Synthesis and pharmacological activity of triazolo[1,5-α]triazine derivatives inhibiting eosinophilia

Journal of Medicinal Chemistry

Volumn 41, Issue 16, 1998, Pages 2985-2993

  Akahoshi, Fumihiko ^a   Takeda, Shinji ^a   Okada, Takehiro ^a,b   Kajii, Masahiko ^a   Nishimura, Hiroko ^a   Sugiura, Masanori ^a,c   Inoue, Yoshihisa ^a   Fukaya, Chikara ^a   Naito, Youichiro ^a   Imagawa, Takashi ^a   Nakamura, Norifumi ^a  

^a Pharmaceutical Research Division   (Japan)

^b NIPPON ROCHE RESEARCH CENTER   (Japan)

^c Astra Japan Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 CHLOROPHENYL) 6 METHYL 1,2,4 TRIAZOLO[1,5 A] 1,3,5 TRIAZINE 7(6H)THIONE; 5 AMINO 3 (4 CHLOROPHENYL) 1 [(METHYLAMINO)THIOCARBONYL] 1H 1,2,4 TRIAZOLE; TRIAZINE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; EOSINOPHILIA; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-ASTHMATIC AGENTS; ANTIGENS, HELMINTH; ASCARIS; ASTHMA; CELL COUNT; DEXTRANS; DRUG EVALUATION, PRECLINICAL; EOSINOPHILS; GUINEA PIGS; HUMANS; MALE; PULMONARY EOSINOPHILIA; RESPIRATORY HYPERSENSITIVITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES; TRIAZOLES;

EID: 15444350800     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970759u     Document Type: Article

References (14)

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