메뉴 건너뛰기




Volumn 62, Issue 2471, 2004, Pages 443-449

Biologic therapies for autoimmune deseases;Intérêt des thérapies biologiques dans les maladies auto-immunes

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ALEFACEPT; BETA1A INTERFERON; CYTOKINE; CYTOKINE RECEPTOR; EFALIZUMAB; ETANERCEPT; IMMUNOMODULATING AGENT; INFLIXIMAB; INTERFERON BETA SERINE; INTERLEUKIN 1; MONOCLONAL ANTIBODY; NATALIZUMAB; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 1542328217     PISSN: 00256749     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (68)
  • 2
    • 0036333860 scopus 로고    scopus 로고
    • Autoreactive CD8 T cells in organ-specific autoimmunity: Emergency targets for therapeutic intervention
    • Liblau RS, Wong FS, Mars LT, Santamaria P. Autoreactive CD8 T cells in organ-specific autoimmunity: Emergency targets for therapeutic intervention. Immunity 2002; 17: 1-6.
    • (2002) Immunity , vol.17 , pp. 1-6
    • Liblau, R.S.1    Wong, F.S.2    Mars, L.T.3    Santamaria, P.4
  • 3
    • 0032754990 scopus 로고    scopus 로고
    • Cytokines that relate autoimmune responses
    • Falcone M, Sarvetnick N. Cytokines that relate autoimmune responses. Curr Opin Immunol 1999; 11: 670-6.
    • (1999) Curr Opin Immunol , vol.11 , pp. 670-676
    • Falcone, M.1    Sarvetnick, N.2
  • 4
    • 0035555366 scopus 로고    scopus 로고
    • Autoimmune diseases, genes, bugs and failed regulation
    • Ermann J, Fathman CG. Autoimmune diseases, genes, bugs and failed regulation. Nat Immunol 2001; 2: 802-19.
    • (2001) Nat Immunol , vol.2 , pp. 802-819
    • Ermann, J.1    Fathman, C.G.2
  • 5
    • 0026091413 scopus 로고
    • Localization of tumor necrosis facteur-α in synovial tissues and at the cartilage-pannus junction in patients with rhumatoïde arthritis
    • Chu CQ, Field M, Feldmann M, Maini RN. Localization of tumor necrosis facteur-α in synovial tissues and at the cartilage-pannus junction in patients with rhumatoïde arthritis. Arthritis Rheum 1991; 34: 1125-32.
    • (1991) Arthritis Rheum , vol.34 , pp. 1125-1132
    • Chu, C.Q.1    Field, M.2    Feldmann, M.3    Maini, R.N.4
  • 6
    • 0033708837 scopus 로고
    • Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α
    • Cenci S, Weitzmann MN, Foggia C, et al. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α. J Clin Invest 1993; 106: 1229-37.
    • (1993) J Clin Invest , vol.106 , pp. 1229-1237
    • Cenci, S.1    Weitzmann, M.N.2    Foggia, C.3
  • 7
    • 0025827590 scopus 로고
    • A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
    • Peppel K, Crawford D, Beutler B. A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J Exp Med 1991; 174: 1483-9.
    • (1991) J Exp Med , vol.174 , pp. 1483-1489
    • Peppel, K.1    Crawford, D.2    Beutler, B.3
  • 8
    • 0030996312 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-α therapy of rheumatoid arthritis
    • Feldmann M, Elliot M, Woody J, Maini R. Anti-tumor necrosis factor-α therapy of rheumatoid arthritis. Advances Immunol 1997; 64: 283-350.
    • (1997) Advances Immunol , vol.64 , pp. 283-350
    • Feldmann, M.1    Elliot, M.2    Woody, J.3    Maini, R.4
  • 9
    • 10744227300 scopus 로고    scopus 로고
    • Efficacy and safety of the fully human anti-tumor necrosis factor alpha monoclonal antibody adalimumab 8D2E7) in DMARD refractory patients with rheumatoid arthritis: A 12 week, phase II study
    • Van de Putte LB, Rau R, Breedveld FC, et al. Efficacy and safety of the fully human anti-tumor necrosis factor alpha monoclonal antibody adalimumab 8D2E7) in DMARD refractory patients with rheumatoid arthritis: A 12 week, phase II study. Ann Rheum Dis 2003; 62: 1168-77.
