Genetic Variation Versus Recombination Rate in a Structured Population of Mice

Molecular Biology and Evolution

Volumn 21, Issue 2, 2004, Pages 404-409

  Takahashi, Aya ^a   Liu, Yu Hua ^a,b   Saitou, Naruya ^a  

^a NATIONAL INSTITUTE OF GENETICS   (Japan)

^b JACKSON LABORATORY   (United States)

Author keywords

Background selection; FST; Genetic hitchhiking; Mus musculus; Population structure; Population subdivision; Recombination rate

Indexed keywords

DNA; NUCLEOTIDE;

ARTICLE; GENE; GENE MAPPING; GENETIC RECOMBINATION; GENETIC VARIABILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; UNINDEXED SEQUENCE;

ANIMALS; CHROMOSOME MAPPING; GENETICS, POPULATION; LINKAGE (GENETICS); MICE; QUANTITATIVE TRAIT LOCI; RECOMBINATION, GENETIC; SPECIES SPECIFICITY; VARIATION (GENETICS);

MAMMALIA; MUS; MUS MUSCULUS; MUS SPICILEGUS; MUSCULUS;

EID: 1542316900     PISSN: 07374038     EISSN: None     Source Type: Journal    
DOI: 10.1093/molbev/msh030     Document Type: Article

References (38)

