Comparison of substructural epitopes in enzyme active sites using self-organizing maps

Journal of Computer-Aided Molecular Design

Volumn 18, Issue 11, 2004, Pages 697-708

  Kupas, Katrin ^a   Ultsch, Alfred ^a   Klebe, Gerhard ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Data mining; De novo design; Functional comparison of proteins; Self organizing neural networks; U matrix

Indexed keywords

BINDING SITES; CONFORMAL MAPPING; ENZYMES; EPITOPES; LIGANDS; SELF ORGANIZING MAPS;

BINDING CAVITY; DE NOVO DESIGN; ENZYME ACTIVE SITES; FUNCTIONAL COMPARISON OF PROTEIN; LOCAL REGION; MATRIX; PSEUDO CENTERS; SELF-ORGANISING NEURAL NETWORKS; SELF-ORGANIZING-MAPS; U-MATRIX;

DATA MINING;

4 HYDROXYBENZOATE 3 MONOOXYGENASE; ALANINE; ALDEHYDE REDUCTASE; AMINO ACID; ASPARTIC ACID; CARBONATE DEHYDRATASE; EPITOPE; GLUTAMIC ACID; GLUTATHIONE SYNTHASE; ISOCITRATE DEHYDROGENASE; LIGAND; LIGASE; METHIONINE GAMMA LYASE; PHOSPHOGLYCERATE MUTASE; PHOSPHOTRANSFERASE; PROTEIN KINASE; PROTEIN SERINE KINASE; PROTEIN TYROSINE KINASE; PROTEINASE; THREONINE; THYMIDINE PHOSPHATE; URIDINE DIPHOSPHATE; XYLOSE ISOMERASE;

ALGORITHM; ARTICLE; BINDING SITE; CLUSTER ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME STRUCTURE; EPITOPE MAPPING; LIGAND BINDING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SCORING SYSTEM;

EID: 15844385952     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10822-004-6553-x     Document Type: Article

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