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Volumn 6, Issue 5, 2003, Pages 511-517

Measuring in vivo metabolism using heavy water

Author keywords

2H2O; Biochemical flux; Metabolic regulation; Stable isotopes

Indexed keywords

DEUTERIUM OXIDE; GLUCOSE; GLYCOGEN; DIAGNOSTIC AGENT; DNA; PROTEIN;

EID: 1542781443     PISSN: 13631950     EISSN: None     Source Type: Journal    
DOI: 10.1097/00075197-200309000-00004     Document Type: Review
Times cited : (51)

References (36)
  • 1
    • 0000042369 scopus 로고
    • The study of intermediary metabolism of animals with the aid of isotopes
    • Schoenheimer R, Rittenberg D. The study of intermediary metabolism of animals with the aid of isotopes. Physiol Rev 1940; 20:218-248.
    • (1940) Physiol Rev , vol.20 , pp. 218-248
    • Schoenheimer, R.1    Rittenberg, D.2
  • 2
    • 0000677433 scopus 로고
    • The basis of the pharmacological action of heavy water in mammals
    • Barbour HG. The basis of the pharmacological action of heavy water in mammals. Yale J Biol Med 1936-1937; 9:551-565.
    • (1936) Yale J Biol Med , vol.9 , pp. 551-565
    • Barbour, H.G.1
  • 3
    • 18844458652 scopus 로고
    • Studies of metabolic turnover with tritium as a tracer. III. Comparative studies with tritium and deuterium
    • Thompson RC, Ballou JE. Studies of metabolic turnover with tritium as a tracer. III. Comparative studies with tritium and deuterium. J Biol Chem 1954; 206:101-107.
    • (1954) J Biol Chem , vol.206 , pp. 101-107
    • Thompson, R.C.1    Ballou, J.E.2
  • 4
    • 18844379515 scopus 로고
    • Studies of metabolic turnover with tritium as a tracer. IV. Metabolically inert lipide and protein fractions from the rat
    • Thompson RC, Ballou JE. Studies of metabolic turnover with tritium as a tracer. IV. Metabolically inert lipide and protein fractions from the rat. J Biol Chem 1954; 208:883-888.
    • (1954) J Biol Chem , vol.208 , pp. 883-888
    • Thompson, R.C.1    Ballou, J.E.2
  • 6
    • 0032079888 scopus 로고    scopus 로고
    • 3]acetone and gas chromatography-mass spectrometry
    • 3]acetone and gas chromatography-mass spectrometry. Anal Biochem 1998; 258:315-321.
    • (1998) Anal Biochem , vol.258 , pp. 315-321
    • Yang, D.1    Diraison, F.2    Beylot, M.3
  • 7
    • 0016230080 scopus 로고
    • Glucose synthesis in tritiated water
    • Rognstad R, Clark DG, Katz J. Glucose synthesis in tritiated water. Eur J Biochem 1974; 47:383-388.
    • (1974) Eur J Biochem , vol.47 , pp. 383-388
    • Rognstad, R.1    Clark, D.G.2    Katz, J.3
  • 11
    • 18844433966 scopus 로고
    • The glycogen-formation in the liver, studied by means of heavy hydrogen
    • Ussing HH. The glycogen-formation in the liver, studied by means of heavy hydrogen. Scand Arch Physiol 1937; 77:85-86.
    • (1937) Scand Arch Physiol , vol.77 , pp. 85-86
    • Ussing, H.H.1
  • 12
    • 0019126975 scopus 로고
    • The use of tritiated water to measure absolute rates of hepatic glycogen synthesis
    • Postle AD, Bloxham DP. The use of tritiated water to measure absolute rates of hepatic glycogen synthesis. Biochem J 1980; 192:65-73.
    • (1980) Biochem J , vol.192 , pp. 65-73
    • Postle, A.D.1    Bloxham, D.P.2
  • 13
    • 0013162158 scopus 로고
    • Deuterium as an indicator in the study of intermediary metabolism. VI. Synthesis and degradation of fatty acids in the organism
