S-Nitrosothiols in the Blood: Roles, Amounts, and Methods of Analysis

Circulation Research

Volumn 94, Issue 4, 2004, Pages 414-417

  Stamler, Jonathan S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Nitric oxide; S nitrosothiols; Vasodilation

Indexed keywords

ALBUMIN; CERULOPLASMIN; CYSTEINE; ERYTHROCYTE BAND 3 PROTEIN; HEMOGLOBIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; S NITROSOALBUMIN; S NITROSOGLUTHATIONE; S NITROSOHEMOGLOBIN; S NITROSOTHIOL; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

DIABETES MELLITUS; EDITORIAL; ERYTHROCYTE MEMBRANE; HEART FAILURE; HYDROGEN BOND; NITROSYLATION; OXIDATIVE STRESS; OXYGEN SATURATION; OXYGEN TENSION; PRIORITY JOURNAL; SHOCK; VASOCONSTRICTION; VASODILATATION;

FORECASTING; HEMOGLOBINS; HUMANS; MODELS, BIOLOGICAL; NITRIC OXIDE; NITROSO COMPOUNDS; OXIDATION-REDUCTION; OXYGEN; REFERENCE STANDARDS; S-NITROSOGLUTATHIONE; SERUM ALBUMIN, BOVINE; SULFHYDRYL COMPOUNDS; SUPEROXIDES; VASODILATION;

EID: 1542373633     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000122071.55721.BC     Document Type: Editorial

References (31)

