Cell cycle and cell size regulation in Down Syndrome cells

Journal of Neural Transmission, Supplement

Volumn , Issue 67, 2003, Pages 51-58

  Rosner, M ^a   Kowalska, A ^a   Freilinger, A ^a   Prusa, A R ^a   Marton, E ^a   Hengstschlager M ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

AMNIOTIC FLUID CELL; ARTICLE; CELL CYCLE PHASE; CELL SIZE; CELLULAR DISTRIBUTION; CHROMOSOME 21; DOWN SYNDROME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; KARYOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; TRISOMY 21;

EID: 1542614441     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6721-2_4     Document Type: Article

References (20)

1. Antonarakis SE, Avramopoulos D, Blouin JL, Talbot CC, Schinzel AA (1993) Mitotic errors in somatic cells cause trisomy 21 in about 4.5% of cases and are not associated with maternal age. Nat Genet 3: 146-149
2. Arendt T (2002) Dysregulation of neuronal differentiation and cell cycle control in Alzheimer's disease. J Neural Transm [Suppl] 62: 77-85
3. Bernert G, Nemethova M, Herrera-Marschitz M, Cairns N, Lubec G (1996) Decreased cyclin dependent kinase in brain of patients with Down Syndrome. Neurosci Lett 216: 68-70
4. Cairns NJ (1999) Neuropathology. J Neural Transm [Suppl] 57: 61-74
5. Capone GT (2001) Down syndrome: advances in molecular biology and the neurosciences. Dev Behav Ped 22: 40-59
6. Engidawork E, Lubec G (2003) Molecular changes in fetal Down syndrome brain. J Neurochem 84: 895-904
7. Hengstschläger M, Braun K, Soucek T, Miloloza A, Hengstschläger-Ottnad E (1999a) Cyclin-dependent kinases at the G1-S transition of the mammalian cell cycle. Rev Mutat Res 436: 1-9
8. Hengstschläger M, Hölzl G, Hengstschläger-Ottnad E (1999b) Different regulation of c-Myc-and E2F-1-induced apoptosis during the ongoing cell cycle. Oncogene 18: 843-848
9. Hernandez D, Fisher EMC (1996) Down syndrome genetics: unravelling a multifactorial disorder. Hum Mol Genet 5: 1411-1416
10. Kligman D, Hilt CD (1988) The S100 protein family. Trends Biochem Sci 13: 437-443
11. Lubec G, Engidawork E (2002) The brain in Down syndrome (TRISOMY 21). J Neurol 249: 1347-1356
12. Nurse P (1975) Genetic control of cell size at cell division in yeast. Nature 256: 547-551
13. Pardee AB (1974) A restriction point for control of normal animal proliferation. Proc Natl Acad Sci USA 71: 1286-1290
14. Prusa A-R, Hengstschläger M (2002) Amniotic fluid cells and human stem cell research - a new connection. Med Sci Monit 8: 253-257
15. Pusch O, Bernaschek G, Eilers M, Hengstschläger M (1997) Activation of c-Myc uncouples DNA replication from activation of G1-cyclin-dependent kinases. Oncogene 15: 649-656
16. Soucek T, Rosner M, Miloloza A, Kubista M, Cheadle J, Sampson J, Hengstschläger M (2001) Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression. Oncogene 20: 4904-4909
17. Vidal-Taboada J, Lu A, Pique M, Pons G, Gil J, Oliva R (2000) Down Syndrome critical region gene 2: expression during mouse development and in human cell lines indicates a function related to cell proliferation. Biochem Biophys Res Com 272: 156-163
18. Wegner R-D (1999) Diagnostic cytogenetics. Springer, Berlin Heidelberg New York Tokyo
19. Yoon PW, Freeman SB, Sherman SL, Taft LF, Gu Y, Pettay D, Flanders WD, Khoury MJ, Hassold TJ (1996) Advanced maternal age and the risk of Down syndrome characterized by the meiotic stage of the chromosomal error: a population-based study. Am J Hum Genet 58: 628-633
20. Zetterberg A, Larsson O, Wiman KG (1995) What is the restriction point? Curr Opin Cell Biol 7: 835-842