메뉴 건너뛰기




Volumn 75, Issue 3, 2004, Pages 163-171

Activities of cytochrome P450 1A2, N-acetyltransferase 2, xanthine oxidase, and cytochrome P450 2D6 are unaltered in children with cystic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; BIOLOGICAL MARKER; CAFFEINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2D6; DEXTROMETHORPHAN; ISOENZYME; LIVER ENZYME; XANTHINE OXIDASE;

EID: 1542316308     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clpt.2003.10.005     Document Type: Article
Times cited : (16)

References (52)
  • 1
    • 0027395872 scopus 로고
    • The changing epidemiology of cystic fibrosis
    • FitzSimmons S.C. The changing epidemiology of cystic fibrosis. J Pediatr. 122:1993;1-9.
    • (1993) J Pediatr , vol.122 , pp. 1-9
    • Fitzsimmons, S.C.1
  • 2
    • 0034776733 scopus 로고    scopus 로고
    • Perspectives on gene therapy for cystic fibrosis airway disease
    • Bigger B., Coutelle C. Perspectives on gene therapy for cystic fibrosis airway disease. BioDrugs. 15:2001;615-634.
    • (2001) BioDrugs , vol.15 , pp. 615-634
    • Bigger, B.1    Coutelle, C.2
  • 4
    • 0025763746 scopus 로고
    • Ibuprofen in children with cystic fibrosis: Pharmacokinetics and adverse effects
    • Konstan M.W., Hoppel C.L., Chai B., Davis P.B. Ibuprofen in children with cystic fibrosis pharmacokinetics and adverse effects. J Pediatr. 118:1991;956-964.
    • (1991) J Pediatr , vol.118 , pp. 956-964
    • Konstan, M.W.1    Hoppel, C.L.2    Chai, B.3    Davis, P.B.4
  • 6
    • 0025688396 scopus 로고
    • Altered pharmacokinetics of cyclosporine in heart-lung transplant recipients with cystic fibrosis
    • Tan K.K.C., Hue K.L., Strickland S.E., Trull A.K., Smyth R.L., Scott J.P., et al. Altered pharmacokinetics of cyclosporine in heart-lung transplant recipients with cystic fibrosis. Ther Drug Monit. 12:1990;520-524.
    • (1990) Ther Drug Monit , vol.12 , pp. 520-524
    • Tan, K.K.C.1    Hue, K.L.2    Strickland, S.E.3    Trull, A.K.4    Smyth, R.L.5    Scott, J.P.6
  • 7
    • 0021253893 scopus 로고
    • Disposition of tobramycin in patients with cystic fibrosis: A prospective controlled study
    • Levy J, Smith AL, Koup JR, Williams-Warren J, Ramsey B. Disposition of tobramycin in patients with cystic fibrosis: a prospective controlled study. J Pediatr 1984;105:117-24
    • (1984) J Pediatr , vol.105 , pp. 117-124
    • Levy, J.1    Smith, A.L.2    Koup, J.R.3    Williams-Warren, J.4    Ramsey, B.5
  • 8
    • 0019915904 scopus 로고
    • The nephropathy of cystic fibrosis: A human model of chronic nephrotoxicity
    • Abramowsky C.R., Swinehart G.L. The nephropathy of cystic fibrosis a human model of chronic nephrotoxicity. Hum Pathol. 13:1982;934-939.
    • (1982) Hum Pathol , vol.13 , pp. 934-939
    • Abramowsky, C.R.1    Swinehart, G.L.2
  • 11
    • 0015580731 scopus 로고
    • The effect of age on alkaline phosphatase and other serologic liver function tests in normal subjects and patients with cystic fibrosis
    • Kattwinkl J., Taussig L.M., Statland B.E., Vertes J.E. The effect of age on alkaline phosphatase and other serologic liver function tests in normal subjects and patients with cystic fibrosis. J Pediatr. 82:1973;234-242.
