Anti-Ro/SSA and anti-La/SSB autoantibodies in the tear fluid of patients with Sjögren's syndrome

British Journal of Ophthalmology

Volumn 88, Issue 3, 2004, Pages 384-387

  Toker, E ^a,b   Yavuz, S ^b   Direskeneli, H ^b  

^a Inonu C Yildiz S   (Turkey)

^b MARMARA UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

LA ANTIGEN; RO ANTIBODY; ROSE BENGAL;

ADULT; AGED; ANTIBODY DETECTION; ARTICLE; ASSOCIATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DRY EYE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL DESIGN; EYE; FEMALE; HUMAN; KERATOCONJUNCTIVITIS SICCA; LACRIMAL FLUID; MEDICAL ASSESSMENT; PATIENT SELECTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PURIFICATION; QUANTITATIVE ANALYSIS; SCHIRMER TEST; SCORING SYSTEM; SJOEGREN SYNDROME; STAINING; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SYMPTOM; TITRIMETRY;

ADULT; AGED; ANTIBODIES, ANTINUCLEAR; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; HUMANS; IMMUNOGLOBULIN G; MIDDLE AGED; SJOGREN'S SYNDROME; STATISTICS, NONPARAMETRIC; TEARS;

EID: 1542721639     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2003.028340     Document Type: Article

References (30)

1. Chan EK, Tan EM. Epitopic targets for autoantibodies in SLE and Sjögren's syndrome. Curr Opin Rheumatol 1989;1:376-81.
2. Ben-Chetrit E, Gandy BJ, Tan EM, et al. Isolation and characterization of cDNA clone encoding the 60 kD component of the human SS-A/Ro ribonucleoprotein autoantigen. J Clin Invest 1989;83:1284-92.
3. O'Brien CA, Margelot K, Wolin SE. Xenopus Ro ribonucleoproteins: members of an evolutionary conserved class of cytoplasmic ribonucleoproteins. Proc Natl Acad Sci U S A 1993;90:7250-4.
4. Ben-Chetrit E, Chan EK, Sullivan KF, et al. A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. J Exp Med 1988;167:1560-71.
5. Boire G, Gendron M, Monast N, et al. Purification of antigenically intact Ro ribonucleoproteins: biochemical and immunological evidence that the 52-kD protein is not a Ro protein. Clin Exp Immunol 1995;100:489-98.
6. Kelekar A, Saitta MR, Keene JD. Molecular composition of Ro small ribonucleoprotein complexes in human cells-intracellular localization of the 60-and 52-kD proteins. J Clin Invest 1994;93:1637-44.
7. O'Brien CA, Wolin SL. A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S RNA precursors. Gene Dev 1994;8:2891-903.
8. Rinke J, Steitz JA. Precursor molecules of both human 5S ribosomal RNA and ransfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies. Cell 1982;29:149-59.
9. Gottlieb E, Steitz JA. Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. EMBO J 1989;8:851-61.
10. Stefano JE. Purified lupus antigen La recognizes an oligo uridylate stretch common to the 3′ termini of RNA polymerase III transcripts. Cell 1984;36:145-54.
11. Vitali C, Bombardieri S, Moutsopaulos HM, et al. Preliminary criteria for the classification of Sjögren's syndrome. Arthritis Rheum 1993;36:340-7.
12. Tan EM. Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv Immunol 1989;44:93-106.
13. Horsfall AC, Rose LM, Maini RN. Autoantibody synthesis in the salivary glands of Sjögren's syndrome patients. J Autoimmun 1989;2:559-68.
14. Ben-Chetrit E, Fischel R, Rubinow A. Anti-SSA/Ro and anti-SSB/La antibodies in serum and saliva of patients with Sjögren's syndrome. Clin Rheumatol 1993;12:471-4.
15. Halse A-K, Marthinussen MC, Wahren-Herlenius M, et al. Isotype distribution of anti-Ro/SS-A and anti-La/SS-B antibodies in plasma and saliva of patients with Sjögren's syndrome. Scan J Rheumatol 2000;29:13-19.
16. Tegner P, Halse A-K, Haga H-J, et al. Detection of anti-Ro/SSA and anti-La/ SSB autoantibody producing cells in salivary glands from patients with Sjögren's syndrome. Arthritis Rhem 1998;41:2238-48.
17. Halse A-K, Harley JB, Kroneld U, et al. Ro/SS-A reactive B lymphocytes in salivary glands and peripheral blood of patients with Sjögren's syndrome. Clin Exp Immunol 1999;115:203-7.
18. Bijsterveld O, Holland U. Diagnostic tests in sicca syndrome. Arch Ophthalmol 1969;82:10-14.
19. Alpspaugh MA, Talal N, Tan EM. Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum 1976;19:216-22.
20. Lindstrom FD, Eriksson P, Tejle K, et al. IgG subclasses of anti-SS-A/Ro in patients with primary Sjögren's syndrome. Clin Immunol Immunopathol 1994;73:358-361.
21. Wahren M, Ringertz NR, Pettersson I. IgM and IgG subclass distribution of human anti-Ro/SSA 60 kDa autoantibodies. Scand J Immunol 1994;39:179-83.
22. Pourmand N, Wahren-Herlenius M, Gunnarsson I, et al. Ro/SSA and La/SSB specific IgA antibodies in serum of patients with Sjögren's syndrome and systemic lupus erythematosus. Ann Rheum Dis 1999;58:623-9.
23. Domingo I, Coll J, Montobio J, et al. Lacrimal immunoglobulins in rheumatoid arthritis patients with or without Sjögren's syndrome. Ophthalmologica 1998;212:30-3.
24. Harley JB, Alexander EL, Bias WB, et al. Anti-Ro(SS-A) and anti-La(SS-B) in patients with Sjögren's syndrome. Arthritis Rheum 1986;29:196-206.
25. Hendrick JP, Wolin SL, Rinke J, et al. Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol Cell Biol 1981;1:1138-49.
26. Boire G, Craft J. Human Ro ribonucleoprotein particles: characterization of native structure and stable association with the La polypeptide. J Clin Invest 1990;85:1182-90.
27. Manoussakis MN, Tzioufas AG, Pange PJ, et al. Serologic profiles in subgroups of patients with Sjögren's syndrome. Scan J Rheumatol Suppl 1986;61:89-92.
28. Alexander EL, Arnett FC, Provost TT, et al. Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperactivity. Ann Intern Med 1983;98:155-9.
29. Gerli R, Muscat C, Giansanti M, et al. Quantitative assessment of salivary gland inflammatory infiltration in primary Sjögren's syndrome: its relationship to different demographic, clinical and serological features of the disorder. Br J Rheumatol 1997;36:969-75.
30. Nakamura S, Ikebe-Hiroki A, Shinohara M, et al. An association between salivary gland disease and serological abnormalities in Sjögren's syndrome. J Oral Pathol Med 1997;26:426-30.