    • (2003) Ann Rheum Dis , vol.62 , pp. 1168-1177
    • Van De Putte, L.B.1    Rau, R.2    Breedveld, F.C.3
  • 10
    • 0034735827 scopus 로고    scopus 로고
    • A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis
    • Bathon JM, Martin RW, Fleischmann RM, et al. A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med 2000; 343: 1586-93.
    • (2000) N Engl J Med , vol.343 , pp. 1586-1593
    • Bathon, J.M.1    Martin, R.W.2    Fleischmann, R.M.3
  • 11
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis
    • Lipsky PE, Desiree MFM, van Der Heijde MD, et al. Infliximab and methotrexate in the treatment of rheumatoid arthritis. N Engl J Med 2000; 343: 1594-602.
    • (2000) N Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    Desiree, M.F.M.2    Van Der Heijde, M.D.3
  • 12
    • 0034673697 scopus 로고    scopus 로고
    • Etanercept in children with polyarticular juvenil rheumatoid arthritis
    • Pediatric Rheumatology Collaborative Study Group
    • Lovell DJ, Giannini EH, Reiff A, et al. Pediatric Rheumatology Collaborative Study Group. Etanercept in children with polyarticular juvenil rheumatoid arthritis. N Engl J Med 2000; 342: 763-9.
    • (2000) N Engl J Med , vol.342 , pp. 763-769
    • Lovell, D.J.1    Giannini, E.H.2    Reiff, A.3
  • 13
    • 0037231476 scopus 로고    scopus 로고
    • Long-term efficacy and safety of etanercept in children with polyarticular-course juvenile rheumatoid arthritis: Interim results from an ongoing multicenter, open-label, extended-treatment trial
    • Pediatric Rheumatology Collaborative Study Group
    • Lovell DJ, Giannini EH, Reiff A, et al. Pediatric Rheumatology Collaborative Study Group. Long-term efficacy and safety of etanercept in children with polyarticular-course juvenile rheumatoid arthritis: Interim results from an ongoing multicenter, open-label, extended-treatment trial. Arthritis Rheum 2003; 48: 218-26.
    • (2003) Arthritis Rheum , vol.48 , pp. 218-226
    • Lovell, D.J.1    Giannini, E.H.2    Reiff, A.3
  • 14
    • 0037370938 scopus 로고    scopus 로고
    • Infiximab or etanercept in the treatment of children with refractory juvenile idiopathic arthritis: An open label study
    • Lahdenne P, Vahasalo P, Honkanen V. Infiximab or etanercept in the treatment of children with refractory juvenile idiopathic arthritis: An open label study. Ann Rheum Dis 2003; 62: 245-7.
    • (2003) Ann Rheum Dis , vol.62 , pp. 245-247
    • Lahdenne, P.1    Vahasalo, P.2    Honkanen, V.3
  • 15
    • 14944347525 scopus 로고    scopus 로고
    • Efficacy of infusions of an antitumor necrosis factor a antibody (infliximab) in persistently active refractory juvenile idiopathic arthritis. Results of a two years open label prospective study
    • Abstract
    • Gerloni V, Lurati A, Gattinara M, et al. Efficacy of infusions of an antitumor necrosis factor a antibody (infliximab) in persistently active refractory juvenile idiopathic arthritis. Results of a two years open label prospective study. [Abstract] Arthritis Rheum 2003; 48 (Suppl. 9): S124.
    • (2003) Arthritis Rheum , vol.48 , Issue.SUPPL. 9
    • Gerloni, V.1    Lurati, A.2    Gattinara, M.3
  • 16
    • 0036093131 scopus 로고    scopus 로고
    • Etanercept in the treatment of adult patients with Still's disease
    • Husni ME, Maier AL, Mease PJ, et al. Etanercept in the treatment of adult patients with Still's disease. Arthritis Rheum 2002; 46: 1171-6.