    • Schoenheimer R, Rittenberg D. Deuterium as an indicator in the study of intermediary metabolism. VI. Synthesis and degradation of fatty acids in the organism. J Biol Chem 1936; 114:381-396.
    • (1936) J Biol Chem , vol.114 , pp. 381-396
    • Schoenheimer, R.1    Rittenberg, D.2
  • 14
    • 0001364206 scopus 로고
    • Deuterium as an indicator in the study of intermediary metabolism IV. The mechanism of coprosterol formation
    • Schoenheimer R, Rittenberg D, Graff M. Deuterium as an indicator in the study of intermediary metabolism IV. The mechanism of coprosterol formation. J Biol Chem 1935; 111:183-192.
    • (1935) J Biol Chem , vol.111 , pp. 183-192
    • Schoenheimer, R.1    Rittenberg, D.2    Graff, M.3
  • 15
    • 18844364823 scopus 로고
    • Deuterium as an indicator in the study of intermediary metabolism XV. Further studies in coprosterol formation. The use of compounds containing labile deuterium for biological experiments
    • Anchel M, Schoenheimer R. Deuterium as an indicator in the study of intermediary metabolism XV. Further studies in coprosterol formation. The use of compounds containing labile deuterium for biological experiments. J Biol Chem 1985; 125:23-31.
    • (1985) J Biol Chem , vol.125 , pp. 23-31
    • Anchel, M.1    Schoenheimer, R.2
  • 16
    • 0014340534 scopus 로고
    • Fatty acid synthesis in adipose tissue incubated in tritiated water
    • Jungas RL. Fatty acid synthesis in adipose tissue incubated in tritiated water. Biochemistry 1968; 7:3708-3717.
    • (1968) Biochemistry , vol.7 , pp. 3708-3717
    • Jungas, R.L.1
  • 17
    • 0015849255 scopus 로고
    • Fatty acid synthesis by liver perfused with deuterated and tritiated water
    • Wadke M, Brunengraber H, Lowenstein JM, et al. Fatty acid synthesis by liver perfused with deuterated and tritiated water. Biochemistry 1973; 12:2619-2624.
    • (1973) Biochemistry , vol.12 , pp. 2619-2624
    • Wadke, M.1    Brunengraber, H.2    Lowenstein, J.M.3
  • 19
    • 0031033070 scopus 로고    scopus 로고
    • Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: Use of simple gas chromatography/mass spectrometric techniques
    • Diraison F, Pachiaudi C, Beylot M. Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: use of simple gas chromatography/mass spectrometric techniques. J Mass Spectrosc 1997; 32:81-86.
    • (1997) J Mass Spectrosc , vol.32 , pp. 81-86
    • Diraison, F.1    Pachiaudi, C.2    Beylot, M.3
  • 20
    • 0029836892 scopus 로고    scopus 로고
    • Tracing lipogenesis in humans using deuterated water
    • Jones PJ. Tracing lipogenesis in humans using deuterated water. Can J Physiol Pharmacol 1996; 74:755-760.
    • (1996) Can J Physiol Pharmacol , vol.74 , pp. 755-760
    • Jones, P.J.1
  • 22
    • 0032929228 scopus 로고    scopus 로고
    • Brown adipose tissue triacylglycerol synthesis in rats adapted to a high-protein, carbohydrate-free diet
    • Brito MN, Brito NA, Brito SR, et al. Brown adipose tissue triacylglycerol synthesis in rats adapted to a high-protein, carbohydrate-free diet. Am J Physiol 1999; 276:R1003-R1009.
    • (1999) Am J Physiol , vol.276
    • Brito, M.N.1    Brito, N.A.2    Brito, S.R.3
  • 23
    • 84964102419 scopus 로고
    • Synthesis of protein and amino acids in mice with the aid of deuterium
    • Stekol JA, Hamill WH. Synthesis of protein and amino acids in mice with the aid of deuterium. Proc Soc Exp Biol Med 1937; 35:591-593.
    • (1937) Proc Soc Exp Biol Med , vol.35 , pp. 591-593
    • Stekol, J.A.1    Hamill, W.H.2
  • 24
    • 0742313571 scopus 로고
