In vivo and in vitro patch-clamp recording analysis of the process of sensory transmission in the spinal cord and sensory cortex

Journal of Physiological Anthropology and Applied Human Science

Volumn 24, Issue 1, 2005, Pages 93-97

  Yoshimura, Megumu ^a   Doi, Atsushi ^a   Mizuno, Masaharu ^b   Furue, Hidemasa ^a   Katafuchi, Toshihiko ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Chronic pain; In vivo patch clamp; Sensory cortex; Substantia gelatinosa; Thalamus

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; IN VIVO STUDY; MALE; NERVE CELL; NOCICEPTIVE STIMULATION; NONHUMAN; OSCILLATION; PATCH CLAMP; RAT; RECORDING; SENSORY CORTEX; SENSORY STIMULATION; SIGNAL TRANSDUCTION; SOMATOSENSORY SYSTEM; SPINAL CORD DORSAL HORN; STIMULUS; SYNAPSE; THALAMUS;

ANIMALS; MALE; PAIN, INTRACTABLE; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SUBSTANTIA GELATINOSA; SYNAPTIC TRANSMISSION;

EID: 15244341541     PISSN: 13453475     EISSN: None     Source Type: Journal    
DOI: 10.2114/jpa.24.93     Document Type: Article

References (13)

1. Yoshimura M, Jessell TM (1989) Primary afferent-evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro. J Neurophyiol 62: 96-108
2. Furue H, Narikawa K, Kumamoto E, Yoshimura M (1999) Responsiveness of rat subsantia gelatinosa neurones to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording. J Physiol 521: 529-535
3. Nakatsuka T, Park J-S, Kumamoto E, Tamaki T, Yoshimura M (1999) Plastic changes in sensory inputs to rat substantia gelatinosa neurons following peripheral inflammation. Pain 82: 39-47
4. Ito A, Kumamoto E, Takeda M, Takeda M, Shibata K, Sagai H, Yoshimura M (2000) Mechanisms for ovariectomy-induced hyperalgesia and its relief by calcitonin: participation of 5-HT1A-like receptor on C-afferent terminals in substantia gelatinosa of the rat spinal cord. J Neurosci 20: 6302-6308
5. Moore KA, Kohno T, Karchewski LA, Scholz J, Baba H, Woolf CJ (2002) Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord. J Neurosci 22: 6724-6731
6. Randic M, Jiang MC, Cerne R (1993) Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord. J Neurosci 12: 5228-5241
7. Shigeto H, Morioka T, Hisada K, Nishio S, Ishibashi H, Kira D, Tobimatsu S, Kato M (2002) Feasibility and limitations of magnetoencephalographic detection of epileptic discharges: simultaneous recording of magnetic fields and electrocorticography. Neurol Res 24: 531-536
8. Hofbauer RK, Rainville P, Duncan GH, Bushnell MC (2001) Cortical representation of the sensory dimension of pain. J Neurophysiol 86:402-411
9. Yoshimura M, Nishi S (1993) Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: pharmacological properties of synaptic currents. Neuroscience 53: 519-526
10. Okamoto M, Baba H, Goldstein PA, Higashi H, Shimoji K, Yoshimura M (2001) Functional reorganization of sensory pathways in the rat spinal dorsal horn following peripheral nerve injury. J Physiol 532: 241-250
11. Jackman A, Fitzgerald M (2000) The development of peripheral hindlimb and central spinal cord innevation by subpopulations of dorsal root ganlion cells in the embryonic rat. J Comp Neurol 418: 281-298
12. Inui K, Wang X, Qiu Y, Nguyen BT, Ojima S, Tamura Y, Nakata H, Wasaka T, Tran TD, Kakigi R (2003) Pain processing within the primary somatosensory cortex in humans. Eur J Neurosci 18: 2859-2866
13. Kenshalo DR, Iwata K, Sholas M, Thomas DA (2000) Response properties and organization of nociceptive neurons in area 1 of monkey primary somatosensory cortex. J Neurophysiol 84: 719-729