Replacement of 198MQMDII203 of mouse IRF-1 by 197IPVEVV202 of human IRF-1 abrogates induction of IFN-β, iNOS, and COX-2 gene expression by IRF-1

Biochemical and Biophysical Research Communications

Volumn 314, Issue 3, 2004, Pages 737-744

  Upreti, Meenakshi ^a   Kumar, Sanjiv ^a   Rath, Pramod C ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

COX 2; iNOS; Interferon ; IRF 1; Transactivation domain

Indexed keywords

BETA INTERFERON; CYCLOOXYGENASE 2; DNA; HYBRID PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; RECOMBINANT PROTEIN; DNA BINDING PROTEIN; IRF1 PROTEIN, HUMAN; IRF1 PROTEIN, MOUSE; ISOENZYME; MEMBRANE PROTEIN; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; NOS2A PROTEIN, HUMAN; PHOSPHOPROTEIN; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHROMOSOME; CONTROLLED STUDY; DNA BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; TRANSCRIPTION INITIATION; WILD TYPE; AMINO ACID SUBSTITUTION; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

MURINAE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CYCLOOXYGENASE 2; DNA; DNA-BINDING PROTEINS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-BETA; ISOENZYMES; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOPROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANSFECTION;

EID: 1542376901     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.12.156     Document Type: Article

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