Use of Desferoxamine and S-Adenosylmethionine to Treat Hemochromatosis in A Red Ruffed Lemur (Varecia variegata ruber)

Comparative Medicine

Volumn 54, Issue 1, 2004, Pages 100-103

  Sanchez, Carlos R ^a   Murray, Suzan ^a   Montali, Richard J ^a  

^a SMITHSONIAN CONSERVATION BIOLOGY INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE; DEFEROXAMINE MESYLATE; DENOSYL; FERRITIN; IRON; S ADENOSYLMETHIONINE; TRANSFERRIN;

ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CAUSE OF DEATH; FERRITIN BLOOD LEVEL; HEMOCHROMATOSIS; IRON CHELATION; IRON STORAGE; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER FUNCTION; MALE; NONHUMAN; PHLEBOTOMY; PROSIMIAN; TRANSFERRIN BLOOD LEVEL;

ANIMALS; BLOOD CHEMICAL ANALYSIS; COMBINED MODALITY THERAPY; DEFEROXAMINE; FATAL OUTCOME; HEMATOLOGIC TESTS; HEMOCHROMATOSIS; IRON; IRON CHELATING AGENTS; LEMUR; LIVER; MALE; PHLEBOTOMY; PRIMATE DISEASES; REFERENCE VALUES; S-ADENOSYLMETHIONINE;

