Antibodies to soluble liver antigen and α-enolase in patients with autoimmune hepatitis

Journal of Autoimmune Diseases

Volumn 1, Issue , 2004, Pages

  Bogdanos, Dimitrios Petrou ^a   Gilbert, Daniele ^b   Bianchi, Ilaria ^a   Leoni, Simona ^a   Mitry, Ragai R ^a   Ma, Yun ^a   Mieli Vergani, Giorgina ^a   Vergani, Diego ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b UNIVERSITÉ DE ROUEN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENOLASE; LIVER ANTIGEN;

ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY DETECTION; ANTIBODY SPECIFICITY; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; ARTICLE; AUTOIMMUNE HEPATITIS; CONTROLLED STUDY; DNA LIBRARY; DNA PROTEIN COMPLEX; DNA SCREENING; DOT HYBRIDIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; INCUBATION TIME; LIVER HOMOGENATE; NONHUMAN; PROTEOMICS; RAT;

EID: 15744399422     PISSN: 17402557     EISSN: 17402557     Source Type: Journal    
DOI: 10.1186/1740-2557-1-4     Document Type: Article

References (20)

1. Manns M, Gerken G, Kyriatsoulis A, Staritz M, Meyer zum Buschenfelde KH: Characterisation of a new subgroup of autoimmune chronic active hepatitis by autoantibodies against a soluble liver antigen. Lancet 1987, 1:292-294.
2. Wies I, Brunner S, Henninger J, Herkel J, Kanzler S, Meyer zum Buschenfelde KH, Lohse AW: Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis. Lancet 2000, 355:1510-1515.
3. Costa M, Rodriguez-Sanchez JL, Czaja AJ, Gelpi C: Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP(Ser)Sec complex recognized by autoantibodies from patients withtype-1 autoimmune hepatitis. Clin Exp Immunol 2000, 121:364-374.
4. Wen L, Ma Y, Bogdanos DP, Wong FS, Demaine A, Mieli-Vergani G, Vergani D: Pediatric autoimmune liver diseases: the molecular basis of humoral and cellular immunity. Curr Mol Med 2001, 1:379-389.
5. Volkmann M, Martin L, Baurle A, Heid H, Strassburg CP, Trautwein C, Fiehn W, Manns MP: Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis. Hepatology 2001, 33:591-596.
6. Ma Y, Okamoto M, Thomas MG, Bogdanos DP, Lopes AR, Portmann B, Underhill J, Durr R, Mieli-Vergani G, Vergani D: Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease. Hepatology 2002, 35:658-664.
7. Vitozzi S, Djilali-Saiah I, Lapierre P, Alvarez F: Anti-soluble liver antigen/liver-pancreas (SLA/LP) antibodies in pediatric patients with autoimmune hepatitis. Autoimmunity 2002, 35:485-492.
8. Czaja AJ, Shums Z, Norman GL: Frequency and significance of antibodies to soluble liver antigen/liver pancreas in variant autoimmune hepatitis. Autoimmunity 2002, 35:475-483.
9. Baeres M, Herkel J, Czaja AJ, Wies I, Kanzler S, Cancado EL, Porta G, Nishioka M, Simon T, Daehnrich C, Schlumberger W, Galle PR, Lohse AW: Establishment of standardised SLA/LP immunoassays: specificity for autoimmune hepatitis, worldwide occurrence, and clinical characteristics. Gut 2002, 51:259-264.
10. Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G: Pathogenesis of autoimmune hepatitis. Clin Liver Dis 2002, 6:439-449.
11. Ballot E, Bruneel A, Labas V, Johanet C: Identification of rat targets of anti-soluble liver antigen autoantibodies by serologic proteome analysis. Clin Chem 2003, 49:634-643.
12. Adamus G, Amundson D, Seigel GM, Machnicki M: Anti-enolasealpha autoantibodies in cancer-associated retinopathy: epitope mapping and cytotoxicity on retinal cells. J Autoimmun 1998, 11:671-677.
13. Lee KH, Chung HS, Kim HS, Oh SH, Ha MK, Baik JH, Lee S, Bang D: Human alpha-enolase from endothelial cells as a target antigen of anti-endothelial cell antibody in Behcet's disease. Arthritis Rheum 2003, 48:2025-2035.
14. Moodie FD, Leaker B, Cambridge G, Totty NF, Segal AW: Alphaenolase: a novel cytosolic autoantigen in ANCA positive vasculitis. Kidney Int 1993, 43:675-681.
15. Pratesi F, Moscato S, Sabbatini A, Chimenti D, Bombardieri S, Migliorini P: Autoantibodies specific for alpha-enolase in systemic autoimmune disorders. J Rheumatol 2000, 27:109-115.
16. Roozendaal C, Zhao MH, Horst G, Lockwood CM, Kleibeuker JH, Limburg PC, Nelis GF, Kallenberg CG: Catalase and alpha-enolase: two novel granulocyte autoantigens in inflammatory bowel disease (IBD). Clin Exp Immunol 1998, 112:10-16.
17. Saulot V, Vittecoq O, Charlionet R, Fardellone P, Lange C, Marvin L, Machour N, Le Loet X, Gilbert D, Tron F: Presence of autoantibodies to the glycolytic enzyme alpha-enolase in sera from patients with early rheumatoid arthritis. Arthritis Rheum 2002, 46:1196-1201.
18. Tanaka S, Tatsumi KI, Takano T, Murakami Y, Takao T, Yamakita N, Tahara S, Teramoto A, Hashimoto K, Kato Y, Amino N: Anti-alphaenolase antibodies in pituitary disease. Endocr J 2003, 50:697-702.
19. Bogdanos DP, Bianchi I, Ma Y, Mitry RR, Mieli-Vergani G, Vergani D: Targets of antibodies to soluble liver antigen in patients with autoimmune hepatitis. Clin Chem 2004, 50:682-3; author reply 683-4.
20. Bogdanos DP, Pares A, Baum H, Caballeria L, Rigopoulou EI, Ma Y, Burroughs AK, Rodes J, Vergani D: Disease-specific cross-reactivity between mimicking peptides of heat shock protein of mycobacterium gordonae and dominant epitope of E2 subunit of pyruvate dehydrogenase is common in Spanish but not British patients with primary biliary cirrhosis. J Autoimmun 2004, 22:353-362.