    • Deuterium as an indicator in the study of intermediary metabolism: XIV. Biological formation of deuteroamino acids
    • Foster GL, Rittenberg D, Schoenheimer R. Deuterium as an indicator in the study of intermediary metabolism: XIV. Biological formation of deuteroamino acids. J Biol Chem 1938; 125:12-22.
    • (1938) J Biol Chem , vol.125 , pp. 12-22
    • Foster, G.L.1    Rittenberg, D.2    Schoenheimer, R.3
  • 25
    • 84979132359 scopus 로고
    • The rate of protein renewal in mice and rats studied by means of heavy hydrogen
    • Ussing HH. The rate of protein renewal in mice and rats studied by means of heavy hydrogen. Acta Physiol Scand 1941; 2:209-221.
    • (1941) Acta Physiol Scand , vol.2 , pp. 209-221
    • Ussing, H.H.1
  • 26
    • 0016782243 scopus 로고
    • A new method for the measurement of protein turnover
    • Humphrey TJ, Davies DD. A new method for the measurement of protein turnover. Biochem J 1975; 148:119-127.
    • (1975) Biochem J , vol.148 , pp. 119-127
    • Humphrey, T.J.1    Davies, D.D.2
  • 28
    • 0021518714 scopus 로고
    • Alanine kinetics in humans: Influence of different isotopic tracers
    • Yang RD, Matthews DE, Bier DM, et al. Alanine kinetics in humans: influence of different isotopic tracers. Am J Physiol Endocrinol Metab 1984; 247:E634-E638.
    • (1984) Am J Physiol Endocrinol Metab , vol.247
    • Yang, R.D.1    Matthews, D.E.2    Bier, D.M.3
  • 30
    • 18844417783 scopus 로고    scopus 로고
    • 2O for estimating protein synthesis and protein breakdown in vivo
    • 617.9
    • 2O for estimating protein synthesis and protein breakdown in vivo [abstract]. Faseb J 2002; 16:A788 (617.9).
    • (2002) Faseb J , vol.16
    • Previs, S.F.1
  • 32
    • 0035892726 scopus 로고    scopus 로고
    • Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation
    • Neese RA, Siler SQ, Cesar D, et al. Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation. Anal Biochem 2001; 298:189-195.
    • (2001) Anal Biochem , vol.298 , pp. 189-195
    • Neese, R.A.1    Siler, S.Q.2    Cesar, D.3
  • 34
    • 0037840686 scopus 로고    scopus 로고
    • Measurement of mitochondrial DNA synthesis in vivo in rodents and humans using a stable isotope-mass spectrometric technique
    • e published ahead of print
    • Collins ML, Eng S, Rebeccah H, Hellerstein MK. Measurement of mitochondrial DNA synthesis in vivo in rodents and humans using a stable isotope-mass spectrometric technique. J Appl Physiol 2003; 31: (e published ahead of print).
    • (2003) J Appl Physiol , vol.31
    • Collins, M.L.1    Eng, S.2    Rebeccah, H.3    Hellerstein, M.K.4
  • 35
    • 0043272776 scopus 로고    scopus 로고
    • 2O incorporation into TG-glycerol and application of mass isotopomer distribution analysis
    • 361.9
    • 2O incorporation into TG-glycerol and application of mass isotopomer distribution analysis [abstract]. Faseb J 2002; 16:A400 (361.9).
    • (2002) Faseb J , vol.16
    • Turner, S.M.1    Neese, R.A.2    Murphy, E.3
  • 36
    • 0041403652 scopus 로고    scopus 로고
    • 2O incorporation into non-essential amino acids and application of mass isotopomer distribution analysis
    • 212.7
    • 2O incorporation into non-essential amino acids and application of mass isotopomer distribution analysis [abstract]. Faseb J 2002; 16:A256 (212.7).
    • (2002) Faseb J , vol.16
    • Hellerstein, M.K.1    Neese, R.A.2    Kim, Y.-K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.