    • (2002) Arthritis Rheum , vol.46 , pp. 1171-1176
    • Husni, M.E.1    Maier, A.L.2    Mease, P.J.3
  • 17
    • 0042072982 scopus 로고    scopus 로고
    • Long-term efficacy and safety of infliximab in the treatment of ankylosing spondylitis: An open, observational, extension study of a three-month, randomized, placebo-controlled trial
    • Braun J, Brandt J, Listing J, et al. Long-term efficacy and safety of infliximab in the treatment of ankylosing spondylitis: An open, observational, extension study of a three-month, randomized, placebo-controlled trial. Arthritis Rheum 2003; 48: 2224-33.
    • (2003) Arthritis Rheum , vol.48 , pp. 2224-2233
    • Braun, J.1    Brandt, J.2    Listing, J.3
  • 18
    • 0037007683 scopus 로고    scopus 로고
    • Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor α
    • Gorman JD, Sack KE, Davis JC. Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor α. N Engl J Med 2002; 346: 1349-56.
    • (2002) N Engl J Med , vol.346 , pp. 1349-1356
    • Gorman, J.D.1    Sack, K.E.2    Davis, J.C.3
  • 19
    • 0034729950 scopus 로고    scopus 로고
    • Etanercept in the treatment of psoriatic arthritis and psoriasis: A randomized trial
    • Mease PJ, Goffe BS, Metz J, et al. Etanercept in the treatment of psoriatic arthritis and psoriasis: A randomized trial. Lancet 2000; 356: 385-90.
    • (2000) Lancet , vol.356 , pp. 385-390
    • Mease, P.J.1    Goffe, B.S.2    Metz, J.3
  • 20
    • 0344926414 scopus 로고    scopus 로고
    • Etanercept as monotherapy in patients with psoriasis
    • Leonardi CL, Powers JL, Matheson RT, et al. Etanercept as monotherapy in patients with psoriasis. N Engl J Med 2003; 349: 2014-22.
    • (2003) N Engl J Med , vol.349 , pp. 2014-2022
    • Leonardi, C.L.1    Powers, J.L.2    Matheson, R.T.3
  • 22
    • 0035068351 scopus 로고    scopus 로고
    • Infliximab for Crohn's disease in clinical practice at the Mayo clinic: The first 100 patients
    • Ricart E, Panaccione R, Loftus EV, et al. Infliximab for Crohn's disease in clinical practice at the Mayo clinic: The first 100 patients. Am J Gastroenterol 2001; 96: 722-9.
    • (2001) Am J Gastroenterol , vol.96 , pp. 722-729
    • Ricart, E.1    Panaccione, R.2    Loftus, E.V.3
  • 23
    • 0033529049 scopus 로고    scopus 로고
    • Infliximab for the treatment of fistula in patients with Crohn's disease
    • Present DH, Rutgeerts P, Targan S, et al. Infliximab for the treatment of fistula in patients with Crohn's disease. N Engl J Med 1999; 340: 1398-405.
    • (1999) N Engl J Med , vol.340 , pp. 1398-1405
    • Present, D.H.1    Rutgeerts, P.2    Targan, S.3
  • 24
    • 0035053968 scopus 로고    scopus 로고
    • An engineered human antibody to TNF (CDP571) for active Crohn's disease: A randomized double-blind placebo-controlled trial
    • Sandbom WJ, Feagan BG, Hanauer SB, et al. An engineered human antibody to TNF (CDP571) for active Crohn's disease: A randomized double-blind placebo-controlled trial. Gastroenterology 2001; 120: 13308.
    • (2001) Gastroenterology , vol.120 , pp. 13308
    • Sandbom, W.J.1    Feagan, B.G.2    Hanauer, S.B.3
  • 25
    • 0034754477 scopus 로고    scopus 로고
    • Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial
    • Sandbom WJ, Hanauer SB, Katz S, et al. Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial. Gastroenterology 2001; 121: 1088-94.