1. Stamler JS, Simon DI, Osborne JA, Mullins ME. Jaraki O, Michel T, Singel DJ, Loscalzo J. S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. Proc Natl Acad Sci U S A. 1992;89:444-448.
2. Stamler JS, Jaraki O, Osborne J, Simon DI, Keaney J, Vita J, Singel D, Valeri CR, Loscalzo J. Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci U S A. 1992;89:7674-7677.
3. Gaston B, Reilly J, Drazen JM, Fackler J, Ramdev P, Arnelle D, Mullins ME, Sugarbaker DJ, Chee C, Singel DJ, Loscalzo J, Stamler JS. Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways. Proc Natl Acad Sci U S A. 1993;90:10957-10961.
4. Jia L, Bonaventura C, Bonaventura J, Stamler JS. S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control. Nature. 1996; 380:221-226.
5. Pawloski JR, Hess DT, Stamler JS. Export by red blood cells of nitric oxide bioactivity. Nature. 2001;409:622-626.
6. McMahon TJ, Moon RE, Luschinger BP, Carraway MS, Stone AE, Stolp BW, Gow AJ, Pawloski JR, Watke P, Singel DJ, Piantadosi CA, Stamler JS. Nitric oxide in the human respiratory cycle. Nat Med. 2002;8: 711-717.
7. Datta B, Tufnell-Barrett T, Bleasdale R, Jones C, Beeton I, Paul V, Frenneaux M, James P. Red blood cell nitric oxide as an endocrine vasoregulator: a potential role in congestive heart failure. Circulation. In press.
8. Foster MW, McMahon TJ, Stamler JS. S-nitrosylation in health and disease. Trends Mol Med. 2003;9:160-168.
9. Rafikova O, Rafikov R, Nudler E. Catalysis of S-nitrosothiols formation by serum albumin: the mechanism and implication in vascular control. Proc Natl Acad Sci U S A. 2002;99:5913-5918.
10. Gow AJ, Stamler JS. Reactions between nitric oxide and haemoglobin under physiological conditions. Nature. 1998;391:169-173.
11. Gow AJ, Luchsinger BP, Pawloski JR, Singel DJ, Stamlef JS. The oxyhemoglobin reaction of nitric oxide. Proc Natl Acad Sci U S A. 1999; 96:9027-9032.
12. Luchsinger BP, Rich EN, Gow AJ, Williams EM, Stamler JS, Singel DJ. Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the beta subunits. Proc Natl Acad Sci U S A. 2003; 100:461-466.
13. Romeo AA, Capobianco JA, English AM. Superoxide dismutase targets NO from GSNO to Cysβ93 of oxyhemoglobin in concentrated but not dilute solutions of the protein. J Am Chem Soc. 2003;125:14370-14378.
14. Inoue K, Akaike T, Miyamoto Y, Okamoto T, Sawa T, Otagiri M, Suzuki S, Yoshimura T, Maeda H. Nitrosothiol formation catalyzed by ceruloplasmin: implication for cytoprotective mechanism in vivo. J Biol Chem. 1999;274:27069-27075.
15. -. Free Radic Biol Med. 2003;34:1078-1088.
16. Ng ESM, Jourd'heuil D, McCord JM, Hernandez D, Yasui M, Knight D, Kubes P. Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion. Circ Res. 2004;94:559-565.
17. Hallstrom S, Gasser H, Neumayer C, Fugl A, Nanobashvili J, Jakubowski A, Huk I, Schlag G, Malinski T. S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release. Circulation. 2002;105:3032-3038.
18. Tyurin VA, Liu SX, Tyurina YY, Sussman NB, Hubel CA, Roberts JM, Taylor RN, Kagan VE. Elevated levels of S-nitrosoalbumin in preeclampsia plasma. Circ Res. 2001;88:1210-1215.
19. Simon DI, Mullins ME, Jia L, Gaston B, Singel DJ, Stamler JS. Polynitrosylated proteins: characterization, bioactivity, and functional consequences. Proc Natl Acad Sci U S A. 1996;93:4736-4741.
20. 13N]nitric oxide: a positron emission tomography (PET) study. Nucl Med Biol. 1996;23:773-777.
21. Napoli C, Aldini G, Wallace JL, de Nigris F, Maffei R, Abete P, Bonaduce D, Condorelli G, Rengo F, Sica V, D'Armiento FP, Mignogna C, de Rosa G, Condorelli M, Lerman LO, Ignarro LJ. Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis. Proc Natl Acad Sci U S A. 2002;99:1689-1694.
22. Kirima K, Tsuchiya K, Sei H, Hasegawa T, Shikishima M, Motobayashi Y, Morita K, Yoshizumi M, Tamaki T. Evaluation of systemic blood NO dynamics by EPR spectroscopy: HbNO as an endogenous index of NO. Am J Physiol Heart Circ Physiol. 2003;285:H589-H596.
23. Cannon RO 3rd, Schechter AN, Panza JA, Ognibene FP, Pease-Fye ME, Waclawiw MA, Shelhamer JH, Gladwin MT. Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery. J Clin Invest. 2001;108:279-287.
24. Milsom AB, Jones CJ, Goodfellow J, Frenneaux MP, Peters JR, James PE. Abnormal metabolic fate of nitric oxide in type I diabetes mellitus. Diabetologia. 2002;45:1515-1522.
25. Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, Yang BK, Waclawiw MA, Zalos G, Xu X, Huang KT, Shields H, Kim-Shapiro DB, Schechter AN, Cannon RO 3rd, Gladwin MT. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med. 2003;9:1498-1505.
26. Rassaf T, Bryan NS, Maloney RE, Specian V, Kelm M, Kalyanaraman B, Rodriguez J, Feelisch M. NO adducts in mammalian red blood cells: too much or too little? Nat Med. 2003;9:481-482; author reply 482-483.
27. Stamler JS, Toone EJ. The decomposition of thionitrites. Curr Opin Chem Biol. 2002;6:779-785.
28. Chan NL, Kavanaugh JS, Rogers PH, Arnone A. Crystallographic analysis of the interaction of nitric oxide with quatemary-T human hemoglobin. Biochemistry. 2004;43:118-132.
29. Nagababu E, Ramasamy S, Abernethy DR, Rifkind JM. Active nitric oxide produced in the red cell under hypoxic conditions by deoxyhemoglobin-mediated nitrite reduction. J Biol Chem. 2003;278: 46349-46356.
30. Liu L, Yan Y, Zeng M, Zhang J, Hanes MA, Ahearn G, McMahon TJ, Dickfeld T, Marshall HE, Que LG, Stamler JS. Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell. 2004; 116:617-628.
31. Massy ZA, Fumeron C, Borderie D, Tuppin P, Nguyen-Khoa T, Benoit MO, Jacquot C, Buisson C, Drueke TB, Ekindjian OG, Lacour B, Iliou MC. Increased plasma S-nitrosothiol concentrations predict cardiovascular outcomes among patients with end-stage renal disease: a prospective study. J Am Soc Nephrol. 2004;15:470-476.