Effects of nitric oxide synthase isoform deletion on oxytocin and vasopressin messenger RNA in mouse hypothalamus

NeuroReport

Volumn 16, Issue 4, 2005, Pages 413-417

  Nomura, Masayoshi ^a   Tsutsui, Masato ^a   Shimokawa, Hiroaki ^b   Fujimoto, Naohiro ^a   Ueta, Yoichi ^a   Morishita, Tsuyoshi ^a   Yanagihara, Nobuyuki ^a   Matsumoto, Tetsuro ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Arginine vasopressin; In situ hybridization histochemistry; Knockout mice; Nitric oxide synthase; Oxytocin

Indexed keywords

MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYTOCIN; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR COMMISSURE; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRIA TERMINALIS; SUPRACHIASMATIC NUCLEUS; SUPRAOPTIC NUCLEUS; THALAMUS MIDLINE NUCLEUS;

ANIMALS; GENE DELETION; HYPOTHALAMUS; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; OXYTOCIN; RNA, MESSENGER; VASOPRESSINS;

EID: 15944380107     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200503150-00021     Document Type: Article

References (20)

1. Nelson RJ, Kriegsfeld LJ, Dawson VL, Dawson TM. Effects of nitric oxide on neuroendocrine function and behavior. Front Neuroendocrinol 1997; 18:463-491.
2. Vernet D, Bonavera JJ, Swerdloff RS, Gonzalez-Cadavid NF, Wang C. Spontaneous expression of inducible nitric oxide synthase in the hypothalamus and other brain regions of aging rats. Endocrinology 1998; 139:3254-3261.
3. Caillol M, Devinoy E, Lacroix MC, Schirar A. Endothelial and neuronal nitric oxide synthases are present in the suprachiasmatic nuclei of Syrian hamsters and rats. Eur J Neurosci 2000; 12:649-661.
4. Huang PL, Dawson TM, Bredt DS, Snyder SH, Fishman MC. Targeted disruption of the neuronal nitric oxide synthase gene. Cell 1993; 75:1273-1286.
5. Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995; 377:239-242.
6. MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M et al. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995; 81:641-650.
7. Nelson RJ, Demas GE, Huang PL, Fishman MC, Dawson VL, Dawson TM et al. Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature 1995; 378:383-386.
8. Kriegsfeld LJ, Eliasson MJ, Demas GE, Blackshaw S, Dawson TM, Nelson RJ et al. Nocturnal motor coordination deficits in neuronal nitric oxide synthase knock-out mice. Neuroscience 1999; 89:311-315.
9. Jablonka-Shariff A, Ravi S, Beltsos AN, Murphy LL, Olson LM. Abnormal estrous cyclicity after disruption of endothelial and inducible nitric oxide synthase in mice. Biol Reprod 1999; 61:171-177.
10. Kadekaro M, Liu H, Terrell ML, Gesti S, Bui V, Summy-Long JY. Role of NO on vasopressin and oxytocin release and blood pressure responses during osmotic stimulation in rats. Am J Physiol Regul Integr Comp Physiol 1997; 273:R1024-R1030.
11. Nomura M, McKenna E, Korach KS, Pfaff DW, Ogawa S. Estrogen receptor-β regulates transcript levels for oxytocin and arginine vasopressin in the hypothalamic paraventricular nucleus of male mice. Brain Res Mol Brain Res 2002; 109:84-94.
12. Franklin KBJ, Paxinos G. The Mouse Brain Stereotaxic Coordinates. Toronto: Academic Press; 1997.
13. Bernstein HG, Keilhoff G, Seidel B, Stanarius A, Huang PL, Fishman MC et al. Expression of hypothalamic peptides in mice lacking neuronal nitric oxide synthase: reduced β-END immunoreactivity in the arcuate nucleus. Neuroendocrinology 1998; 68:403-411.
14. Stern JE. Nitric oxide and homeostatic control: an intercellular signalling molecule contributing to autonomic and neuroendocrine integration? Prog Biophys Mol Biol 2004; 84:197-215.
15. Chiavegatto S, Nelson RJ. Interaction of nitric oxide and serotonin in aggressive behavior. Horm Behav 2003; 44:233-241.
16. Harmon AC, Huhman KL, Moore TO, Albers HE. Oxytocin inhibits aggression in female Syrian hamsters. J Neuroendocrinol 2002; 14:963-969.
17. Giovenardi M, Padoin MJ, Cadore LP, Lucion AB. Hypothalamic pararentricular nucleus modulates maternal aggression in rats: effects of ibotenic acid lesion and oxytocin antisense. Physiol Behav 1998; 63:351-359.
18. Albert DJ, Walsh ML, Gorzalka BB, Mendelson S, Zalys C. Intermale social aggression: suppression by medial preoptic area lesions. Physiol Behav 1986; 38:169-173.
19. Young WS III, Shepard E, DeVries AC, Zimmer A, LaMarca ME, Ginns EI et al. Targeted reduction of oxytocin expression provides insights into its physiological roles. Adv Exp Med Biol 1998; 449:231-240.
20. Winslow JT, Hearn EF, Ferguson J, Young LJ, Matzuk MM, Insel TR. Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse. Horm Behav 2000; 37:145-155.