    • (2001) Gastroenterology , vol.121 , pp. 1088-1094
    • Sandbom, W.J.1    Hanauer, S.B.2    Katz, S.3
  • 26
    • 0034775499 scopus 로고    scopus 로고
    • Treatment of intestinal Behçet's syndrome with chimeric tumor necrosis factor α antibody (infliximab)
    • Travis SPL, Czajkowski M, McGovern DPB, et al. Treatment of intestinal Behçet's syndrome with chimeric tumor necrosis factor α antibody (infliximab). Gut 2001; 49: 725-8.
    • (2001) Gut , vol.49 , pp. 725-728
    • Travis, S.P.L.1    Czajkowski, M.2    McGovern, D.P.B.3
  • 27
    • 0035963872 scopus 로고    scopus 로고
    • Effect of infliximab on sight-threatening panuveitis in Behçet's disease
    • Sfikakis PP, Theodossiadis PG, Katsiari CG, et al. Effect of infliximab on sight-threatening panuveitis in Behçet's disease. Lancet 2001; 358: 295-6.
    • (2001) Lancet , vol.358 , pp. 295-296
    • Sfikakis, P.P.1    Theodossiadis, P.G.2    Katsiari, C.G.3
  • 28
    • 0642369396 scopus 로고    scopus 로고
    • The effect of anti-tumor necrosis factor alpha (infliximab) on sight-threatening uveitis in a patient with Behçet's disease
    • Morris DS, Gavin MP, Sturrock RD. The effect of anti-tumor necrosis factor alpha (infliximab) on sight-threatening uveitis in a patient with Behçet's disease. Adv Exp Med Biol 2003; 528: 557-9.
    • (2003) Adv Exp Med Biol , vol.528 , pp. 557-559
    • Morris, D.S.1    Gavin, M.P.2    Sturrock, R.D.3
  • 29
    • 0035033807 scopus 로고    scopus 로고
    • Etanercept combined with conventional treatment in Wegener's granulomatosis: A six-month open-label trial to evaluate safety
    • Stone JH, Uhlfelder ML, Hellmann DB, et al. Etanercept combined with conventional treatment in Wegener's granulomatosis: A six-month open-label trial to evaluate safety. Arthritis Rheum 2001; 44: 1149-54.
    • (2001) Arthritis Rheum , vol.44 , pp. 1149-1154
    • Stone, J.H.1    Uhlfelder, M.L.2    Hellmann, D.B.3
  • 30
    • 0036853090 scopus 로고    scopus 로고
    • Effectiveness of TNF-alpha blockade with infliximab in refractory Wegener's granulomatosis
    • Lamprecht P, Voswinkel J, Lilienthal T, et al. Effectiveness of TNF-alpha blockade with infliximab in refractory Wegener's granulomatosis. Rheumatology 2002; 41: 1303-7.
    • (2002) Rheumatology , vol.41 , pp. 1303-1307
    • Lamprecht, P.1    Voswinkel, J.2    Lilienthal, T.3
  • 31
    • 7044228395 scopus 로고    scopus 로고
    • Induction of remission with infliximab in active generalized Wegener' Granulomatosis is effective but complicated by severe infection
    • Abstract
    • Gause AM, Arbach O, Reinhold-Keller E, et al. Induction of remission with infliximab in active generalized Wegener' Granulomatosis is effective but complicated by severe infection. [Abstract] Arthritis Rheum 2003; 48 (Suppl. 9): S450.
    • (2003) Arthritis Rheum , vol.48 , Issue.SUPPL. 9
    • Gause, A.M.1    Arbach, O.2    Reinhold-Keller, E.3
  • 32
    • 0344628688 scopus 로고    scopus 로고
    • Tumor necrosis factor in sarcoidosis and its potential for targeted therapy
    • Baughman RP, Iannuzzi M. Tumor necrosis factor in sarcoidosis and its potential for targeted therapy. Biodrugs 2003; 17: 425-31.
    • (2003) Biodrugs , vol.17 , pp. 425-431
    • Baughman, R.P.1    Iannuzzi, M.2
  • 33
    • 0041826820 scopus 로고    scopus 로고
    • Potential of tumor necrosis factor neutralization strategies in rheumatologic disorders other than rheumatoid arthritis
    • Stokes DG, Kremer JM. Potential of tumor necrosis factor neutralization strategies in rheumatologic disorders other than rheumatoid arthritis. Sem Arthritis Rheum 2003; 33: 1-18.
