Monoclonal antibody (3G5)-defined ganglioside: Cell surface marker of corneal keratocytes

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 3, 2004, Pages 807-812

  Stramer, Brian M ^a,c   Kwok, Michael G K ^c   Farthing Nayak, Pamela J ^a,b,c   Jung, Jae Chang ^a,c,e   Fini, M Elizabeth ^a,c,d   Nayak, Ramesh C ^a,b,c,f  

^a TUFTS MEDICAL CENTER   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e Kyungpook National University   (South Korea)

^f UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CELL SURFACE MARKER; GANGLIOSIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3G5; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MEMBRANE ANTIGEN; SIALOGANGLIOSIDES;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CATTLE; CORNEA CELL; CORNEA EPITHELIUM; CULTURE MEDIUM; ENDOTHELIUM; FROZEN SECTION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RABBIT; RAT; SWINE; TISSUE CULTURE; WOUND HEALING; ANIMAL; CORNEA STROMA; CYTOLOGY; FIBROBLAST; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; METABOLISM; MIDDLE AGED;

ADULT; AGED; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, SURFACE; BIOLOGICAL MARKERS; CATTLE; CORNEAL STROMA; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GANGLIOSIDES; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; RABBITS; RATS; SWINE;

EID: 1542532044     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0256     Document Type: Article

References (27)

1. Fini ME. Keratocyte and fibroblast phenotypes in the repairing cornea. Prog Retin Eye Res. 1999;18:529-551.
2. Nakayasu K, Hayashi N, Okisaka S, Sato N. Formation of capillary-like tubes by vascular endothelial cells co-cultivated with keratocytes. Invest Ophthalmol Vis Sci. 1992;33:3050-3057.
3. Nayak RC, Berman AB, George KL, Eisenbarth GS, King GL. A monoclonal antibody (3G5)-defined ganglioside antigen is expressed on the cell surface of microvascular pericytes. J Exp Med. 1988;167:1003-1015.
4. Nayak RC, Attawia MA, Cahill CJ, et al. Expression of a monoclonal antibody (3G5) defined ganglioside antigen in the renal cortex. Kidney Int. 1992;41:1638-1645.
5. Rabinowe SL, Nayak RC, Krisch K, George KL, Eisenbarth GS. Aging in man: linear increase of a novel T cell subset defined by antiganglioside monoclonal antibody 3G5. J Exp Med. 1987;165: 1436-1441.
6. Nayak RC, Colman PG, Eisenbarth GS. How are monoclonal antibodies related to autoimmune serology? Baillieres Clin Immunol Allergy. 1987;1:81-99.
7. Curatolo W. Glycolipid function. Biochim Biophys Acta. 1987; 906:137-160.
8. Nguyen M, Strubel NA, Bischoff JA. Role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis. Nature. 1993;365: 267-269.
9. Curatolo W. The physical properties of glycolipids. Biochim Biophys Acta. 1987;906:111-136.
10. Cintron C, Schneider H, Kublin C. Corneal scar formation. Exp Eye Res. 1973;17:251-259.
11. Matsubara M, Girard MT, Kublin CL, Cintron C, Fini ME. Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodelling cornea. Dev Biol. 1991;147:425-439.
12. Helmbold P, Wohlrab J, Marsch WC, Nayak RC. Human dermal pericytes express 3G5 ganglioside: a new approach for microvessel histology in the skin. J Cutan Pathol. 2001;28:206-210.
13. Nayak RC, Omar MA, Rabizadeh A, Srikanta S, Eisenbarth GS. "Cytoplasmic" islet cell antibodies: evidence that the target antigen is a sialoglycoconjugate. Diabetes. 1985;34:617-619.
14. Helmbold P, Nayak RC, Holzhausen HJ, Marsch WC, Herman IM. Isolation of human dermal microvascular pericytes and identification in culture. Microvasc Res. 2001;61:160-165.
15. Corpuz LM, Funderburgh JL, Funderburgh ML, et al. Molecular cloning and tissue distribution of keratocan: bovine corneal keratan sulfate proteoglycan 37A. J Biol Chem. 1996;271:9759-9763.
16. Tasheva ES, Funderburgh JL, Corpuz LM, Conrad GW. Cloning, characterization and tissue-specific expression of the gene encoding bovine keratocan, a corneal keratan sulfate proteoglycan. Gene. 1998;218:63-68.
17. Toti P, Tosi GM, Traversi C, et al. CD-34 stromal expression pattern in normal and altered human corneas. Ophthalmology. 2002;109: 1167-1171.
18. Jester JV, Huang J, Petroll WM, Cavanagh HD. TGFbeta induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGFbeta, PDGF and integrin signaling. Exp Eye Res. 2002; 75:645-657.
19. Jester JV, Petroll WM, Barry PA, Cavanagh HD. Expression of alpha-smooth muscle (alpha-SM) actin during corneal stromal wound healing. Invest Ophthalmol Vis Sci. 1995;36:809-819.
20. Stramer BM, Zieske JD, Jung JC, Austin JS, Fini ME. Molecular mechanisms controlling the fibrotic repair phenotype in cornea: implications for surgical outcomes. Invest Ophthalmol Vis Sci. 2003;44:4237-4246.
21. Beales MP, Funderburgh JL, Jester JV, Hassell JR. Proteoglycan synthesis by bovine keratocytes and corneal fibroblasts: maintenance of the keratocyte phenotype in culture. Invest Ophthalmol Vis Sci. 1999;40:1658-1663.
22. Berryhill BL, Kader R, Kane B, et al. Partial restoration of the keratocyte phenotype to bovine keratocytes made fibroblastic by serum. Invest Ophthalmol Vis Sci. 2002;43:3416-3421.
23. Jester JV, Barry-Lane PA, Petroll WM, Olsen DR, Cavanagh HD. Inhibition of corneal fibrosis by topical application of blocking antibodies to TGF beta in the rabbit. Cornea. 1997;16:177-187.
24. Moller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Neutralizing antibody to TGFbeta modulates stromal fibrosis but not regression of photoablative effect following PRK. Curr Eye Res. 1998;17:736-747.
25. Moller-Pedersen T, Li, HF, Petroll WM, Cavanagh HD, Jester JV. Confocal microscopic characterization of wound repair after photorefractive keratectomy. Invest Ophthalmol Vis Sci. 1998;39: 487-501.
26. Moller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Stromal wound healing explains refractive instability and haze development after photorefractive keratectomy: a 1-year confocal microscopic study. Ophthalmology. 2000;107:1235-1245.
27. Jester JV, Moller-Pedersen T, Huang J, et al. The cellular basis of corneal transparency: evidence for "corneal crystallins". J Cell Sci. 1999;112:613-622.