Enantioselective reduction of β-keto acids with engineered streptomyces coelicolor

Angewandte Chemie - International Edition

Volumn 44, Issue 7, 2005, Pages 1121-1125

  Booker Milburn, Kevin I ^a   Gillan, Rebecca ^a   Kimberley, Meriel ^a   Taguchi, Takaaki ^b   Ichinose, Koji ^b,e   Richard Stephenson, G ^c   Ebizuka, Yutaka ^b   Hopwood, David A ^d  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d JOHN INNES CENTRE   (United Kingdom)

^e MUSASHINO UNIVERSITY   (Japan)

Author keywords

Bioorganic chemistry; Biosynthesis; Enantioselectivity; Enzymes; Reduction

Indexed keywords

ANTIBIOTIC ACTINORHODIN; ENANTIOSELECTIVE REDUCTION; ENZYME-BOUND THIOLATE;

ANTIBIOTICS; BIOSYNTHESIS; CELLS; ENZYMES; REDUCTION; STRAIN;

ORGANIC ACIDS;

ACTINORHODINE; ANTIBIOTIC AGENT; HYDROXYACID; OXOACID;

ARTICLE; BIOTRANSFORMATION; CELL TRANSFORMATION; ENANTIOSELECTIVITY; ENZYME BINDING; NONHUMAN; REDUCTION KINETICS; STRAIN IDENTIFICATION; STREPTOMYCES COELICOLOR; SYNTHESIS;

BACTERIAL PROTEINS; GENETIC ENGINEERING; KETO ACIDS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; OXIDOREDUCTASES; STEREOISOMERISM; STREPTOMYCES COELICOLOR;

EID: 15444374158     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200462076     Document Type: Article

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