Ordering the reductive and cytochrome P450 oxidative steps in demethylsterigmatocystin formation yields general insights into the biosynthesis of aflatoxin and related fungal metabolites

Journal of the American Chemical Society

Volumn 127, Issue 11, 2005, Pages 3724-3733

  Henry, Kevin M ^a   Townsend, Craig A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXINS; BIOSYNTHESIS; CATALYSIS; FUNGI; OXIDATION; PROTONS; REDUCTION; THERMODYNAMICS;

CYTOCHROME; MUTANT STRAIN; OXIDOREDUCTASE; XANTHONE;

PROTEINS;

9 HYDROXYDIHYDRONORSTERIGMATOCYSTIN; AFLATOXIN; AFLATOXIN B1; ANTHRAQUINONE DERIVATIVE; CARCINOGEN; CYTOCHROME P450; MYCOTOXIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; STERIGMATOCYSTIN; UNCLASSIFIED DRUG; VERSICOLORIN A; XANTHONE DERIVATIVE;

ARTICLE; ASPERGILLUS PARASITICUS; BAEYER VILLIGER REACTION; BIOSYNTHESIS; CATALYSIS; DECARBOXYLATION; DEOXYGENATION; EPOXIDATION; FUNGAL METABOLISM; ISOMERIZATION; OXIDATION REDUCTION REACTION; PROTON TRANSPORT; THERMODYNAMICS;

AFLATOXIN B1; ASPERGILLUS; CYTOCHROME P-450 ENZYME SYSTEM; METHYLATION; MODELS, MOLECULAR; NADH, NADPH OXIDOREDUCTASES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; STERIGMATOCYSTIN;

EID: 15744392499     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0455188     Document Type: Article

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