-
1
-
-
0036676974
-
The unconventional lifestyle of NKT cells
-
Kronenberg, M. and Gapin, L., The unconventional lifestyle of NKT cells. Nat. Rev. Immunol. 2002. 2: 557-568.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 557-568
-
-
Kronenberg, M.1
Gapin, L.2
-
2
-
-
0038228956
-
The regulatory role of Vα14 NKT cells in innate and acquired immune response
-
Taniguchi, M., Harada, M., Kojo, S., Nakayama, T. and Wakao, H., The regulatory role of Vα14 NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 2003. 21: 483-513.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 483-513
-
-
Taniguchi, M.1
Harada, M.2
Kojo, S.3
Nakayama, T.4
Wakao, H.5
-
3
-
-
1242314224
-
CD1d-mediated antigen presentation to natural killer T (NKT) cells
-
Brutkiewicz, R. R., Lin, Y., Cho, S., Hwang, Y. K., Sriram, V. and Roberts, T. J., CD1d-mediated antigen presentation to natural killer T (NKT) cells. Crit. Rev. Immunol. 2003. 23: 403-419.
-
(2003)
Crit. Rev. Immunol.
, vol.23
, pp. 403-419
-
-
Brutkiewicz, R.R.1
Lin, Y.2
Cho, S.3
Hwang, Y.K.4
Sriram, V.5
Roberts, T.J.6
-
4
-
-
0032489652
-
Natural ligand of mouse CD1d1: Cellular glycosylphosphatidylinositol
-
Joyce, S., Woods, A. S., Yewdell, J. W., Bennink, J. R., De Silva, A. D., Boesteanu, A., Balk, S. P., Cotter, R. J. and Brutkiewicz, R. R., Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science 1998. 279: 1541-1544.
-
(1998)
Science
, vol.279
, pp. 1541-1544
-
-
Joyce, S.1
Woods, A.S.2
Yewdell, J.W.3
Bennink, J.R.4
De Silva, A.D.5
Boesteanu, A.6
Balk, S.P.7
Cotter, R.J.8
Brutkiewicz, R.R.9
-
5
-
-
0037080344
-
Lipid protein interactions: The assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum
-
De Silva, A. D., Park, J. J., Matsuki, N., Stanic, A. K., Brutkiewicz, R. R., Medof, M. E. and Joyce, S., Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum. J. Immunol. 2002. 168: 723-733.
-
(2002)
J. Immunol.
, vol.168
, pp. 723-733
-
-
De Silva, A.D.1
Park, J.J.2
Matsuki, N.3
Stanic, A.K.4
Brutkiewicz, R.R.5
Medof, M.E.6
Joyce, S.7
-
6
-
-
0742270963
-
Lipid-protein interactions: Biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved
-
Park, J. J., Kang, S. J., De Silva, A. D., Stanic, A. K., Casorati, G., Hachey, D. L., Cresswell, P. and Joyce, S., Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved. Proc. Natl. Acad. Sci. USA 2004. 101: 1022-1026.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1022-1026
-
-
Park, J.J.1
Kang, S.J.2
De Silva, A.D.3
Stanic, A.K.4
Casorati, G.5
Hachey, D.L.6
Cresswell, P.7
Joyce, S.8
-
7
-
-
13144249230
-
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells
-
Kawano, T., Cui, J., Koezuka, Y., Toura, I., Kaneko, Y., Sato, H., Kondo E., Harada, M., Koseki, H., Nakayama, T., Tanaka, Y. and Taniguchi, M., Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells. Proc. Natl. Acad. Sci. USA 1998. 95: 5690-5693.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5690-5693
-
-
Kawano, T.1
Cui, J.2
Koezuka, Y.3
Toura, I.4
Kaneko, Y.5
Sato, H.6
Kondo, E.7
Harada, M.8
Koseki, H.9
Nakayama, T.10
Tanaka, Y.11
Taniguchi, M.12
-
8
-
-
0037691923
-
The role of natural killer T cells and other T cell subsets against infection by the pre-erythrocytic stages of malaria parasites
-
Schmieg, J., Gonzalez-Aseguinolaza, G. and Tsuji, M., The role of natural killer T cells and other T cell subsets against infection by the pre-erythrocytic stages of malaria parasites. Microbes Infect. 2003. 5: 499-506.
