Identification of unknown impurities in simvastatin substance and tablets by liquid chromatography/tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 37, Issue 4, 2005, Pages 715-721

  Vuletić, Marko ^a   Cindrić, Mario ^a   Koružnjak, Jasna Dogan ^a  

^a PLIVA CROATIA LTD   (Croatia)

Author keywords

Identification; Impurities; LC MS MS; Pharmaceuticals; Simvastatin

Indexed keywords

7 [8 (2,2 DIMETHYLBUTYRYLOXY) 2,6 DIMETHYL 1,2,6,7,8,8A HEXAHYDRONAPHTHALEN 1 YL] 3,5 DIHYDROXYHEPTANOIC ACID ETHYL ESTER; ACETONITRILE; DIMETHYL ETHER; ESTER DERIVATIVE; FORMIC ACID; ION; LACTONE; SIMVASTATIN; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANALYTIC METHOD; ARTICLE; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS; MASS SPECTROMETER; MEASUREMENT; MOLECULE; PRECURSOR; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TABLET; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRAVIOLET RADIATION;

EID: 15744385431     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2004.11.047     Document Type: Article

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