    • (1973) J Pediatr , vol.82 , pp. 234-242
    • Kattwinkl, J.1    Taussig, L.M.2    Statland, B.E.3    Vertes, J.E.4
  • 17
    • 1542324612 scopus 로고
    • Theophylline (THEO) biotransformation in normal and diseased human livers
    • [abstract]
    • Dranitsaris G., Spino M., Tesoro A., Phillips M.J., Cox K. Theophylline (THEO) biotransformation in normal and diseased human livers. [abstract] Clin Pharmacol Ther. 51:1992;162.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 162
    • Dranitsaris, G.1    Spino, M.2    Tesoro, A.3    Phillips, M.J.4    Cox, K.5
  • 18
    • 0028357395 scopus 로고
    • Disposition of drugs in cystic fibrosis. VII. Acetylation of sulfamethoxazole in blood cells: In vitro-in vivo correlation and characterization of its kinetics of acetylation in lymphocytes
    • Hutabarat R.M., Smith A.L., Unadkat J.D. Disposition of drugs in cystic fibrosis. VII. Acetylation of sulfamethoxazole in blood cells in vitro-in vivo correlation and characterization of its kinetics of acetylation in lymphocytes. Clin Pharmacol Ther. 55:1994;427-433.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 427-433
    • Hutabarat, R.M.1    Smith, A.L.2    Unadkat, J.D.3
  • 19
    • 0027437502 scopus 로고
    • Disposition of drugs in cystic fibrosis. V. in vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosis
    • O'Sullivan T.A., Wang J.P., Unadkat J.D., Al-Habet S.M.H., Trager W.F., Smith A.L., et al. Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosis. Clin Pharmacol Ther. 54:1993;323-338.
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 323-338
    • O'Sullivan, T.A.1    Wang, J.P.2    Unadkat, J.D.3    Al-Habet, S.M.H.4    Trager, W.F.5    Smith, A.L.6
  • 20
    • 0028352381 scopus 로고
    • Disposition of drugs in cystic fibrosis. VI. in vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including CYP3A4) is not enhanced in cystic fibrosis
    • Wang J.P., Unadakat J.D., McNamara S., O'Sullivan T.A., Smith A.L., Trager W.F., et al. Disposition of drugs in cystic fibrosis. VI. In vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including CYP3A4) is not enhanced in cystic fibrosis. Clin Pharmacol Ther. 55:1994;528-534.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 528-534
    • Wang, J.P.1    Unadakat, J.D.2    McNamara, S.3    O'Sullivan, T.A.4    Smith, A.L.5    Trager, W.F.6
  • 22
    • 0029763158 scopus 로고    scopus 로고
    • CYP2D5, N-acetylation and xanthine oxidase activity in cystic fibrosis
    • Bosso J.A., Liu Q., Evans W.E., Relling M.V. CYP2D5, N-acetylation and xanthine oxidase activity in cystic fibrosis. Pharmacotherapy. 16:1996;749-753.
    • (1996) Pharmacotherapy , vol.16 , pp. 749-753
    • Bosso, J.A.1    Liu, Q.2    Evans, W.E.3    Relling, M.V.4
  • 26
    • 0024379208 scopus 로고
    • Dextromethorphan and caffeine as probes for simultaneous determination of debrisoquin-oxidation and N-acetylation phenotypes in children
    • Evans W.E., Relling M.V., Petros W.P., Meyer W.H., Mirro J., Crom W.R. Dextromethorphan and caffeine as probes for simultaneous determination of debrisoquin-oxidation and N-acetylation phenotypes in children. Clin Pharmacol Ther. 45:1989;568-573.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 568-573
    • Evans, W.E.1    Relling, M.V.2    Petros, W.P.3    Meyer, W.H.4    Mirro, J.5    Crom, W.R.6
  • 27
    • 0031975185 scopus 로고    scopus 로고
    • Update: Clinically significant cytochrome P450 drug interactions
    • Michalets E.L. Update clinically significant cytochrome P450 drug interactions. Pharmacotherapy. 18:1998;84-112.
    • (1998) Pharmacotherapy , vol.18 , pp. 84-112
    • Michalets, E.L.1
  • 28
    • 0033461165 scopus 로고    scopus 로고
    • Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data
    • Gaedigk A., Gotschall R.R., Forbes N.S., Simon S.D., Kearns G.L., Leeder J.S. Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data. Pharmacogenetics. 9:1999;669-682.
