High-affinity epibatidine binding of functional, human α7-nicotinic acetylcholine receptors stably and heterologously expressed de novo in human SH-EP1 cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 1, 2005, Pages 24-35

  Peng, Jian Hong ^a   Fryer, John D ^a,d   Hurst, Raymond S ^b   Schroeder, Katherine M ^a,e   George, Andrew A ^a,f   Morrissy, Steven ^a,g   Groppi, Vincent E ^b   Leonard, Sherry S ^c   Lukas, Ronald J ^a  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d WASHINGTON UNIVERSITY   (United States)

^e NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^f UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^g UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; ALPHA BUNGAROTOXIN; BUNGAROTOXIN RECEPTOR; CARBACHOL; CYTISINE; EPIBATIDINE; IODINE 125; METHYLLYCACONITINE; NICOTINE; NICOTINIC RECEPTOR; RADIOLIGAND; RECEPTOR SUBUNIT; TUBOCURARINE CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CELL LINE; CELL STRAIN SH EP1; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; EPITHELIUM CELL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AUTORADIOGRAPHY; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOTTING, NORTHERN; BLOTTING, WESTERN; BUNGAROTOXINS; CELL LINE; CELL LINE, TUMOR; DNA, COMPLEMENTARY; EPITHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MEMBRANE POTENTIALS; NICOTINE; NICOTINIC AGONISTS; PATCH-CLAMP TECHNIQUES; PLASMIDS; PYRIDINES; RECEPTORS, NICOTINIC; RNA; TRANSFECTION;

EID: 15744382275     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.079004     Document Type: Article

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