Bioavailability of granulocyte colony-stimulating factor administered enterally to suckling mice

Pharmacological Research

Volumn 48, Issue 6, 2003, Pages 643-647

  Gersting, Jason A ^a   Kotto Kome, Catherine A ^b   Du, Yan ^a   Christensen, Robert D ^b   Calhoun, Darlene A ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

EGF; Epidermal growth factor; Epo; Erythropoietin; G CSF; G CSF R; Gastrointestinal; GI; Granulocyte colony stimulating factor; Granulocyte colony stimulating factor receptor; IGF; Insulin like growth factor; KO

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL EXPERIMENT; ARTICLE; CIRCULATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ADMINISTRATION ROUTE; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; GASTROINTESTINAL TRACT; GENE MUTATION; GENE TARGETING; HEMOCONCENTRATION; MEASUREMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SUCKLING; SWALLOWING;

AGE FACTORS; ANIMALS; ANIMALS, SUCKLING; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; ENTERAL NUTRITION; FEMALE; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR;

EID: 1542397742     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-6618(03)00249-4     Document Type: Article

References (33)

1. Clapp J., Little K., Appleby-Wineberg S., Widness J. The effect of regular maternal exercise on erythropoietin in cord blood and amniotic fluid. Am. J. Obstet. Gynecol. 172:1995;1445-1451.
2. Letterio J., Geiser A., Kulkarni A., Roche N., Sporn M., Roberts A. Maternal rescue of transforming growth factor-B1 null mice. Science. 264:1994;1936-1938.
3. Berseth C.L. Enhancement of intestinal growth in neonatal rats by epidermal growth factor in milk. Am. J. Physiol. 253(5 Pt 1):1987;662-665.
4. Kling P., Sullivan T., Roberts R., Phillips A., Koldovsky O. Human milk as a potential enteral source of erythropoietin. Pediatr. Res. 43:1998;216-221.
5. Macias C., Schweigert F.J. Changes in the concentration of carotenoids, Vitamin A, alpha-tocopherol and total lipids in human milk throughout early lactation. Ann. Nutr. Metab. 45(2):2001;82-85.
6. Stewart C.J., Iles R.K., Perrett D. The analysis of human amniotic fluid using capillary electrophoresis. Electrophoresis. 22(6):2001;1136-1142.
7. Calhoun D.A., Chegini N., Polliotti B.M., Gersting J.A., Miller R.K., Christensen R.D. Granulocyte colony-stimulating factor in preterm and term pregnancy, parturition, and intra-amniotic infection. Obstet. Gynecol. 97(2):2001;229-234.
8. Calhoun DA, Lunøe M, Du Y, Christensen RD. Granulocyte colony-stimulating factor (G-CSF) is present in human milk and its receptor (G-CSF-R) is present in human fetal intestine. Pediatrics 2000;105(1). Available at: http://www.pediatrics.org/cgi/content/full/105/1/e7.
9. Avalos B. Molecular analysis of the granulocyte colony-stimulating factor receptor. Blood. 88:1996;761-777.
10. Saito S., Fukunaga R., Ichijo M., Nagata S. Expression of granulocyte colony-stimulating factor and its receptor at the fetomaternal interface in murine and human pregnancy. Growth Factors. 10:1994;135-143.
11. Calhoun D.A., Richards B., Gersting J.A., Sullivan S., Christensen R.D. G-CSF and erythropoietin stability in amniotic fluid during simulated in vitro digestion conditions. J. Pharm. Technol. 18(6):2002;310-315.
12. Calhoun D.A., Lunøe M., Du Y., Staba S., Christensen R.D. Concentrations of granulocyte colony-stimulating factor in human milk after in vitro simulations of digestion. Pediatr. Res. 46:1999;767-771.
13. Baumrucker C.R., Hadsell D.L., Blum J.W. Effects of dietary insulin-like growth factor I on growth and insulin-like growth factor receptors in neonatal calf intestine. J. Anim. Sci. 72(2):1994;428-433.
