Rationalizing the Structural Properties of Bupivacaine Base - A Local Anesthetic - Directly from Powder X-ray Diffraction Data

Journal of Pharmaceutical Sciences

Volumn 93, Issue 3, 2004, Pages 667-674

  Cheung, Eugene Y ^a   Harris, Kenneth D M ^a   Johnston, Roy L ^a   Kitchin, Simon J ^a   Hadden, Kelly L ^b   Zakrzewski, Marek ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b PURDUE PHARMA L P   (United States)

Author keywords

Bupivacaine base; Local anesthetic effects; Powder X ray diffraction data

Indexed keywords

2',6' PIPECOLOXYLIDIDE DERIVATIVE; BUPIVACAINE; PIPECOLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ACTION POTENTIAL; ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; GENETIC ALGORITHM; LOCAL ANESTHESIA; RIETVELD REFINEMENT; STRUCTURE ACTIVITY RELATION; X RAY POWDER DIFFRACTION;

EID: 1542515179     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10551     Document Type: Article

References (20)

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