    • (2003) Sem Arthritis Rheum , vol.33 , pp. 1-18
    • Stokes, D.G.1    Kremer, J.M.2
  • 34
    • 0029751983 scopus 로고    scopus 로고
    • Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
    • Van Oosten BW, Barkhof F, Truyen L, et al. Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 1996; 47: 1531-4.
    • (1996) Neurology , vol.47 , pp. 1531-1534
    • Van Oosten, B.W.1    Barkhof, F.2    Truyen, L.3
  • 35
    • 0029044028 scopus 로고
    • The therapeutic effects of an enginnered human anti-tumor necrosis factor alpha antibody (CDP571) in rheumatoid arthritis
    • Rankin EC, Choy EGH, Kassimos D, et al. The therapeutic effects of an enginnered human anti-tumor necrosis factor alpha antibody (CDP571) in rheumatoid arthritis. Br J Rheumatol 1995; 34: 334-42.
    • (1995) Br J Rheumatol , vol.34 , pp. 334-342
    • Rankin, E.C.1    Choy, E.G.H.2    Kassimos, D.3
  • 36
    • 0033762622 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with PEGylated recombinant human soluble tumor necrosis factor receptor type I: A clinical update
    • Davis MW, Feige U, Bendele AM, et al. Treatment of rheumatoid arthritis with PEGylated recombinant human soluble tumor necrosis factor receptor type I: A clinical update. Ann Rheum Dis 2000; 59 (Suppl. 1): 141-3.
    • (2000) Ann Rheum Dis , vol.59 , Issue.SUPPL. 1 , pp. 141-143
    • Davis, M.W.1    Feige, U.2    Bendele, A.M.3
  • 37
    • 8044257704 scopus 로고    scopus 로고
    • A metalloproteinase disintegrin that releases TNF-α from cells
    • Black R, Rauch C, Kozlosky C, et al. A metalloproteinase disintegrin that releases TNF-α from cells. Nature 1997; 385: 729-36.
    • (1997) Nature , vol.385 , pp. 729-736
    • Black, R.1    Rauch, C.2    Kozlosky, C.3
  • 38
    • 0027315234 scopus 로고
    • The specific type IV phosphodiesterase inhibitor rolipram suppresses TNF-α production by mononuclear cells
    • Semmler J, Wachtel H, Endres S. The specific type IV phosphodiesterase inhibitor rolipram suppresses TNF-α production by mononuclear cells. Int J Immunopharmacol 1993; 15: 409-13.
    • (1993) Int J Immunopharmacol , vol.15 , pp. 409-413
    • Semmler, J.1    Wachtel, H.2    Endres, S.3
  • 40
    • 18244425295 scopus 로고    scopus 로고
    • The pivotal role of interleukin-1 in the clinical manifestations of rheumatoid arthritis
    • Dayer JM. The pivotal role of interleukin-1 in the clinical manifestations of rheumatoid arthritis. Rheumatology 2003; 42 (Suppl. 2): ii3-10.
    • (2003) Rheumatology , vol.42 , Issue.SUPPL. 2
    • Dayer, J.M.1
  • 41
    • 0037389680 scopus 로고    scopus 로고
    • Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis
    • Fleischmann RM, Schechtman J, Bennett R, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis. Arthritis Rheum 2003; 48: 927-34.
    • (2003) Arthritis Rheum , vol.48 , pp. 927-934
    • Fleischmann, R.M.1    Schechtman, J.2    Bennett, R.3
  • 42
    • 0036190776 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with Anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate. Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
    • Cohen S, Hurd E, Cush J, et al. Treatment of rheumatoid arthritis with Anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate. Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002; 46: 614-24.
    • (2002) Arthritis Rheum , vol.46 , pp. 614-624
    • Cohen, S.1    Hurd, E.2    Cush, J.3
  • 43
    • 0035169507 scopus 로고    scopus 로고
    • Interleukin-15: Biology and Relevance to Human Disease
    • Fehniger T.A, Caligiuri MA. Interleukin-15: Biology and Relevance to Human Disease. Blood 2001; 97: 14-32.