14. Buhler C., Hammon H., Rossi G.L., Blum J.W. Small intestinal morphology in eight-day-old calves fed colostrum for different durations or only milk replacer and treated with long-R3-insulin-like growth factor I and growth hormone. J. Anim. Sci. 76(3):1998;758-765.
15. Houle V.M., Schroeder E.A., Odle J., Donovan S.M. Small intestinal disaccharidase activity and ileal villus height are increased in piglets consuming formula containing recombinant human insulin-like growth factor-I. Pediatr. Res. 42(1):1997;78-86.
16. Koldovsky O. Hormones in milk. Vitam. Horm. 50:1995;77-149.
17. Koldovsky O. The potential physiological significance of milk-borne hormonal active substances for the neonate. J. Mammary Gland Biol. Neoplasia. 1:1996;317-323.
18. Koldovsky O. Hormonally active peptides in human milk. Acta Paediatr. Suppl. 402:1994;89-93.
19. Dvorak B., Williams C.S., McWilliam D.L., Shinohara H., Dominguez J.A., McCuskey R.S.et al. Milk-borne epidermal growth factor modulates intestinal transforming growth factor-alpha levels in neonatal rats. Pediatr. Res. 47(2):2000;194-200.
20. Juul S.E., Zhao Y., Dame J.B., Du Y., Hutson A.D., Christensen R.D. Origin and fate of erythropoietin in human milk. Pediatr. Res. 48(5):2000;660-667.
21. Odle J., Zijlstra R.T., Donovan S.M. Intestinal effects of milkborne growth factors in neonates of agricultural importance. J. Anim. Sci. 74(10):1996;2509-2522.
22. Calhoun D.A., Maheshwari A., Christensen R.D. Recombinant granulocyte colony-stimulating factor administered enterally to neonates is not absorbed. Pediatrics. 112(2):2003;421-423.
23. Liu F., Wu H., Wesselschmidt R., Kornaga T., Link D. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor deficient mice. Immunity. 5:1996;491-501.
24. Ekstrom G.M., Westrom B.R. Intestinal uptake and transmission of macromolecules into the blood in the young guinea pig. J. Pediatr. Gastroenterol. Nutr. 14(1):1992;71-78.
25. Klein R.M., McKenzie J.C. Pattern of crypt cell proliferation in the pre- and post-closure ileum of the neonatal rat: effects of sympathectomy. Cell Tissue Res. 206(3):1980;387-394.
26. Takada K., Tohyama Y., Oohashi M., Yoshikawa H., Muranishi S., Shimosaka A.et al. Is recombinant human granulocyte colony-stimulating factor (G-CSF) orally available in rats? Chem. Pharm. Bull. (Tokyo). 37:1989;838-839.
27. Jensen-Pippo K.E., Whitcomb K.L., De Prince R.B., Ralph L., Habberfield A.D. Enteral bioavailability of human granulocyte colony stimulating factor conjugated with poly(ethylene glycol). Pharm. Res. 13:1996;102-107.
28. Burrin D.G., Wester T.J., Davis T.A., Amick S., Heath J.P. Orally administered IGF-I increases intestinal mucosal growth in formula-fed neonatal pigs. Am. J. Physiol. 270(5 Pt 2):1996;1085-1091.
29. Kimble R.M., Breier B.H., Gluckman P.D., Harding J.E. Enteral IGF-I enhances fetal growth and gastrointestinal development in oesophageal ligated fetal sheep. J. Endocrinol. 162(2):1999;227-235.
30. Pollack P.F., Goda T., Colony P.C., Edmond J., Thornburg W., Korc M.et al. Effects of enterally fed epidermal growth factor on the small and large intestine of the suckling rat. Regul. Pept. 17(3):1987;121-132.
31. Miller-Gilbert A.L., Dubuque S.H., Dvorak B., Williams C.S., Grille J., Woodward S.S.et al. Enteral absorption of erythropoietin in the suckling rat. Pediatr. Res. 50:2001;261-267.
32. Okamoto C.T. Endocytosis and transcytosis. Adv. Drug Deliv. Rev. 29(3):1998;215-228.
33. Smart E.J., Ying Y., Donzell W.C., Anderson R.G. A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane. J. Biol. Chem. 271(46):1996;29427-29435.