Automated Modeling of Cardiac Electrical Activity

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 1, Issue , 2003, Pages 55-58

  Syed, Z F ^a   Vigmond, E ^a   Leon, L J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Action potential; Atrial cell; Automated modeling; Conductance parameters; Genetic algorithm

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; ERROR ANALYSIS; GENETIC ALGORITHMS; INTERPOLATION; IONIC CONDUCTION; ITERATIVE METHODS; MATHEMATICAL MODELS; PATHOLOGY;

ACTION POTENTIAL; ATRIAL CELLS; AUTOMATED MODELING; CONDUCTANCE PARAMETERS;

CARDIOLOGY;

EID: 1542333395     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (12)

1. Antzelevitch, C., Sicouri, S., Litovsky, S. H., Lukas, A., Krishnan, S.C., Di Diego, J. M., Gintant, G. A., and Liu D., "Heterogeneity Within the Ventricular Wall- Electrophysiology and Pharmacology of Epicardial, Endocardial, and M Cells", Circulation Research 1991; Vol 69, No 6:1427-1449
2. Liu, D., Gintant, G.A., Antzelevitch, C., "Ionic Basis for Electrophysiological Distinctions Among Epicardial, Midmyocardial, and Endocardial Myocytes From the Free Wall of the Canine Left Ventricle", Circulation Research 1993;72:671-687
3. Litovsky, S., Antzelevitch, C., "Transient Outward Current Prominent in Canine Ventricular Epicardium but Not Endocardium", Circulation Research 1988;62:116-126
4. k,s in Electrical Heterogeneity", American Journal of Physiology. 268 (Heart Circulation Physiology 37):H604-H613, 1995
5. Feng, Jianlin; Yue, Lixia; Wang, Zhiguo; Nattel, Stanley, "Ionic mechanisms of regional action potential heterogeneity in the canine right atrium".Circ Res. 1998 Sep 7;83(5):541-51.
6. Ramirez, R.J., Nattel, S., Courtemanche, M., "Mathematical Analysis of Canine Atrial Action Potentials: Rate, Regional Factors, and Electrical Remodeling", American Journal of Physiology (2000) Heart Circulation Physiology 279: H1767-H1785
7. Nygren, A., Leon, L. J., Giles, W. R., "Simulations of the human atrial action potential", Phil. Trans. R. Soc. Lond. A (2001) 359, 1111-1125
8. Hodgkin, A. L., Huxley, A. F., "A Quantitative Description of Membrane Current and Its Application To Conduction and Excitation In Nerve", Journal of Physiology (1952) 117, 500-544
9. + Currents in Repolarization", Circulation Research 1998; 82:63-81
10. Goldberg, D. E., "Genetic Algorithms in Search, Optimization, and Machine Learning", Addison Wesley Longman, Inc., 1989
11. Michalewicz, Z., "Genetic Algorithms + Data Structures = Evolution Programs", Springer-Verlag Berlin Heidelberg New York, 1996
12. Courtemanche, M., Rafael, J. R., Nattel, S., "Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model", American Journal of Physiology 275 (Heart Circ. Physiol. 44) 1998: H301-H321