Suppression of Macrophage Eicosanoid Synthesis by Atherogenic Lipoproteins Is Profoundly Affected by Cholesterol-Fatty Acyl Esterification and the Niemann-Pick C Pathway of Lipid Trafficking

Journal of Biological Chemistry

Volumn 279, Issue 9, 2004, Pages 8084-8092

  Leventhal, Andrew R ^a   Leslie, Christina C ^b   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; ENZYMES; FATTY ACIDS; LIPIDS; PROTEINS;

ENDOSOMES; LIPOPROTEINS;

BIOCHEMISTRY;

ACYL COENZYME A; CHOLESTEROL; LEUKOTRIENE C4; LIPOPROTEIN; PROSTAGLANDIN E2; VESICULAR TRANSPORT PROTEIN;

ANIMAL CELL; ARTICLE; ATHEROGENESIS; ATHEROMA; ATHEROSCLEROSIS; ENDOPLASMIC RETICULUM; ENDOSOME; ESTERIFICATION; FATTY ACID METABOLISM; ICOSANOID METABOLISM; INTERNALIZATION; LIPID METABOLISM; LIPID TRANSPORT; MACROPHAGE ACTIVATION; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANDROSTENES; ANIMALS; ARTERIOSCLEROSIS; CALCIMYCIN; CHOLESTEROL; DINOPROSTONE; EICOSANOIDS; ENDOPLASMIC RETICULUM; ENDOSOMES; ENZYME INHIBITORS; ESTERIFICATION; FATTY ACIDS; HUMANS; LEUKOTRIENES; LIPOPROTEINS; LIPOPROTEINS, LDL; LYSOSOMES; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MUTATION; NIEMANN-PICK DISEASES; PHOSPHOLIPASES A; PHOSPHOLIPIDS; PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STEROL O-ACYLTRANSFERASE;

ANIMALIA;

EID: 1542379664     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310672200     Document Type: Article

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