In vitro induction of inhibitory macrophage differentiation by granulocyte-macrophage colony-stimulating factor, stem cell factor and interferon-gamma from lineage phenotypes-negative c-kit-positive murine hematopoietic progenitor cells

Immunology Letters

Volumn 91, Issue 2-3, 2004, Pages 221-227

  Ferret Bernard, Stéphanie ^a   Saï, Pierre ^a   Bach, Jean Marie ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

Hematopoietic progenitor cells; Inhibitory macrophages; Monocyte development; Nitric oxide

Indexed keywords

CD11B ANTIGEN; CD86 ANTIGEN; CYCLOPHOSPHAMIDE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CELL ACTIVITY; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DENDRITIC CELL; FEMALE; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; IMMUNOPHENOTYPING; INFECTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPPRESSOR CELL; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD11B; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; INTERFERON TYPE II; MACROPHAGES; MICE; MICE, INBRED BALB C; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-KIT; STEM CELL FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 1542362398     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2003.12.008     Document Type: Article

References (24)

1. Angulo I., Rodriguez R., Garcia B., Medina M., Navarro J., Subiza J.L. Involvement of nitric oxide in bone marrow-derived natural suppressor activity. Its dependence on IFN-gamma. J. Immunol. 155:1995;15-26.
2. Angulo I., de las Heras F.G., Garcia-Bustos J.F., Gargallo D., Munoz-Fernandez M.A., Fresno M. Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+) CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice. Blood. 95:2000;212-220.
3. Mazzoni A., Bronte V., Visintin A., Spitzer J.H., Apolloni E., Serafini P.et al. Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J. Immunol. 168:2002;689-695.
4. Bronte V., Wang M., Overwijk W.W., Surman D.R., Pericle F., Rosenberg S.A.et al. Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells. J. Immunol. 161:1998;5313-5320.
5. Apolloni E., Bronte V., Mazzoni A., Serafini P., Cabrelle A., Segal D.M.et al. Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes. J. Immunol. 165:2000;6723-6730.
6. Kusmartsev S.A., Li Y., Chen S.H. Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation. J. Immunol. 165:2000;779-785.
7. Bronte V., Serafini P., Apolloni E., Zanovello P. Tumor-induced immune dysfunctions caused by myeloid suppressor cells. J. Immunother. 24:2001;431-446.
8. Goñi O., Alcaide P., Fresno M. Immunosuppression during acute Trypanosoma cruzi infection: involvement of Ly6G (Gr1+)CD11b+ immature myeloid suppressor cells. Int. Immunol. 14:2002;1125-1134.
9. Bronte V., Apolloni E., Cabrelle A., Ronca R., Serafini P., Zamboni P.et al. Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood. 96:2000;3838-3846.
10. McCormack J.M., Leenen P.J., Walker W.S., Angulo I., Rodriguez R., Garcia B.et al. Macrophage progenitors from mouse bone marrow and spleen differ in their expression of the Ly-6C differentiation antigen through an IFN-gamma-dependent iNOS induction. J. Immunol. 151:1993;6389-6398.
11. Chan J., Leenen P.J., Bertoncello I., Nishikawa S.I., Hamilton J.A. Macrophage lineage cells in inflammation: characterization by colony-stimulating factor-1 (CSF-1) receptor (c-Fms), ER-MP58, and ER-MP20 (Ly-6C) expression. Blood. 92:1998;1423-1431.
12. Bronte V., Chappell D.B., Apolloni E., Cabrelle A., Wang M., Hwu P.et al. Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation. J. Immunol. 162:1999;5728-5737.
13. Krenger W., Falzarano G., Delmonte J., Snyder K.M., Byon J.C., Ferrara J.L. Interferon-gamma suppresses T-cell proliferation to mitogen via the nitric oxide pathway during experimental acute graft-versus-host disease. Blood. 88:1996;1113-1121.
14. MacMicking J., Xie Q.W., Nathan C. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:1997;323-350.
15. Witsell A.L., Schook L.B. Tumor necrosis factor alpha is an autocrine growth regulator during macrophage differentiation. Proc. Natl. Acad. Sci. U.S.A. 89:1992;4754-4758.
16. Winston B.W., Krein P.M., Mowat C., Huang Y. Cytokine-induced macrophage differentiation: a tale of 2 genes. Clin. Invest. Med. 22:1999;236-255.
17. Kraal G., Rep M., Janse M. Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical study. Scand. J. Immunol. 26:1987;653-661.
18. Zhang Y., Mukaida N., Wang J., Harada A., Akiyama M., Matsushima K. Induction of dendritic cell differentiation by granulocyte-macrophage colony-stimulating factor, stem cell factor, and tumor necrosis factor alpha in vitro from lineage phenotypes-negative c-kit+ murine hematopoietic progenitor cells. Blood. 90:1997;4842-4853.
19. Lowenstein C.J., Alley E.W., Raval P., Snowman A.M., Snyder S.H., Russell S.W.et al. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc. Natl. Acad. Sci. U.S.A. 90:1993;9730-9734.
20. Hanninen A., Jaakkola I., Salmi M., Simell O., Jalkanen S., Zhang Y.et al. Ly-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways. Proc. Natl. Acad. Sci. U.S.A. 94:1997;6898-6903.
21. de Bruijn M.F., Slieker W.A., van der Loo J.C., Voerman J.S., van Ewijk W., Leenen P.J. Distinct mouse bone marrow macrophage precursors identified by differential expression of ER-MP12 and ER-MP20 antigens. Eur. J. Immunol. 24:1994;2279-2284.
22. de Bruijn M.F., van Vianen W., Ploemacher R.E., Bakker-Woudenberg I.A., Campbell P.A., van Ewijk W.et al. Bone marrow cellular composition in Listeria monocytogenes infected mice detected using ER-MP12 and ER-MP20 antibodies: a flow cytometric alternative to differential counting. J. Immunol. Methods. 217:1998;27-39.
23. Jutila M.A., Kroese F.G., Jutila K.L., Stall A.M., Fiering S., Herzenberg L.A.et al. Ly-6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon-gamma. Eur. J. Immunol. 18:1988;1819-1826.
24. Salvadori S., Martinelli G., Zier K. Resection of solid tumors reverses T cell defects and restores protective immunity. J. Immunol. 164:2000;2214-2220.