    • (2001) Blood , vol.97 , pp. 14-32
    • Fehniger, T.A.1    Caligiuri, M.A.2
  • 44
    • 0032103993 scopus 로고    scopus 로고
    • Soluble IL-15 Receptor Alpha-Chain Administration Prevents Murine Collagen-Induced Arthritis: A Role for IL-15 in Development of Antigen-Induced Immunopathology
    • Ruchatz H, Leung BP, Wei XQ, et al. Soluble IL-15 Receptor Alpha-Chain Administration Prevents Murine Collagen-Induced Arthritis: A Role for IL-15 in Development of Antigen-Induced Immunopathology. J Immunol 1998; 160: 5654-60.
    • (1998) J Immunol , vol.160 , pp. 5654-5660
    • Ruchatz, H.1    Leung, B.P.2    Wei, X.Q.3
  • 45
    • 0343183719 scopus 로고
    • Targeting the IL-15 Receptor with an Antagonist IL15/Fc Protein Blocks Delayed Type Hypersensitivity
    • Kim Y, Maslinski W, Zheng XX, et al. Targeting the IL-15 Receptor with an Antagonist IL15/Fc Protein Blocks Delayed Type Hypersensitivity. J Immunol 1988; 160: 5742-8.
    • (1988) J Immunol , vol.160 , pp. 5742-5748
    • Kim, Y.1    Maslinski, W.2    Zheng, X.X.3
  • 46
    • 0346096722 scopus 로고    scopus 로고
    • Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model
    • 2203
    • Villadsen LS, Schuurman J, Beurskens F, et al. Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest 2203; 112: 1571-80.
    • J Clin Invest , vol.112 , pp. 1571-1580
    • Villadsen, L.S.1    Schuurman, J.2    Beurskens, F.3
  • 47
    • 0035884819 scopus 로고    scopus 로고
    • An Antagonist IL-15/Fc Protein Prevents Costimulation Blockade-Resistant Rejection
    • Ferrari-Lacraz S, Zheng XX, Kim YS, et al. An Antagonist IL-15/Fc Protein Prevents Costimulation Blockade-Resistant Rejection. J Immunol 2001; 167: 3478-85.
    • (2001) J Immunol , vol.167 , pp. 3478-3485
    • Ferrari-Lacraz, S.1    Zheng, X.X.2    Kim, Y.S.3
  • 48
    • 1542303614 scopus 로고    scopus 로고
    • A novel human monoclonal antibody against IL-15 (HuMax-IL-15) in patients with active Rheumatoid arthritis: Results of a double-blind placebo-controlled phase I/II trial
    • Abstract
    • Baslund B, Tvede N, Danneskiold-Samsoe B, et al. A novel human monoclonal antibody against IL-15 (HuMax-IL-15) in patients with active Rheumatoid arthritis: Results of a double-blind placebo-controlled phase I/II trial. [Abstract] Arthritis Rheum 2003; 48 (Suppl. 9): S1706.
    • (2003) Arthritis Rheum , vol.48 , Issue.SUPPL. 9
    • Baslund, B.1    Tvede, N.2    Danneskiold-Samsoe, B.3
  • 49
    • 0037231538 scopus 로고    scopus 로고
    • Setting the cytokine trap for autoimmunity
    • Dinarello CA. Setting the cytokine trap for autoimmunity. Nature Med 2003; 9: 20-2.
    • (2003) Nature Med , vol.9 , pp. 20-22
    • Dinarello, C.A.1
  • 50
    • 0037231664 scopus 로고    scopus 로고
    • Cytokine traps: Multi-component, high-affinity blockers of cytokine action
    • Economides AN, Carpenter LR, Rudge JS, et al. Cytokine traps: Multi-component, high-affinity blockers of cytokine action. Nature Med 2003; 9: 47-52.
