vol.37 , Issue.2 , pp. 186-194
    • Tan, D.-J.1    Chang, J.2    Chen, W.-L.3    Agress, L.J.4    Yeh, K.-T.5    Wang, B.6    Wong, L.-J.C.7
  • 55
    • 0037242343 scopus 로고    scopus 로고
    • Mitochondrial DNA mutation correlates with stage progression and prognosis in non-small cell lung cancer
    • DOI 10.1002/humu.10196
    • Matsuyama W, Nakagawa M, Wakimoto J, Hirotsu Y, Kawabata M and Osame M: Mitochondrial DNA mutation correlates with stage progression and prognosis in non-small cell lung cancer. Hum Mutat 21: 441-443, 2003. (Pubitemid 36389833)
    • (2003) Human Mutation , vol.21 , Issue.4 , pp. 441-443
    • Matsuyama, W.1    Nakagawa, M.2    Wakimoto, J.3    Hirotsu, Y.4    Kawabata, M.5    Osame, M.6
  • 56
    • 0034643388 scopus 로고    scopus 로고
    • Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours
    • Yeh JJ, Lunetta KL, van Orsouw NJ, Moore FD Jr, Mutter GL, Vijg J, Dahia PLM and Eng C: Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene 19: 2060-2066, 2000. (Pubitemid 30229419)
    • (2000) Oncogene , vol.19 , Issue.16 , pp. 2060-2066
    • Yeh, J.J.1    Lunetta, K.L.2    Van Orsouw, N.J.3    Moore Jr., F.D.4    Mutter, G.L.5    Vijg, J.6    Dahia, P.L.7    Eng, C.8
  • 57
    • 0036799079 scopus 로고    scopus 로고
    • Differential mutation frequency in mitochondrial DNA from thyroid tumours
    • Lohrer HD, Hieber L and Zitzelsberger H: Differential mutation frequency in mitochondrial DNA from thyroid tumours. Carcinogenesis 23: 1577-1582, 2002. (Pubitemid 35214941)
    • (2002) Carcinogenesis , vol.23 , Issue.10 , pp. 1577-1582
    • Lohrer, H.D.1    Hieber, L.2    Zitzelsberger, H.3
  • 58
    • 0036095510 scopus 로고    scopus 로고
    • Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology. A study with emphasis on Hürthle cell tumors
    • Máximo V, Soares P, Lima J, Cameselle-Teijeiro J and Sobrinho-Simões M: Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology. A study with emphasis on Hürthle cell tumors. Am J Pathol 160: 1857-1865, 2002.
    • (2002) Am J Pathol , vol.160 , pp. 1857-1865
    • Máximo, V.1    Soares, P.2    Lima, J.3    Cameselle-Teijeiro, J.4    Sobrinho-Simões, M.5
  • 62
    • 0014557091 scopus 로고
    • Histogenesis of urinary bladder tumors induced by N-butyl-N- (4hydroxybutyl) nitrosamine in rats
    • Ito N, Hiasa Y, Tamai A, Okajima E and Kitamura H: Histogenesis of urinary bladder tumors induced by N-butyl-N-(4hydroxybutyl) nitrosamine in rats. Gann 60: 401-410, 1969.
    • (1969) Gann , vol.60 , pp. 401-410
    • Ito, N.1    Hiasa, Y.2    Tamai, A.3    Okajima, E.4    Kitamura, H.5
  • 63
    • 0020360521 scopus 로고
    • Histopathological analysis of preneoplastic changes during N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats
    • Fukushima S, Murasaki G, Hirose M, Nakanishi K, Haegawa R and Ito N: Histopathological analysis of preneoplastic changes during N-butyl-N-(4- hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats. Acta Pathol Jpn 32: 243-250, 1982. (Pubitemid 13229315)
    • (1982) Acta Pathologica Japonica , vol.32 , Issue.2 , pp. 243-250
    • Fukushima, S.1    Murasaki, G.2    Hirose, M.3
  • 64
    • 0023909036 scopus 로고
    • Strain differences in N-butyl-N-(4-hydroxybutyl) nitrosamine bladder carcinogenesis in rats
    • Nakanowatari J, Fukushima S, Imaida K, Ito N and Nagase S: Strain differences in N-butyl-N-(4-hydroxybutyl) nitrosamine bladder carcinogenesis in rats. Jpn J Cancer Res 79: 453-459, 1988.
    • (1988) Jpn J Cancer Res , vol.79 , pp. 453-459
    • Nakanowatari, J.1    Fukushima, S.2    Imaida, K.3    Ito, N.4    Nagase, S.5
  • 65
    • 0031035454 scopus 로고    scopus 로고
    • Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes: Support for a genetic bottleneck
    • Marchington DR, Hartshorne GM, Barlow D and Poulton J: Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes: support for a genetic bottleneck. Am J Hum Genet 60: 408-416, 1997. (Pubitemid 27058412)
    • (1997) American Journal of Human Genetics , vol.60 , Issue.2 , pp. 408-416
    • Marchington, D.R.1    Hartshorne, G.M.2    Barlow, D.3    Poulton, J.4
  • 67
    • 0027058592 scopus 로고
    • Transcription and replication of animal mitochondrial DNAs
    • Clayton DA: Transcription and replication of animal mitochondrial DNAs. Int Rev Cytol 141: 217-232, 1992.
    • (1992) Int Rev Cytol , vol.141 , pp. 217-232
    • Clayton, D.A.1
  • 68
    • 0029881588 scopus 로고    scopus 로고
    • Do sequence variants in the major non-coding region of the mitochondrial genome influence mitochondrial mutations associated with disease?
    • DOI 10.1093/hmg/5.4.473
    • Marchington DR, Poulton J, Sellar A and Holt IJ: Do sequence variants in the major non-coding region of the mitochondrial genome influence mitochondrial mutations associated with disease? Hum Mol Genet 5: 473-479, 1996. (Pubitemid 26101142)
    • (1996) Human Molecular Genetics , vol.5 , Issue.4 , pp. 473-479
    • Marchington, D.R.1    Poulton, J.2    Sellar, A.3    Holt, I.J.4
  • 69
    • 0036716827 scopus 로고    scopus 로고
    • Detection of mitochondrial DNA alterations in the serum of hepatocellular carcinoma patients
    • Okochi O, Hibi K, Uemura T, Inoue S, Takeda S, Kaneko T and Nakao A: Detection of mitochondrial DNA alterations in the serum of hepatocellular carcinoma patients. Clin Cancer Res 8: 2875-2878, 2002. (Pubitemid 35025733)
    • (2002) Clinical Cancer Research , vol.8 , Issue.9 , pp. 2875-2878
    • Okochi, O.1    Hibi, K.2    Uemura, T.3    Inoue, S.4    Takeda, S.5    Kaneko, T.6    Nakao, A.7
  • 71
    • 0023680957 scopus 로고
    • Two distinct mechanisms for deletion in mitochondrial DNA of Schizosaccharomyces pombe mutator strains
    • Ahne A, Muller-Derlich J, Merlos-Lange AM, Kanbay F, Wolf K and Lang BF: Two distinct mechanisms for deletion in mitochondrial DNA of Schizosaccharomyces pombe mutator strains. J Mol Biol 202: 725-734, 1988.
    • (1988) J Mol Biol , vol.202 , pp. 725-734
    • Ahne, A.1    Muller-Derlich, J.2    Merlos-Lange, A.M.3    Kanbay, F.4    Wolf, K.5    Lang, B.F.6


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