Higher Vessel Densities in Retinoblastoma with Local Invasive Growth and Metastasis

American Journal of Pathology

Volumn 164, Issue 2, 2004, Pages 391-394

  Rössler, Jochen ^a,b   Dietrich, Torsten ^a   Pavlakovic, Helena ^a,c   Schweigerer, Lothar ^a,c   Havers, Werner ^a   Schüler, Andreas ^a   Bornfeld, Norbert ^a   Schilling, Harald ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CD31 ANTIBODY; UNCLASSIFIED DRUG; CD31 ANTIGEN;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTIBODY DETECTION; ARTICLE; CANCER GROWTH; CANCER INVASION; CHOROID; CLINICAL FEATURE; CORRELATION ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; METASTASIS; OPTIC NERVE; PRIORITY JOURNAL; RETINOBLASTOMA; RETROSPECTIVE STUDY; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; INFANT; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; RETINA TUMOR; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANTIGENS, CD31; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; RETINAL NEOPLASMS; RETINOBLASTOMA; RETROSPECTIVE STUDIES;

EID: 1542379768     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63129-X     Document Type: Article

References (25)

1. Kock E, Naeser P: Retinoblastoma in Sweden 1958-1971: a clinical and histopathological study. Acta Ophthalmol Copenh 1979, 57:344-350
2. Mahoney MC, Burnett WS, Majerovics A, Tanenbaum H: The epidemiology of ophthalmic malignancies in New York State. Ophthalmology 1990, 97:1143-1147
3. Sanders BM, Draper GJ, Kingston JE: Retinoblastoma in Great Britain 1969-80: incidence, treatment, and survival. Br J Ophthalmol 1988, 72:576-583
4. Hinds PW: The retinoblastoma tumor suppressor protein. Curr Opin Genet Dev 1995, 5:79-83
5. Tso MOM, Zimmermann LE, Fine BS: The nature of retinoblastoma II: photoreceptor differentiation: an electron microscopy study. Am J Ophthalmol 1970, 69:350-359
6. Bornfeld N, Schüler A, Bechrakis N, Henze G, Havers W: Preliminary results of primary chemotherapy in retinoblastoma. Klin Pädiatr 1997, 209:216-221
7. Messmer EP, Heinrich T, Hopping W, de Sutter E, Havers W, Sauerwein W: Risk factors for metastasis in patients with retinoblastoma. Ophthalmology 1991, 99:136-141
8. Shields C, Shields JA, Baez KA, Cater J, De Potter PV: Choroldal invasion of retinoblastoma: metastatic potential and clinical risk factors. Br J Ophthalmol 1993, 77:544-548
9. Shields C: Optic nerve invasion of retinoblastoma: metastatic potential and clinical risk factor. Cancer 1994, 73:692-698
10. Folkman J, Watson K, Ingber D, Hanahan D: Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989, 339:58-61
11. Folkman J: Seminars in medicine of the Beth Israel Hospital, Boston: clinical applications of research on angiogenesis. N Engl J Med 1995, 333:1757-1763
12. Fox SB, Leek RD, Bliss J, Mansi JL, Gusterson B, Gatter KC, Harris AL: Association of tumor angiogenesis with bone marrow micrometastases in breast cancer patient. J Natl Cancer Inst 1997, 89:1044-1049
13. Tanigawa N, Amaya H, Matsumura M, Lu C, Kitaoka A, Matsuyama K, Muraoka R: Tumor angiogenesis and mode of metastasis in patients with colorectal cancer. Cancer Res 1997, 57:1043-1046
14. Meitar D, Crawford SE, Rademaker AW, Cohn SL: Tumor angiogenesis correlates with metastatic disease, N-myc amplification and poor outcome in human neuroblastoma. J Clin Oncol 1996, 14:405-414
15. Foss AJE, Alexander RA, Jefferies LW, Hungerford JL, Harris AL, Lightman S: Microvessel count predicts survival in uveal melanoma. Cancer Res 1996, 56:2900-2903
16. Pe'er J, Neufeld M, Baras M, Gnessin H, Itin A, Keshet E: Rubeosis iridis in retinoblastoma: histologic findings and the possible role of vascular endothelial growth factor in its induction. Ophthalmology 1997, 104:1251-1258
17. Schweigerer L, Neufeld G, Gospodarowicz D: Basic fibroblast growthfactor is present in cultured human retinoblastoma cells. Invest Ophthalmol Vis Sci 1987, 28:1838-1843
18. Vermeulen PB, Gasparini G, Fox SB, Toi M, Martin L, McCulloch P, Pezzella F, Viale G, Weidner N, Harris AL, Dirix LY: Quantification of angiogenesis in solid human tumors: an international consensus on the methodology and criteria of evaluation. Eur J Cancer 1996, 14:2474-2484
19. Höpping W, Havers W, Passarge E: Retinoblastom. Pädiatrie in Praxis und Klinik. Edited by KD Bachmann. New York. Georg Thieme Verlag, Gustav Fischer Verlag, 1988, pp 755-770
20. Olver J, McCartney ACE, Kingston J, Hungerford J: Histological indicators of the prognosis for survival following enucleation for retinoblastoma. Tumors of the Eye. Edited by N Bornfeld, ES Gragoudas, W Höpping, PK Lommatzsch. New York: Kugler, 1991, pp 59-67
21. Saleh R, Gross S, Cassano W, Gee A: Metastatic retinoblastoma successfully treated with immunomagnetic purged autologous bone marrow transplantation. Cancer 1988, 62:2301-2303
22. Sandri A, Besenzon L, Acquaviva A, Marino C, Cordero di Montezemolo L, Madon E: "Eight drugs in one day" chemotherapy in a nonfamilial bilateral retinoblastoma with recurrent cerebrospinal fluid metastasis. Pediatr Hematol Oncol 1998, 15:557-561
23. Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86:353-364
24. Schweigerer L: Anti-angiogenesis as a novel therapeutic concept in pediatric oncology. J Mol Med 1995, 73:497-508
25. Pavlakovic H, Havers W, Schweigerer L: Multiple angiogenesis stimulators in a single malignancy. Angiogenesis 2001, 4:259-262