    • (2003) Nature Med , vol.9 , pp. 47-52
    • Economides, A.N.1    Carpenter, L.R.2    Rudge, J.S.3
  • 51
    • 17844403234 scopus 로고    scopus 로고
    • Results of a phase I/II randomized, masked, placebo-controlled trial of recombinant human interleukin-II (rhIL-11) in the treatment of subjects with active rheumatoid arthritis
    • Moreland L, Gugliotti R, King K, et al. Results of a phase I/II randomized, masked, placebo-controlled trial of recombinant human interleukin-II (rhIL-11) in the treatment of subjects with active rheumatoid arthritis. Arthritis Res 2001; 3: 247-52.
    • (2001) Arthritis Res , vol.3 , pp. 247-252
    • Moreland, L.1    Gugliotti, R.2    King, K.3
  • 52
    • 0345251966 scopus 로고    scopus 로고
    • Interleukin 10 treatment of psoriasis: Clinical results of a Phase II trial
    • Asadullah K, Docke WD, Ebeling M, et al. Interleukin 10 treatment of psoriasis: Clinical results of a Phase II trial. Arch Dermatol 1999; 135: 187-92.
    • (1999) Arch Dermatol , vol.135 , pp. 187-192
    • Asadullah, K.1    Docke, W.D.2    Ebeling, M.3
  • 53
    • 0027521002 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis
    • Paty DW, Li DK. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. Neurology 1993; 43: 662-7.
    • (1993) Neurology , vol.43 , pp. 662-667
    • Paty, D.W.1    Li, D.K.2
  • 54
    • 0035849494 scopus 로고    scopus 로고
    • Randomised controlled trial of interferon-beta-1a in secondary progressive MS: MR1 results
    • Li DK, Zhao GJ, Paty DW. Randomised controlled trial of interferon-beta-1a in secondary progressive MS: MR1 results. Neurology 2001; 56: 1505-13.
    • (2001) Neurology , vol.56 , pp. 1505-1513
    • Li, D.K.1    Zhao, G.J.2    Paty, D.W.3
  • 55
    • 0035163042 scopus 로고    scopus 로고
    • Phase I clinical trial of a monoclonal antibody against CD40-ligand (IDEC-131) in patients with systemic lupus erythematosus
    • Davis JC, Jr, Totoritis MC, Rosenberg J, et al. Phase I clinical trial of a monoclonal antibody against CD40-ligand (IDEC-131) in patients with systemic lupus erythematosus. J Rheumatol 2001; 28: 95-101.
    • (2001) J Rheumatol , vol.28 , pp. 95-101
    • Davis Jr., J.C.1    Totoritis, M.C.2    Rosenberg, J.3
  • 56
    • 0345824714 scopus 로고    scopus 로고
    • Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions
    • Grammer AC, Slota R, Fischer R, et al. Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. J Clin Invest 2003; 112: 1506-20.
    • (2003) J Clin Invest , vol.112 , pp. 1506-1520
    • Grammer, A.C.1    Slota, R.2    Fischer, R.3
  • 57
    • 1542363438 scopus 로고    scopus 로고
    • CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
    • Abrams JR, Lebwohl MG, Guzzo CA, et al. CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris. J Clin Invest 1999; 303: 3243-52.
    • (1999) J Clin Invest , vol.303 , pp. 3243-3252
    • Abrams, J.R.1    Lebwohl, M.G.2    Guzzo, C.A.3
  • 58
    • 0242574700 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis by selective inhibition of T. cell activation with fusion protein CTLA4Ig
    • Kremer JM, Westhovens R, Leon M, et al. Treatment of rheumatoid arthritis by selective inhibition of T. cell activation with fusion protein CTLA4Ig. N Engl J Med 2003; 349: 1907-15.
    • (2003) N Engl J Med , vol.349 , pp. 1907-1915
    • Kremer, J.M.1    Westhovens, R.2    Leon, M.3
  • 59
    • 0038824717 scopus 로고    scopus 로고
    • Alefacept therapy produces remission for patients with chronic plaque psoriasis
    • Krueger GG, Ellis CN. Alefacept therapy produces remission for patients with chronic plaque psoriasis. Br J Dermatol 2003; 148: 784-8.