-
(2003)
Microbes Infect.
, vol.5
, pp. 499-506
-
-
Schmieg, J.1
Gonzalez-Aseguinolaza, G.2
Tsuji, M.3
-
9
-
-
0034596944
-
Natural killer T cell activation inhibits hepatitis B virus replication in vivo
-
Kakimi, K., Guidotti, L. G., Koezuka, Y. and Chisari, F. V., Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J. Exp. Med. 2000. 192: 921-930.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 921-930
-
-
Kakimi, K.1
Guidotti, L.G.2
Koezuka, Y.3
Chisari, F.V.4
-
10
-
-
0036008999
-
Natural killer T (NKT) cells and their role in antitumor immunity
-
Brutkiewicz, R. R. and Sriram, V., Natural killer T (NKT) cells and their role in antitumor immunity. Crit. Rev. Oncol./Hematol. 2002. 41: 287-298.
-
(2002)
Crit. Rev. Oncol./Hematol.
, vol.41
, pp. 287-298
-
-
Brutkiewicz, R.R.1
Sriram, V.2
-
11
-
-
0034799397
-
Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
-
Sharif, S., Arreaza, G. A., Zucker, P., Mi, Q. S., Sondhi, J., Naidenko, O.V., Kronenberg, M., Koezuka, Y., Delovitch, T. L., Gombert, J. M., Leite-De-Moraes, M., Gouarin, C., Zhu, R., Hameg, A., Nakayama, T., Taniguchi, M., Lepault, F., Lehuen, A., Bach, J. F. and Herbelin, A., Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat. Med. 2001. 7: 1057-1062.
-
(2001)
Nat. Med.
, vol.7
, pp. 1057-1062
-
-
Sharif, S.1
Arreaza, G.A.2
Zucker, P.3
Mi, Q.S.4
Sondhi, J.5
Naidenko, O.V.6
Kronenberg, M.7
Koezuka, Y.8
Delovitch, T.L.9
Gombert, J.M.10
Leite-De-Moraes, M.11
Gouarin, C.12
Zhu, R.13
Hameg, A.14
Nakayama, T.15
Taniguchi, M.16
Lepault, F.17
Lehuen, A.18
Bach, J.F.19
Herbelin, A.20
more..
-
13
-
-
0034757148
-
Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus
-
Hobbs, J. A., Cho, S., Roberts, T. J., Sriram, V., Zhang, J., Xu, M. and Brutkiewicz, R. R., Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus. J. Virol. 2001. 75: 10746-10754.
-
(2001)
J. Virol.
, vol.75
, pp. 10746-10754
-
-
Hobbs, J.A.1
Cho, S.2
Roberts, T.J.3
Sriram, V.4
Zhang, J.5
Xu, M.6
Brutkiewicz, R.R.7
-
14
-
-
0029582927
-
+ TCR α /β intermediate liver lymphocytes are down-regulated by Listeria monocytogenes
-
+ TCR α /β intermediate liver lymphocytes are down-regulated by Listeria monocytogenes. Eur. J. Immunol. 1995. 25: 3321-3325.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 3321-3325
-
-
Emoto, M.1
Emoto, Y.2
Kaufmann, S.H.3
-
15
-
-
0037108604
-
The innate immune response differs in primary and secondary Salmonella infection
-
Kirby, A. C., Yrlid, U. and Wick, M. J., The innate immune response differs in primary and secondary Salmonella infection. J. Immunol. 2002. 169: 4450-4459.
-
(2002)
J. Immunol.
, vol.169
, pp. 4450-4459
-
-
Kirby, A.C.1
Yrlid, U.2
Wick, M.J.3
-
16
-
-
0034667992
-
Fas/Fas ligand interactions promote activation-induced cell death of NK T lymphocytes
-
Leite-De-Moraes, M. C., Herbelin, A., Gouarin, C., Koezuka, Y., Schneider, E. and Dy, M., Fas/Fas ligand interactions promote activation-induced cell death of NK T lymphocytes. J. Immunol. 2000. 165: 4367-4371.