    • (1999) Pharmacogenetics , vol.9 , pp. 669-682
    • Gaedigk, A.1    Gotschall, R.R.2    Forbes, N.S.3    Simon, S.D.4    Kearns, G.L.5    Leeder, J.S.6
  • 29
    • 0036339071 scopus 로고    scopus 로고
    • Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans
    • Gaedigk A., Bradford L.D., Marcucci K.A., Leeder J.S. Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans. Clin Pharmacol Ther. 72:2002;76-89.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 76-89
    • Gaedigk, A.1    Bradford, L.D.2    Marcucci, K.A.3    Leeder, J.S.4
  • 30
    • 0021151820 scopus 로고
    • A simple test for acetylator phenotyping using caffeine
    • Grant D., Tang B., Kalow W. A simple test for acetylator phenotyping using caffeine. Br J Clin Pharmacol. 17:1984;459-464.
    • (1984) Br J Clin Pharmacol , vol.17 , pp. 459-464
    • Grant, D.1    Tang, B.2    Kalow, W.3
  • 32
    • 0031863228 scopus 로고    scopus 로고
    • Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2 and xanthine oxidase activity determined with caffeine phenotyping
    • Kashuba A.D.M., Bertino J.S., Kearns G.L., Leeder J.S.L., James A.W., Gotschall R.R., et al. Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2 and xanthine oxidase activity determined with caffeine phenotyping. Clin Pharmacol Ther. 63:1998;540-551.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 540-551
    • Kashuba, A.D.M.1    Bertino, J.S.2    Kearns, G.L.3    Leeder, J.S.L.4    James, A.W.5    Gotschall, R.R.6
  • 33
    • 0023227456 scopus 로고
    • A urinary caffeine metabolite ratio that reflects systemic caffeine clearance
    • Campbell M.E., Spielberg S.P., Kalow W. A urinary caffeine metabolite ratio that reflects systemic caffeine clearance. Clin Pharmacol Ther. 42:1987;157-165.
    • (1987) Clin Pharmacol Ther , vol.42 , pp. 157-165
    • Campbell, M.E.1    Spielberg, S.P.2    Kalow, W.3
  • 35
    • 0025892853 scopus 로고
    • Caffeine as a metabolic probe: Validation of its use for acetylator phenotyping
    • Tang B.K., Kadar D., Qian L., Iriah J., Yip J., Kalow W. Caffeine as a metabolic probe validation of its use for acetylator phenotyping. Clin Pharmacol Ther. 49:1991;648-657.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 648-657
    • Tang, B.K.1    Kadar, D.2    Qian, L.3    Iriah, J.4    Yip, J.5    Kalow, W.6
  • 36
    • 0022338958 scopus 로고
    • Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation
    • Schmid B., Bircher J., Preisig R., Kupfer A. Polymorphic dextromethorphan metabolism co-segregation of oxidative O-demethylation with debrisoquin hydroxylation. Clin Pharmacol Ther. 38:1985;618-624.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 618-624
    • Schmid, B.1    Bircher, J.2    Preisig, R.3    Kupfer, A.4
  • 39
    • 0017229258 scopus 로고
    • The effect of arterial oxygen tension on antipyrine half-life in plasma
    • Cumming J.F. The effect of arterial oxygen tension on antipyrine half-life in plasma. Clin Pharmacol Ther. 19:1976;468-471.
    • (1976) Clin Pharmacol Ther , vol.19 , pp. 468-471
    • Cumming, J.F.1
  • 40
    • 0017808146 scopus 로고
    • Chronic pulmonary disease and antipyrine disposition
    • Agnihotri S., Clark R., Cooper S. Chronic pulmonary disease and antipyrine disposition. Br J Clin Pharmacol. 5:1978;275-277.
    • (1978) Br J Clin Pharmacol , vol.5 , pp. 275-277
    • Agnihotri, S.1    Clark, R.2    Cooper, S.3
  • 41
    • 0029809657 scopus 로고    scopus 로고
    • Drug metabolism in liver disease: Implications for therapeutic monitoring
    • Sonne J. Drug metabolism in liver disease implications for therapeutic monitoring. Ther Drug Monit. 18:1996;397-401.