    • (2003) Br J Dermatol , vol.148 , pp. 784-788
    • Krueger, G.G.1    Ellis, C.N.2
  • 60
    • 0345107256 scopus 로고    scopus 로고
    • A novel targeted T-cell modulator, efalizumab, for plaque psoriasis
    • Lebwohl M. Tyring SK, Hamilton TK, et al. A novel targeted T-cell modulator, efalizumab, for plaque psoriasis. N Engl J Med 2003; 349: 2004-13.
    • (2003) N Engl J Med , vol.349 , pp. 2004-2013
    • Lebwohl, M.1    Tyring, S.K.2    Hamilton, T.K.3
  • 61
    • 0042530461 scopus 로고    scopus 로고
    • The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airwayresponses and airway inflammation in subjects with atopic asthma
    • Gauvreau GM, Becker AB, Boulet LP, et al at. The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airwayresponses and airway inflammation in subjects with atopic asthma. J Allergy Clin Immunol 2003; 112: 331-8.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 331-338
    • Gauvreau, G.M.1    Becker, A.B.2    Boulet, L.P.3
  • 62
    • 0037413468 scopus 로고    scopus 로고
    • Natalizumab for active Crohn's disease
    • Ghosh S, Goldin E, Gordon FH, et al. Natalizumab for active Crohn's disease. N Engl J Med 2003; 348: 24-32.
    • (2003) N Engl J Med , vol.348 , pp. 24-32
    • Ghosh, S.1    Goldin, E.2    Gordon, F.H.3
  • 63
    • 0037413467 scopus 로고    scopus 로고
    • A controlled trial of Natalizumab for relapsing multiple sclerosis
    • Miller DH, Khan OA, Sheremata WA, et al. A controlled trial of Natalizumab for relapsing multiple sclerosis. N Engl J Med 2003; 348: 15-23.
    • (2003) N Engl J Med , vol.348 , pp. 15-23
    • Miller, D.H.1    Khan, O.A.2    Sheremata, W.A.3
  • 64
    • 0037638841 scopus 로고    scopus 로고
    • Rituximab therapy and autoimmune disorders. Prospects for antoimmune cell therapy
    • Silverman GJ, Weisman S. Rituximab therapy and autoimmune disorders. Prospects for antoimmune cell therapy. Arthritis Rheum 2003; 48: 1484-92.
    • (2003) Arthritis Rheum , vol.48 , pp. 1484-1492
    • Silverman, G.J.1    Weisman, S.2
  • 65
    • 0142181040 scopus 로고    scopus 로고
    • Autoimmune aspects of cytokine and anticytokine therapies
    • Krause I, Valesini G, Scrivo R, Shoenfeld Y. Autoimmune aspects of cytokine and anticytokine therapies. Am J Med 2003; 115: 390-7.
    • (2003) Am J Med , vol.115 , pp. 390-397
    • Krause, I.1    Valesini, G.2    Scrivo, R.3    Shoenfeld, Y.4
  • 66
    • 0142103968 scopus 로고    scopus 로고
    • Monitoring by rheumatologists for methotrexate-, etanercept-, infliximab-, and anakinra-associated adverse events
    • Yazici Y, Erkan D, Paget SA. Monitoring by rheumatologists for methotrexate-, etanercept-, infliximab-, and anakinra-associated adverse events. Arthritis Rheum 2003; 48: 2769-72.
    • (2003) Arthritis Rheum , vol.48 , pp. 2769-2772
    • Yazici, Y.1    Erkan, D.2    Paget, S.A.3
  • 67
    • 0031884806 scopus 로고    scopus 로고
    • Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis
    • McInnes IB, Liew FY. Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis. Immunol Today 1998; 19: 75-9.
    • (1998) Immunol Today , vol.19 , pp. 75-79
    • McInnes, I.B.1    Liew, F.Y.2
  • 68
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflammation in rheumatoid arthritis
    • Choy EHS, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001; 344: 907-16.
    • (2001) N Engl J Med , vol.344 , pp. 907-916
    • Choy, E.H.S.1    Panayi, G.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.