-
(2000)
J. Immunol.
, vol.165
, pp. 4367-4371
-
-
Leite-De-Moraes, M.C.1
Herbelin, A.2
Gouarin, C.3
Koezuka, Y.4
Schneider, E.5
Dy, M.6
-
17
-
-
0032169234
-
Rapid death and regeneration of NKT cells in anti-CD3E- or IL-12-treated mice: A major role for bone marrow in NKT homeostasis
-
Eberl, G. and MacDonald, H. R., Rapid death and regeneration of NKT cells in anti-CD3E- or IL-12-treated mice: a major role for bone marrow in NKT homeostasis. Immunity 1998. 9: 345-353.
-
(1998)
Immunity
, vol.9
, pp. 345-353
-
-
Eberl, G.1
MacDonald, H.R.2
-
18
-
-
0141958207
-
Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells
-
Crowe, N. Y., Uldrich, A. P., Kyparissoudis, K., Hammond, K. J., Hayakawa, Y., Sidobre, S., Keating, R., Kronenberg, M., Smyth, M. J. and Godfrey, D. I., Glycolipid antigen drives rapid expansion and sustained cytokine production by NK T cells. J. Immunol. 2003. 171: 4020-4027.
-
(2003)
J. Immunol.
, vol.171
, pp. 4020-4027
-
-
Crowe, N.Y.1
Uldrich, A.P.2
Kyparissoudis, K.3
Hammond, K.J.4
Hayakawa, Y.5
Sidobre, S.6
Keating, R.7
Kronenberg, M.8
Smyth, M.J.9
Godfrey, D.I.10
-
19
-
-
0141814650
-
The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion
-
Wilson, M. T., Johansson, C., Olivares-Villagomez, D., Singh, A. K., Stanic, A. K., Wang, C. R., Joyce, S., Wick, M. J. and Van Kaer, L., The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proc. Natl. Acad. Sci. USA 2003. 100: 10913-10918.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10913-10918
-
-
Wilson, M.T.1
Johansson, C.2
Olivares-Villagomez, D.3
Singh, A.K.4
Stanic, A.K.5
Wang, C.R.6
Joyce, S.7
Wick, M.J.8
Van Kaer, L.9
-
20
-
-
1042280962
-
Down-regulation of the invariant Valpha14 antigen receptor in NKT cells upon activation
-
Harada, M., Seino, K., Wakao, H., Sakata, S., Ishizuka, Y., Ito, T., Kojo, S., Nakayama, T. and Taniguchi, M., Down-regulation of the invariant Valpha14 antigen receptor in NKT cells upon activation. Int. Immunol. 2004. 16: 241-247.
-
(2004)
Int. Immunol.
, vol.16
, pp. 241-247
-
-
Harada, M.1
Seino, K.2
Wakao, H.3
Sakata, S.4
Ishizuka, Y.5
Ito, T.6
Kojo, S.7
Nakayama, T.8
Taniguchi, M.9
-
21
-
-
0034608345
-
In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers
-
Benlagha, K., Weiss, A., Beavis, A., Teyton, L. and Bendelac, A., In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J. Exp. Med. 2000. 191: 1895-1904.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1895-1904
-
-
Benlagha, K.1
Weiss, A.2
Beavis, A.3
Teyton, L.4
Bendelac, A.5
-
22
-
-
0034605065
-
Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers
-
Matsuda, J. L., Naidenko, O. V., Gapin, L., Nakayama, T., Taniguchi, M., Wang, C. R., Koezuka, Y. and Kronenberg, M., Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 2000. 192: 741-754.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 741-754
-
-
Matsuda, J.L.1
Naidenko, O.V.2
Gapin, L.3
Nakayama, T.4
Taniguchi, M.5
Wang, C.R.6
Koezuka, Y.7
Kronenberg, M.8
-
26
-
-
0028942106
-
Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro
-
Homburg, C. H., de Haas, M., von dem Borne, A. E., Verhoeven, A. J., Reutelingsperger, C. P. and Roos, D., Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro. Blood 1995. 85: 532-540.
-
(1995)
Blood
, vol.85
, pp. 532-540
-
-
Homburg, C.H.1
de Haas, M.2
von dem Borne, A.E.3
Verhoeven, A.J.4
Reutelingsperger, C.P.5
Roos, D.6
-
27
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
-
Vermes, I., Haanen, C., Steffens-Nakken, H. and Reutelingsperger, C., A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J. Immunol. Methods 1995. 184: 39-51.