    • (1996) Ther Drug Monit , vol.18 , pp. 397-401
    • Sonne, J.1
  • 42
    • 0025649763 scopus 로고
    • Enhanced hepatic drug clearance in patients with cystic fibrosis
    • Kearns G.L., Mallory G.B., Crom W.R., Evans W.E. Enhanced hepatic drug clearance in patients with cystic fibrosis. J Pediatr. 117:1990;972-979.
    • (1990) J Pediatr , vol.117 , pp. 972-979
    • Kearns, G.L.1    Mallory, G.B.2    Crom, W.R.3    Evans, W.E.4
  • 44
    • 0027197152 scopus 로고
    • The use of caffeine for enzyme assays: A critical appraisal
    • Kalow W., Tang B.K. The use of caffeine for enzyme assays a critical appraisal. Clin Pharmacol Ther. 53:1993;503-514.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 503-514
    • Kalow, W.1    Tang, B.K.2
  • 45
    • 0021288082 scopus 로고
    • Role of cytochrome P450 and related enzymes in the pulmonary metabolism of xenobiotics
    • Philpot R.M., Smith B.R. Role of cytochrome P450 and related enzymes in the pulmonary metabolism of xenobiotics. Environ Health Perspect. 55:1981;359-367.
    • (1981) Environ Health Perspect , vol.55 , pp. 359-367
    • Philpot, R.M.1    Smith, B.R.2
  • 46
  • 48
    • 0344840980 scopus 로고    scopus 로고
    • Evaluation of caffeine as a test drug for CYP1A2, NAT-2 and CYP2E1 phenotyping in man by in-vivo versus in-vitro correlations
    • Fuhr U., Rost K.L., Englehardt R., Sachs M., Liermann D., Belloc C., et al. Evaluation of caffeine as a test drug for CYP1A2, NAT-2 and CYP2E1 phenotyping in man by in-vivo versus in-vitro correlations. Pharmacogenetics. 6:1996;159-176.
    • (1996) Pharmacogenetics , vol.6 , pp. 159-176
    • Fuhr, U.1    Rost, K.L.2    Englehardt, R.3    Sachs, M.4    Liermann, D.5    Belloc, C.6
  • 49
    • 0035036756 scopus 로고    scopus 로고
    • Multidrug resistance p-glycoprotein 2 is essential for the biliary excretion of indocyanine green
    • Huang L., Vore M. Multidrug resistance p-glycoprotein 2 is essential for the biliary excretion of indocyanine green. Drug Metab Dispos. 29:2001;634-637.
    • (2001) Drug Metab Dispos , vol.29 , pp. 634-637
    • Huang, L.1    Vore, M.2
  • 50
    • 0030892062 scopus 로고    scopus 로고
    • Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice
    • Trezise A.E.O., Ratcliff R., Hawkins T.E., Evans M.J., Freeman T.C., Romano P.R., et al. Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice. Hum Mol Genet. 6:1997;527-537.
    • (1997) Hum Mol Genet , vol.6 , pp. 527-537
    • Trezise, A.E.O.1    Ratcliff, R.2    Hawkins, T.E.3    Evans, M.J.4    Freeman, T.C.5    Romano, P.R.6
  • 51
    • 0026451638 scopus 로고
    • The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression
    • Trezie A.E.O., Romano P.R., Gill D.R., Hyde S.C., Sepulveda F.V., Buchwald M., et al. The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression. EMBO J. 11:1992;4291-4303.
    • (1992) EMBO J , vol.11 , pp. 4291-4303
    • Trezie, A.E.O.1    Romano, P.R.2    Gill, D.R.3    Hyde, S.C.4    Sepulveda, F.V.5    Buchwald, M.6
  • 52
    • 33947107549 scopus 로고    scopus 로고
    • Disposition of acetaminophen and indocyanine green in cystic fibrosis knockout mice
    • Kulkarni S.G., Pegram A.A., Smith P.C. Disposition of acetaminophen and indocyanine green in cystic fibrosis knockout mice. AAPS PharmSci. 2:2002;E18.
    • (2002) AAPS PharmSci , vol.2 , pp. 18
    • Kulkarni, S.G.1    Pegram, A.A.2    Smith, P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.