1. Andolfatto, P., and M. Przeworski. 2001. Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster. Genetics 158:657-665.
2. Aquadro, C. F., D. J. Begun, and E. C. Kindahl. 1994. Selection, recombination, and DNA polymorphism in Drosophila. Pp. 46-56 in B. Golding, ed. Non-neutral evolution: theories and molecular data. Chapman and Hall, New York.
3. Begun, D. J., and C. F. Aquadro. 1992. Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster. Nature 356:519-520.
4. -. 1993. African and North American populations of Drosophila melanogaster are very different at the DNA level. Nature 365:548-550.
5. Betancourt, A. J., and D. C. Presgraves. 2002. Linkage limits the power of natural selection in Drosophila. Proc. Natl. Acad. Sci. USA 99:13616-13620.
6. Bonhomme, F., and J.-L. Guenet. 1989. The wild house mouse and its relatives. Pp. 649-662 in M. F. Lyon and A. G. Searle, eds. Genetic variants and strains of the laboratory mouse. Gustav Fischer Verlag, Stuttgart Germany.
7. Charlesworth, B., M. T. Morgan, and D. Charlesworth. 1993. The effect of deleterious mutations on neutral molecular variation. Genetics 134:1289-1303.
8. Charlesworth, B., M. Nordborg, and D. Charlesworth. 1997. The effects of local selection, balanced polymorphism and background selection on equilibrium patterns of genetic diversity in subdivided populations. Genet. Res. 70:155-174.
9. Charlesworth, D., B. Charlesworth, and M. T. Morgan. 1995. The pattern of neutral molecular variation under the background selection model. Genetics 141:1619-1632.
10. Fay, J., and C.-I. Wu. 2000. Hitchhiking under positive Darwinian selection. Genetics 155:1405-1413.
11. Fu, Y.-X., and W.-H. Li. 1993. Statistical tests of neutrality of mutations. Genetics 133:693-709.
12. Hellman, I., I. Erbersberger, S. E. Ptak, S. Paabo, and M. Przeworski. 2003. A neutral explanation for the correlation of diversity with recombination rates in humans. Am. J. Hum. Genet. 72:1527-1535.
13. Hudson, R. R., and N. L. Kaplan. 1995. The coalescent process and background selection. Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci. 349:19-23.
14. Kaplan, N. L., R. R. Hudson, and C. H. Langley. 1989. The "hitchhiking effect" revisited. Genetics 123:887-899.
15. Koide, T., K. Moriwaki, K. Ikeda, H. Niki, and T. Shiroishi. 2000. Multi-phenotype behavioral characterization of inbred strains derived from wild stocks of Mus musculus. Mamm. Genome 11:664-670.
16. a) regions of the Drosophila melanogaster X chromosome. Genetics 156:1837-1852.
17. Lercher, M. J., and L. D. Hurst. 2002. Human SNP variability and mutation rate are higher in regions of high recombination. Trends Genet. 18:337-340.
18. Maynard Smith, J., and J. Haigh. 1974. The hitch-hiking effect of a favorable gene. Genet. Res. 23:23-35.
19. Moriwaki, K., T. Shiroishi, and H. Yonekawa. 1994. Genetics in wild mice. Japan Sci. Soc Press, Tokyo/S Karger, Basel.
20. Nachman, M. W. 1997. Patterns of DNA variability at X-linked loci in Mus domesticus. Genetics 147:1303-1316.
21. -. 2001. Single nucleotide polymorphisms and recombination rate in humans. Trends Genet. 17:481-485.
22. Nachman, M. W., V. L. Bauer, S. L. Crowell, and C. F. Aquadro. 1998. DNA variability and recombination rates at X-linked loci in humans. Genetics 150:1133-1141.
23. Nachman, M. W., and G. A. Churchill. 1996. Heterogeneity in rates of recombination across the mouse genome. Genetics 142:537-548.
24. Nei, M. 1973. Analysis of gene diversity in subdivided populations. Proc. Natl. Acad. Sci. USA 70:3321-3323.
25. -. 1987. Molecular evolutionary genetics. Columbia University Press, New York.
26. Payseur, B. A., and M. W. Nachman. 2000. Microsatellite variation and recombination rate in the human genome. Genetics 156:1285-1298.
27. Przeworski, M. 2002. The signature of positive selection at randomly chosen loci. Genetics 160:1179-1189.
28. Przeworski, M., R. R. Hudson, and A. Di Rienzo. 2000. Adjusting the focus on human variation. Trends Genet. 16:296-302.
29. Sage, R. D., W. R. Atchley, and C. Ernesto. 1993. House mice as models in systematic biology. Syst. Biol. 42:523-561.
30. She, J. X., F. Bonhomme, P. Boursot, L. Thaler, and F. Catzeflis. 1990. Molecular phylogenies in the genus Mus: Comparative analysis of electrophoretic, scnDNA hybridization, and mtDNA RFLP data. Biol. J. Linn. Soc. 41:83-103.
31. Slatkin, M., and T. Wiehe. 1998. Genetic hitch-hiking in a subdivided population. Genet. Res. 71:155-160.
32. Stephan, W. 1994. Effects of genetic recombination and population subdivision on nucleotide sequence variation in Drosophila ananassae. Pp. 57-66 in B. Golding, ed. Non-neutral evolution: theories and molecular data. Chapman and Hall, New York.
33. Stephan, W., and S. J. Mitchell. 1992. Reduced levels of DNA polymorphism and fixed between-population differences in the centromeric region of Drosophila ananassae. Genetics 132:1039-1045.
34. Stephan, W., L. Xing, D. A. Kirby, and J. M. Braverman. 1998. A test of the background selection hypothesis based on nucleotide data from Drosophila ananassae. Proc. Natl. Acad. Sci. USA 95:5649-5654.
35. Tajima, F. 1989. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123:585-595.
36. Van Etten, W. J., R. G. Steen, H. Nguyen, A. B. Castle, D. K. Slonim, B. Ge, C. Nusbaum, G. D. Schuler, E. S. Lander, and T. J. Hudson. 1999. Radiation hybrid map of the mouse genome. Nat. Genet. 22:384-387.
37. Wall, J. D. 1999. Recombination and the power of statistical tests of neutrality. Genet. Res. 74:65-79.
38. Yonekawa, H., K. Moriwaki, O. Gotoh, N. Miyashita, Y. Matsushima, L. M. Shi, W. S. Cho, X. L. Zhen, and Y. Tagashira. 1988. Hybrid origin of Japanese mice "Mus musculus molossinus": evidence from restriction analysis of mitochondrial DNA. Mol. Biol. Evol. 5:63-78.