Association between p53 Gene Mutations and Tobacco and Alcohol Exposure in Laryngeal Squamous Cell Carcinoma

Archives of Otolaryngology - Head and Neck Surgery

Volumn 130, Issue 3, 2004, Pages 303-306

  Ronchetti, Domenica ^a   Neglia, Cesare B ^a   Cesana, Bruno M ^a   Carboni, Nadia ^a   Neri, Antonino ^a   Pruneri, Giancarlo ^b   Pignataro, Lorenzo ^a,c  

^a UNIVERSITY OF MILAN   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; CONTROLLED STUDY; DNA BINDING MOTIF; EXON; FEMALE; GENE ACTIVITY; GENE MAPPING; GENE MUTATION; HUMAN; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; SINGLE STRAND CONFORMATION POLYMORPHISM; SMOKING HABIT; SQUAMOUS CELL CARCINOMA; TOBACCO; TUMOR SUPPRESSOR GENE;

ALCOHOL DRINKING; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; FEMALE; GENES, P53; HUMANS; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SMOKING;

EID: 1542348287     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.130.3.303     Document Type: Article

References (25)

1. Lowe SW, Ruley HE, Jacks T, et al. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993;74:957-967.
2. Stratton MR. The p53 gene in human cancer. Eur J Cancer. 1992;28:293-295
3. Brachman DG, Beckett M, Graves D, et al. p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res. 1993;53:3667-3669.
4. Boyle JO, Hakim J, Koch WM, et al. The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res. 1993;53:4817-4822.
5. Ahomadegbe JC, Barrois M, Fogel S. et al. High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases, absence of correlation with clinical outcome: frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene. 1995;10:1217-1227.
6. Field JK, Zoumpourlis V, Spandidos DA, Jones AS. p53 expression and mutations in squamous cell carcinoma of the head and neck: expression correlates with the patients' use of tobacco and alcohol. Cancer Detect Prev. 1994;18:197-208.
7. Koch WM, Brennan JA, Zahurak M, et al. p53 mutations in locoregional: treatment failure in head and neck squamous cell carcinoma. J Natl Cancer Inst. 1996;88:1580-1586.
8. Olshan AF, Weissler MC, Pei H, Conway K. p53 mutations in head and neck cancer new data and evaluation of mutational spectra. Cancer Epidemiol Biomarkers Prev. 1997;6:499-504.
9. Brennan JA, Boyle JO, Koch WM, et al. Association between cigarette smoking and mutation of the p53 gene in squamous cell carcinoma of the head and neck. N Engl J Med. 1995;332:712-717.
10. Koch WM, Lango M, Sewell D, Zahurak M, Sidransky D. Head and neck cancer in nonsmokers: a distinct clinical and molecular entity. Laryngoscope. 1999;109:1544-1551.
11. Zhang LF, Hemminki K, Szyfter K, Szyfter W, Soderkvist P. p53 mutations in larynx cancer. Carcinogenesis. 1994;15:2949-2951.
12. Sarkar FH, Sakr WA, Li YW, Jacobs J, Crissman JD. Tumor suppressor p53 gene mutation in squamous cell carcinoma of the larynx. Diagn Mol Pathol. 1996;5:201-205.
13. Cattaruzza MS, Maisonneuve P, Boyle P. Epidemiology of laryngeal cancer. Eur J Cancer B Oral Oncol. 1996;32B:293-305.
14. Flanders WD, Rothman KJ. Interaction of alcohol and tobacco in laryngeal cancer. Am J Epidemiol. 1982;115:371-379.
15. Pruneri G, Pignataro L, Fracchiolla NS, et al. p53 protein expression in laryngeal squamous cell carcinomas bearing wild-type and mutated p53 gene. Histopathology. 1996;28:513-519.
16. World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. Bull World Health Organ. 2001;79:373-374.
17. Armitage P, Berry G. Statistical Methods in Medical Research. London, England Blackwell Scientific Publications; 1987:125-132.
18. Kaplan EL, Meier P. Non parametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
19. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 1966;50:163-170.
20. Shanmugaratnam K, Sobin LH. Histological Typing of Tumours of the Upper Respiratory Tract and Ear. Geneva, Switzerland: World Health Organization; 1991.
21. Soussi T, Beroud C. Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer. 2001;1:233-240.
22. 23;265:346-355.
23. Denissenko M, Pao A, Tang M, Pfeifer GP. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53. Science. 1996;18:430-432.
24. Lazarus P, Stern J, Zwiebel N, Fair A, Richie JP Jr, Shantz S. Relationship between p53 mutation incidence in oral cavity squamous cell carcinomas and patient tobacco use. Carcinogenesis. 1996;17:733-739.
25. Assimakopoulos D, Kolettas E, Zagorianakou N. Prognostic significance of p53 in the cancer of the larynx. Anticancer Res. 2000;20:3555-3564.