An assay of microsomal membrane-associated proteasomes demonstrates increased proteolytic activity in skeletal muscle of intensive care unit patients

Clinical Nutrition

Volumn 24, Issue 2, 2005, Pages 259-265

  Klaude, Maria ^a   Hammarqvist, Folke ^a   Wemerman, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Critical illness; Muscle wasting; Proteasome activity

Indexed keywords

COUMARIN DERIVATIVE; MESSENGER RNA; MUSCLE PROTEIN; POLYUBIQUITIN; PROTEASOME;

ADULT; AGED; ARTICLE; CATABOLISM; CATALYSIS; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRITICAL ILLNESS; CYTOSOL; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME SUBUNIT; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INTENSIVE CARE UNIT; LEG MUSCLE; MALE; MICROSOME MEMBRANE; MOLECULAR RECOGNITION; MUSCLE ATROPHY; MUSCLE BIOPSY; PROTEIN DEGRADATION; SKELETAL MUSCLE; SOLUBILITY; ULTRACENTRIFUGATION;

AGED; AGED, 80 AND OVER; BIOLOGICAL ASSAY; BIOPSY; CASE-CONTROL STUDIES; CRITICAL ILLNESS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTENSIVE CARE UNITS; MALE; MICROSOMES; MIDDLE AGED; MUSCLE, SKELETAL; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITINS;

EID: 15344350012     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2004.11.002     Document Type: Article

References (35)