EID: 1542366335     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Barton, J. C., S. M. McDonnell, P. C. Adams, P. Brissot, L. W. Powell, C. Q. Edwards, J. D. Cook, and K. V. Kowdley. 1998. Management of hemochromatosis. Hemochormatosis management working group. Ann. Intern. Med. 129:932-939.
2. Bray, G. P., J. M. Tredger, and R. Williams. 1992. S-adenosylmethionine protects against acetaminophen toxicity in mice. Hepatology 15(2):297-301.
3. Brittenham, G. M., P. M. Griffith, A. Nienhuis, C. E. McLaren, N. S. Young, E. E. Tucker, C. J. Allen, D. E. Farrel, and J. W. Harris. 1994. Efficacy of desferoxamine in preventing complications of iron overload in patients with thalassemia major. N. Engl. J. Med. 331(9):567-573.
4. Center, S. A. 2000. S-adenosyl-methionine (SAMe) an antioxidant and anti-inflammatory nutraceutical. Proc. Am. Coll. Vet. Intern. Med. 18:550-552.
5. Center, S. A., J. F. Randolph, K. Warner, W. E. Hoffman, J. McCabe, and P. Foureman. 2000. Influence of SAMe on erythrocytes and liver tissue in healthy cats. Proc. Am. Coll. Vet. Intern. Med. 18:734.
6. Center, S. A., K. Warner, W. E. Hoffman, P. Foureman, and J. McCabe. 1999. Influence of S-adenosylmethionine on metabolic and morphologic hepatocellular features induced by chronic glucocorticoid administration in dogs. Proc. Am. Coll. Vet. Intern. Med. 17:719.
7. Cork, S. C. 2000. Iron storage diseases in birds. Avian Pathol. 29:7-12.
8. Cornelissen, H., R. Ducatelle, and S. Roels. 1995. Successful treatment of a channel-billed toucan (Ramphastos vitellinus) with iron storage disease by chelation therapy: sequential monitoring of the iron content of the liver during the treatment period by quantitative chemical and image analysis. J. Avian Med. Surg. 9:131-137.
9. Cornelius, C. E. 1988. Animal models, p. 1316-1336. In I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, and D. A. Shafritz (ed.), The liver. Biology and pathobiology, 2nd ed. Raven Press, New York.
10. Cumming, R. L. C., J. A. Millar, J. A. Smith, and A. Goldberg. 1969. Clinical and laboratory studies on the action of desferoxamine. Br. J. Haematol. 17:257-263.
11. Davidson, G. 2002. S-Adenosylmethionine. Compend. Contin. Educ. Pract. Vet. 24 (8):600-603.
12. Felitti, V. J. and E. Beutler. 1999. New developments in hereditary hemochromatosis. Am. J. Med. Sci. 318(4):257-268.
13. Franchini, M., G. Gandini, M. de Gironcoli, A. Vassanelli, C. Borgna-Pignatti, and G. Aprili. 2000. Safety and efficacy of subcutaneous bolus injection of desferoxamine in adult patients with iron overload. Blood. 95(9):2776-2779.
14. Frezza, M. and M. Terpin. 1992. The use of S-adenosyl-L-methionine in the treatment of cholestatic disorders. Drug Invest. 4(Suppl 4):101-108.
15. Gonzalez, J., K. B. Benirschke, P. Saltman, J. Roberts, and P. T. Robinson. 1984. Hemosiderosis in lemurs. Zoo Biol. 3:255-265.
16. Junge, R. E. 1997. Diseases of lemurs in captivity. Proc. Annu. Conf. Am. Assoc. Zoo Vet. Houston 1:235-239.
17. Junge, R. E. 1999. Diseases of prosimians, p. 365-368. In M. E. Fowler and R. E. Miller (ed.), Zoo and wild animal medicine, current therapy 4. W. B. Saunders Co., Philadelphia.
18. Kontoghiorghes, G. J., K. Pattichi, M. Hadjigavriel and A. Kolnagou. 2000. Transfusional iron overload and chelation therapy with desferoxamine and deferiprone (L1). Transfusion Sci. 23 (3):211-23.
19. Lieber, C. 2002. S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings. Alcohol. 27:173-177.
20. Lieber, C. S., A. Casini, L. DeCarli, C. Kim, N. Lowe, R. Sasaki, and M. A. Leo. 1990. S-Adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon. Hepatology. 11 (20):165-172.
21. Lowenstine, L. J., and L. Munson. 1999. Iron overload in the animal kingdom, p. 260-268. In M. E. Fowler, and R. E. Miller (ed.), Zoo and wild animal medicine, current therapy 4. W. B. Saunders Co., Philadelphia.
22. McClain, C. J., D. B. Hill, Z. Song, R. Chawla, W. H. Watson, T. Chen, and S. Barve. 2002. S-Adenosylmethionine, cytokines, and alcoholic liver disease. Alcohol 27:185-192.
23. Miller, G. F., D. E. Barnard, R. A. Woodward, B. M. Flynn, and J. W. M. Bulte. 1997. Hepatic hemosiderosis in common marmosets Callithrix jacchus: effect of diet on incidence and severity. Lab. Anim. Sci. 47:138-142.
24. Morris, P. J., S. E. Avergis, and R. E. Baumgartner. 1989. Hemochromatosis in a greater Indian hill mynah (Gracula religiosa): case report and review of the literature. J. Assoc. Avian Vet. 2:87-92.
25. Pearson, E. G., O. R. Hedstrom, and R. H. Poppega. 1994. Hepatic cirrhosis and hemochromatosis in three horses. J. Am. Vet. Med. Assoc. 204(7):1053-1056.
26. Porter, J. B. 2001. Desferoxamine pharmacokinetics. Semin. Hematol. 38(1):63-68.
27. Powell, L. W., D. K. George, S. M. McDonell, and K. V. Kowdley. 1998. Diagnosis of hemochromatosis. Ann. Intern. Med. 129(11):925-931.
28. Powell, L. W., E. C. Jazwinska, and J. W. Halliday. 1994. Primary iron overload, p. 227-270. In J. H. Brock, J. W. Halliday, M. J. Pippard, and L. W. Powell (ed.), Iron metabolism in health and diseases. W. B. Saunders Co., Philadelphia.
29. Powell, L. W. and K. J. Isselbacher. 1998. Hemochromatosis, p. 2149-2152. In A. S. Fauci, E. Braunwald, K. J. Isselbacher, J. D. Wilson, J. B. Martin, D. L. Kasper, S. L. Hauser, and D. L. Longo (ed.), Principles of internal medicine, 14th ed. McGraw-Hill, New York.
30. Sheppard, C. and E. Dierenfeld. 2002. Iron storage disease in birds: speculation on etiology and implications for captive husbandry. J. Avian Med. Surg. 16(3):192-197.
31. Spelman, L. H., K. G. Osborn, and M. P. Anderson. 1989. Pathogenesis of hemosiderosis in lemurs: role of dietary iron, tannin, and ascorbic acid. Zoo Biol. 8:239-251.
32. Stramentinoli, G. 1987. Pharmacologic aspects of S-adenosylmethionine. Am. J. Med. 83(suppl. 5A):35-42.
33. Tsai, S., K. Lee, and L. Tsai. 2001. Effects of S-Adenosyl-L-methionine on liver damage in experimental obstructive jaundice. Kaohsiung J. Med. Sci. 17:455-460.
34. Wood, C. 2002. Hemosiderosis and lemurs. Incidence, diagnosis, genetics and dietary prevention. Proc. XIX Congress Int. Primat. Soc. Beijing, China.
35. Worell, A. B. 1991. Phlebotomy for the treatment of hemochromatosis in two Sulfur-breasted toucans. Proc. Annu. Conf. Assoc. Avian Vet. 1:9-14.