-
(1995)
J. Immunol. Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
28
-
-
0022998745
-
Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection
-
McIntyre, K. W. and Welsh, R. M., Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection. J. Exp. Med. 1986. 164: 1667-1681.
-
(1986)
J. Exp. Med.
, vol.164
, pp. 1667-1681
-
-
McIntyre, K.W.1
Welsh, R.M.2
-
29
-
-
0347776209
-
Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
-
Brigl, M., Bry, L., Kent, S. C., Gumperz, J. E. and Brenner, M. B., Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat. Immunol. 2003. 4: 1230-1237.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1230-1237
-
-
Brigl, M.1
Bry, L.2
Kent, S.C.3
Gumperz, J.E.4
Brenner, M.B.5
-
31
-
-
0032193207
-
+ NK T lymphocytes
-
+ NK T lymphocytes. J. Immunol. 1998. 161: 3271-3281.
-
(1998)
J. Immunol.
, vol.161
, pp. 3271-3281
-
-
Burdin, N.1
Brossay, L.2
Koezuka, Y.3
Smiley, S.T.4
Grusby, M.J.5
Gui, M.6
Taniguchi, M.7
Hayakawa, K.8
Kronenberg, M.9
-
32
-
-
0030060232
-
An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections
-
Orange, J. S. and Biron, C. A., An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections. J. Immunol. 1996. 156: 1138-1142.
-
(1996)
J. Immunol.
, vol.156
, pp. 1138-1142
-
-
Orange, J.S.1
Biron, C.A.2
-
33
-
-
0036604201
-
Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells
-
Roberts, T. J., Sriram, V., Spence, P. M., Gui, M., Hayakawa, K., Bacik, I., Bennink, J. R., Yewdell, J. W. and Brutkiewicz, R. R., Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells. J. Immunol. 2002. 168: 5409-5414.
-
(2002)
J. Immunol.
, vol.168
, pp. 5409-5414
-
-
Roberts, T.J.1
Sriram, V.2
Spence, P.M.3
Gui, M.4
Hayakawa, K.5
Bacik, I.6
Bennink, J.R.7
Yewdell, J.W.8
Brutkiewicz, R.R.9
-
34
-
-
0036310371
-
+ Vα24 natural killer T cells in human immunodeficiency virus infection
-
+ Vα24 natural killer T cells in human immunodeficiency virus infection. J. Virol. 2002. 76: 7528-7534.
-
(2002)
J. Virol.
, vol.76
, pp. 7528-7534
-
-
Sandberg, J.K.1
Fast, N.M.2
Palacios, E.H.3
Fennelly, G.4
Dobroszycki, J.5
Palumbo, P.6
Wiznia, A.7
Grant, R.M.8
Bhardwaj, N.9
Rosenberg, M.G.10
Nixon, D.F.11
-
35
-
-
0036534552
-
CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection
-
Motsinger, A., Haas, D. W., Stanic, A. K., Van Kaer, L., Joyce, S. and Unutmaz, D., CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. J. Exp. Med. 2002. 195: 869-879.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 869-879
-
-
Motsinger, A.1
Haas, D.W.2
Stanic, A.K.3
Van Kaer, L.4
Joyce, S.5
Unutmaz, D.6
-
36
-
-
0036467364
-
+ NKT cells during HIV type 1 infection
-
+ NKT cells during HIV type 1 infection. J. Immunol. 2002. 168: 1490-1495.
-
(2002)
J. Immunol.
, vol.168
, pp. 1490-1495
-
-
van der Vliet, H.J.1
von Blomberg, B.M.2
Hazenberg, M.D.3
Nishi, N.4
Otto, S.A.5
van Benthem, B.H.6
Prins, M.7
Claessen, F.A.8
van den Eertwegh, A.J.9
Giaccone, G.10
-
37
-
-
0037302303
-
Frequency and phenotype of circulating Vα24/Vβ11 double-positive natural killer T cells during hepatitis C virus infection
-
Lucas, M., Gadola, S., Meier, U., Young, N. T., Harcourt, G., Karadimitris, A., Coumi, N., Brown, D., Dusheiko, G., Cerundolo, V. and Klenerman, P., Frequency and phenotype of circulating Vα24 /Vβ11 double-positive natural killer T cells during hepatitis C virus infection. J. Virol. 2003. 77: 2251-2257.
