Simultaneous production of homoanatoxin-a, anatoxin-a, and a new non-toxic 4-hydroxyhomoanatoxin-a by the cyanobacterium Raphidiopsis mediterranea Skuja

Toxicon

Volumn 42, Issue 5, 2003, Pages 533-538

  Namikoshi, Michio ^a   Murakami, Tomokazu ^a   Watanabe, Mariyo F ^b   Oda, Taiko ^c   Yamada, Junko ^c   Tsujimura, Shigeo ^d   Nagai, Hiroshi ^a   Oishi, Shinshi ^e  

^a TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

^b RISSHO UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d LAKE BIWA ENVIRONMENTAL RESEARCH INSTITUTE   (Japan)

^e TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

4 Hydroxyhomoanatoxin a; Anatoxin a; Cyanobacterium; Homoanatoxin a; Neurotoxin; Raphidiopsis mediterranea

Indexed keywords

4 HYDROXYHOMOANATOXIN A; ANATOXIN A; BACTERIAL TOXIN; HOMOANATOXIN A; METHANOL; NEUROTOXIN; UNCLASSIFIED DRUG; WATER; 4-HYDROXYHOMOANATOXIN-A; CELL EXTRACT; CYANOBACTERIAL TOXIN; CYANOGINOSIN; HOMOANATOXIN-A; MARINE TOXIN;

ADSORPTION; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CYANOBACTERIUM; ELUTION; EVAPORATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION PROCEDURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; RAPHIDIOPSIS MEDITERRANEA; SEPARATION TECHNIQUE; STRUCTURE ANALYSIS; TOXIN ANALYSIS; TOXIN STRUCTURE; ANIMAL; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; INSTITUTE FOR CANCER RESEARCH MOUSE; INTRAPERITONEAL DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; LD 50;

RAPHIDIOPSIS MEDITERRANEA;

ANIMALS; BACTERIAL TOXINS; CELL EXTRACTS; CYANOBACTERIA; INJECTIONS, INTRAPERITONEAL; LETHAL DOSE 50; MALE; MARINE TOXINS; MICE; MICE, INBRED ICR; MICROCYSTINS; MOLECULAR STRUCTURE; NEUROTOXINS;

EID: 1542496610     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(03)00233-2     Document Type: Article

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