1. L. Gamrin K. Andersson E. Hultman E. Nilsson P. Essén J. Wernerman Longitudinal changes of biochemical parameters in muscle during critical illness Metabolism 46 1997 756-762
2. D.W. Wilmore R.J. Smith S.T. O'Dwyer D.O. Jacobs T.R. Ziegler X.D. Wang The gut A central organ after surgical stress Surgery 104 1988 917-923
3. P.O. Hasselgren R. Jagenburg L. Karlstrom P. Pedersen T. Seeman Changes of protein metabolism in liver and skeletal muscle following trauma complicated by sepsis J Trauma 24 1984 224-227
4. A. Ciechanover A. Orian A.L. Schwartz Ubiquitin-mediated proteolysis: Biological regulation via destruction BioEssays 22 2000 442-451
5. W. Baumeister J. Walz F. Zühl E. Seemüller The proteasome: Paradigm of a self-compartmentalizing protease Cell 92 1998 367-380
6. K.L. Rock C. Gram L. Rothstein et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules Cell 78 1992 761-771
7. A.F. Kisselev T.N. Akopian V. Castillo A.L. Goldberg Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown Mol Cell 4 1999 395-402
8. M. Rechsteiner C. Realini V. Ustrell The proteasome activator 11S REG (PA28) and class I antigen presentation Biochem J 345 2000 1-15
9. P. Brooks G. Fuertes R.Z. Murray et al. Subcellular localization of proteasomes and their complexes in mammalian cells Biochem J 346 2000 155-161
10. 2+-activated, and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients Proc Natl Acad Sci USA 93 1996 2714-2718
11. A. Von der Decken F. Hammarqvist E. Vinnars J. Wernerman Degradation of proteins in human skeletal muscle: Characterisation of the biopsy system and its application to patients undergoing abdominal surgery J Clin Biochem Nutr 14 1993 121-132
12. R. Medina S.S. Wing A.L. Goldberg Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy Biochem J 307 1995 631-637
13. S.R. Price J.L. Bailey X. Wang et al. Muscle wasting in insulinopenic rats results from activation of the ATP dependent ubiquitin-proteasome pathway by a mechanism including gene transcription J Clin Invest 98 1996 1703-1708
14. S.C. Hobler A. Williams D. Fischer Activity and expression of the 20S proteasome are increased in skeletal muscle during sepsis Am J Physiol 46 1999 R434-R440
15. D. Auclair D.R. Garrel A. Chaouki Zerouala L.H. Ferland Activation of the ubiquitin pathway in rat skeletal muscle by catabolic doses of glucocorticoids Am J Physiol 272 1997 C1007-C1016
16. G. Biolo A. Bosutti F. Iscra G. Toigo A. Gullo G. Guarnieri Contribution of the ubiquitin-proteasome pathway to overall muscle proteolysis in hypercatabolic patients Metabolism 49 6 2000 689-691
17. A. Williams X. Sun J.E. Fischer P.O. Hasselgren The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with cancer Surgery 126 1999 744-749
18. G. Tiao S. Hobler J.J. Wang et al. Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle J Clin Invest 99 1997 163-168
19. C.H. Fang B.G. Li D.R. Fischer et al. Burn injury upregulates the activity and gene expression of the 20S proteasome in rat skeletal muscle Clin Sci 99 2000 181-187
20. F. Hammarqvist J-L. Luo I.A. Cotgreave K. Andersson J. Wernerman Skeletal muscle glutathione is depleted in critically ill patients Crit Care Med 25 1 1997 78-84
21. A.L. Serrano M. Pérez A. Lucía J.L. Chicharro E. Quiroz-Rothe J.L.L. Rivero Immunolabelling, histochemistry and in situ hybridisation in human skeletal muscle fibres to detect myosin heavy chain expression at the protein and mRNA level J Anat 199 2001 329-337
22. M. Bossola M. Muscaritoli P. Costelli et al. Increased muscle proteasome activity correlates with disease severity in gastric cancer patients Ann Surg 237 3 2003 384-389
23. D. Fischer X. Sun G. Gang T. Pritts P.O. Hasselgren The gene expression of ubiquitin ligase E3alpha is upregulated in skeletal muscle during sepsis in rats-potential role of glucocorticoids Biochem Biophys Res Commun 267 2000 504-508
24. S.H. Lecker V. Solomon S.R. Price Y.T. Kwon W.E. Mitch A.L. Goldberg Ubiquitin conjugation by the N-end rule pathway and mRNA for its components increase; in muscles of diabetic rats J Clin Invest 104 1999 1411-1420
25. N. Schimbara E. Orino S. Sone et al. Regulation of gene expression of proteasomes (multi-protease complexes) during growth and differentiation of human hematopoietic cells J Biol Chem 267 1992 18100-18109
26. B. Dahlmann T. Ruppert P.M. Kloetzel L. Kuehn Subtypes of 20S proteasomes from skeletal muscle Biochimie 83 2001 295-299
27. P. Brooks R.Z. Murray G.G.F. Mason K.B. Hendil A.J. Rivett Association of immunoproteasomes with the endoplasmic reticulum Biochem J 352 2000 611-615
28. S. Merforth L. Kuehn A. Osmers B. Dahlmann Alteration of 20S proteasome-subtypes and proteasome activator PA28 in skeletal muscle of rat after induction of diabetes mellitus Int J Biochem Cell Biol 35 5 2003 740-748
29. S.R. Price W.E. Mitch Mechanisms stimulating protein degradation to cause muscle atrophy Curr Opin Clin Nutr Metab Care 1 1998 79-83
30. M. Llovera N. Carbó J. López-Soriano et al. Different cytokines modulate ubiquitin gene expression in rat skeletal muscle Cancer Lett 133 1998 83-87
31. K. Nagaraju Immunological capabilities of skeletal muscle cells Acta Physiol Scand 171 2001 215-223
32. P. Englund I. Nennesmo L. Klareskog I.E. Lundberg Interleukin-1α expression in capillaries and major histocompatibility complex class I expression in type II muscle fibers from polymyositis and dermatomyositis patients Arthritis Rheum 46 4 2002 1044-1055
33. M.A.J. De Letter P.A. van Dorn H.F.J. Savelkoul et al. Critical illness polyneuropathy and myopathy (CIPNM): Evidence for local immune activation by cytokine-expression in the muscle tissue J Neuroimmunol 106 2000 206-213
34. P. Bazzi M. Moggio A. Prelle et al. Critially ill patients: immunological evidence of inflammation in muscle biopsy Clin Neuropathol 18 1 1999 23-30
35. V. Solomon A.L. Goldberg Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts J Biol Chem 271 43 1996 26690-26697