-
(2003)
J. Virol.
, vol.77
, pp. 2251-2257
-
-
Lucas, M.1
Gadola, S.2
Meier, U.3
Young, N.T.4
Harcourt, G.5
Karadimitris, A.6
Coumi, N.7
Brown, D.8
Dusheiko, G.9
Cerundolo, V.10
Klenerman, P.11
-
38
-
-
0037303639
-
Activation of natural killer (NK) T cells during murine cytomegalovirus infection enhances the antiviral response mediated by NK cells
-
Van Dommelen, S. L., Tabarias, H. A., Smyth, M. J. and Degli-Esposti, M. A., Activation of natural killer (NK) T cells during murine cytomegalovirus infection enhances the antiviral response mediated by NK cells. J. Virol 2003. 77: 1877-1884.
-
(2003)
J. Virol.
, vol.77
, pp. 1877-1884
-
-
Van Dommelen, S.L.1
Tabarias, H.A.2
Smyth, M.J.3
Degli-Esposti, M.A.4
-
39
-
-
0031149843
-
The Cmv1 host resistance locus is closely linked to the Ly49 multigene family within the natural killer cell gene complex on mouse chromosome 6
-
Forbes, C. A., Brown, M. G., Cho, R., Shellam, G. R., Yokoyama, W. M. and Scalzo, A. A., The Cmv1 host resistance locus is closely linked to the Ly49 multigene family within the natural killer cell gene complex on mouse chromosome 6. Genomics 1997. 41: 406-413.
-
(1997)
Genomics
, vol.41
, pp. 406-413
-
-
Forbes, C.A.1
Brown, M.G.2
Cho, R.3
Shellam, G.R.4
Yokoyama, W.M.5
Scalzo, A.A.6
-
40
-
-
0035007624
-
CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus
-
Exley, M. A., Bigley, N. J., Cheng, O., Tahir, S. M., Smiley, S. T., Carter, Q. L., Stills, H. F., Grusby, M. J., Koezuka, Y., Taniguchi, M. and Balk, S. P., CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus. J. Leukoc. Biol. 2001. 69: 713-718.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 713-718
-
-
Exley, M.A.1
Bigley, N.J.2
Cheng, O.3
Tahir, S.M.4
Smiley, S.T.5
Carter, Q.L.6
Stills, H.F.7
Grusby, M.J.8
Koezuka, Y.9
Taniguchi, M.10
Balk, S.P.11
-
41
-
-
0037309128
-
Impaired clearance of herpes simplex virus type 1 from mice lacking CD1d or NKT cells expressing the semivariant Vα14-Jα281 TCR
-
Grubor-Bauk, B., Simmons, A., Mayrhofer, G. and Speck, P. G., Impaired clearance of herpes simplex virus type 1 from mice lacking CD1d or NKT cells expressing the semivariant Vα14-Jα281 TCR. J. Immunol. 2003. 170: 1430-1434.
-
(2003)
J. Immunol.
, vol.170
, pp. 1430-1434
-
-
Grubor-Bauk, B.1
Simmons, A.2
Mayrhofer, G.3
Speck, P.G.4
-
43
-
-
1542724500
-
CD1d1-dependent control of the magnitude of an acute antiviral immune response
-
Roberts, T. J., Lin, Y., Spence, P. M., Van Kaer, L. and Brutkiewicz, R. R., CD1d1-dependent control of the magnitude of an acute antiviral immune response. J. Immunol. 2004. 172: 3454-3461.
-
(2004)
J. Immunol.
, vol.172
, pp. 3454-3461
-
-
Roberts, T.J.1
Lin, Y.2
Spence, P.M.3
Van Kaer, L.4
Brutkiewicz, R.R.5
-
44
-
-
0031154578
-
+ T cells lose NK1.1 expression upon in vitro activation
-
+ T cells lose NK1.1 expression upon in vitro activation. J. Immunol. 1997. 158: 5112-5119.11
-
(1997)
J. Immunol.
, vol.158
-
-
Chen, H.1
Huang, H.2
Paul, W.E.3
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