The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression

Neuropsychopharmacology

Volumn 30, Issue 4, 2005, Pages 775-785

  Roiser, Jonathan P ^a   McLean, Andrew ^b   Ogilvie, Alan D ^c   Blackwell, Andrew D ^a   Bamber, Diane J ^d   Goodyer, Ian ^d   Jones, Peter B ^a   Sahakian, Barbara J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d Section of Developmental Psychiatry   (United Kingdom)

Author keywords

Acute phenylalanine and tyrosine depletion; Anhedonia; Decision making; Depression; Dopamine; Emotional processing; Reward punishment processing

Indexed keywords

AMINO ACID; NORADRENALIN; PHENYLALANINE; PLACEBO; SEROTONIN; TYROSINE;

ACUTE PHENYLALANINE AND TYROSINE DEPLETION; ADULT; ANHEDONIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; COMPREHENSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEPRESSION; DIET RESTRICTION; DOPAMINE METABOLISM; DOUBLE BLIND PROCEDURE; DRINKING; EMOTION; FEMALE; HAMILTON SCALE; HUMAN; HYPOTHESIS; MALE; MEDICAL DECISION MAKING; MENTAL INSTABILITY; NEUROPSYCHOLOGICAL TEST; PATHOLOGICAL GAMBLING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN FUNCTION; PUNISHMENT; RELAPSE; REWARD; SENSITIVITY ANALYSIS; STATISTICAL SIGNIFICANCE; SYMPTOM; TREATMENT OUTCOME; VALIDATION PROCESS;

ADULT; AMINO ACIDS, NEUTRAL; BRAIN; COGNITION DISORDERS; CROSS-OVER STUDIES; DECISION MAKING; DEPRESSIVE DISORDER; DOPAMINE; DOUBLE-BLIND METHOD; FEMALE; FOOD, FORMULATED; GAMBLING; HUMANS; JUDGMENT; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PHENYLALANINE; RECOVERY OF FUNCTION; REWARD; TYROSINE;

EID: 15444374947     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300659     Document Type: Article

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