Multiple gastric carcinoids and endocrine cell micronests in type a gastritis: Nuclear morphometric and immunohistochemical analysis

Oncology Reports

Volumn 13, Issue 3, 2005, Pages 397-404

  Iwai, Kei Ichiro ^a   Yao, Takashi ^a   Nakamura, Shotaro ^a   Matsumoto, Takayuki ^a   Nishiyama, Ken Ichi ^a   Iida, Mitsuo ^a   Tsuneyoshi, Masazumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

bcl 2; Endocrine cell micronest; Gastric carcinoid; Ki 67; Nuclear morphometry; p53; Type A gastritis

Indexed keywords

PROTEIN BCL 2; TUMOR MARKER;

ADULT; AGED; ARTICLE; AUTOMATION; BIOPSY; BIOSYNTHESIS; CARCINOID; CELL NUCLEUS; CELL TRANSFORMATION; DIFFERENTIAL DIAGNOSIS; ENTEROCHROMAFFIN LIKE CELL; FEMALE; GASTRITIS; GENE EXPRESSION PROFILING; HUMAN; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PATHOLOGY; RETROSPECTIVE STUDY; STOMACH; STOMACH TUMOR; ULTRASTRUCTURE;

ADULT; AGED; AUTOMATION; BIOPSY; CARCINOID TUMOR; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; DIAGNOSIS, DIFFERENTIAL; ENTEROCHROMAFFIN-LIKE CELLS; FEMALE; GASTRITIS; GENE EXPRESSION PROFILING; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-BCL-2; RETROSPECTIVE STUDIES; STOMACH; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 15044364145     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.13.3.397     Document Type: Article

References (39)

1. Black WC and Haffner HE: Diffuse hyperplasia of gastric argyrophil cells and multiple carcinoid tumors: A historical and ultrastructural study. Cancer 21: 1080-1099, 1968.
2. Rindi G, Luinetti O, Cornaggia M, Capella C and Solcia E: Three subtypes of gastric argyrophil carcinoids and the gastric neuroendocrine carcinoma: a clinicopathological study. Gastroenterology 104: 994-1006, 1993. (Pubitemid 23090750)
3. Rindi G, Bordi C, Rappel S, La Rosa S, Stolte M and Solcia E: Gastric carcinoids and neuroendocrine carcinomas: pathologenesis, pathology and behavior. World J Surg 20: 168-172, 1996. (Pubitemid 26069482)
4. Rindi G, Azzoni C, Rosa SL, et al: ECL cell tumor and poorly differentiated endocrine carcinoma of the stomach: prognostic evaluation by pathological analysis. Gastroenterology 116: 532-542, 1999. (Pubitemid 29106760)
5. Strickland RG and Mackary IR: A reappraisal of the nature and significance of chronic atrophic gastritis. Am J Dig Dis 18: 426-440, 1973.
6. Dixon MF, Genta RM, Yardley JH and Correa P: Classification and grading of gastritis. The updated Sydney system. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 20: 1161-1181, 1996.
7. Itsuno M, Watanabe H, Iwafuchi M, et al: Multiple carcinoids and endocrine cell micronests in type A gastritis: Their morphology, histogenesis and natural history. Cancer 63: 881-890, 1989. (Pubitemid 19063195)
8. Solcia E, Bordi C, Creutzfeldt W, et al: Histopahtological classification of nonantral gastric endocrine growths in man. Digestion 41: 185-200, 1988. (Pubitemid 19070318)
9. Reinecke P and Borchard F: Pattern of gastric endocrine cells in microcarcinoidosis: an immunohistochemical study of 14 gastric biopsies. Virchows Arch A Pathol Ant Histopathol 428: 237-241, 1996.
10. Grigioni WF, Caletti GC, Gabrielli M, Marrano D, Villanacci V and Mancini A: Gastric carcinoids of ECL cells: Pathological and clinical analysis of eight cases. Acta Pathol Jpn 35: 361-375, 1985. (Pubitemid 15100016)
11. Borch K, Renvall H, Kullman E and Wilander E: Gastric carcinoid associated with the syndrome of hypergastrinemic atrophic gastritis: a prospective analysis of 11 cases. Am J Surg Pathol 11: 435-444, 1987. (Pubitemid 17085829)
12. Annibale B, Azzoni C, Corleto Vito D, et al: Atrophic body gastritis patients with enterochromaffin-like cell dysplasia are increased risk for the development of type 1 gastric carcinoid. Eur J Gastroenterol Hepatol 13: 1449-1456, 2001. (Pubitemid 33151497)
13. Dayal Y: Recognition and the histopathologic classification of ECL cell proliferations. Yale J Biol Med 71: 257-272, 1998.
14. Baak JP, Kurver PH, De Snoo-Niewlaat AJ, De Graef S, Makkink B and Boon ME: Prognostic indicators in breast cancer: Morphometric methods. Histopathol 6: 327-339, 1982. (Pubitemid 12123139)
15. Epstein JI, Berry SJ and Eggleston JC: Nuclear roundness factor: A predictor of progression in untreated stage A2 prostate cancer. Cancer 54: 1666-1671, 1984. (Pubitemid 14006231)
16. Tosi P, Luzi P, Baak PJA, et al: Nuclear morphometory as an important prognostic factor in stage I renal cell carcinoma. Cancer 58: 2512-2518, 1986. (Pubitemid 17191616)
17. Ooms EC, Essed E, Veldhuizen RW, Alons CL, Kurver P and Boon ME: The prognostic significance of morphometory in T1 bladder tumors. Histopathol 5: 311-318, 1981. (Pubitemid 11039346)
18. Blomjous CE, Schipper NW, Vos W, Baak JP, de Voogt HJ and Meijer CJ: Comparison of quantitative and classic prognosticators in urinary bladder carcinoma: A multivariate analysis of DNA flow cytometric, nuclear morphometric, and clinicopathological features. Virchows Arch A Pathol Ant Histopathol 415: 421-428, 1989.
19. Nishihara K and Tsuneyoshi M: Papillary cystic tumors of the pancreas: An analysis by nuclear morphometory. Virchows Arch A Pathol Anat Histopathol 422: 211-217, 1993. (Pubitemid 23131502)
20. Noguchi S, Tamiya S, Nagosi M, Suita S, Fukuda T and Tsuneyoshi M: Nuclear morphometry and the M1B-1 Index in Rhabdomyosarcoma. Mod Pathol 9: 253-260, 1996. (Pubitemid 26126551)
21. Tan PH, Goh BB, Chiang G and Bay BH: Correlation of nuclear morphometry with pathologic parameters in ductal carcinoma in situ of breast. Mod Pathol 14: 937-941, 2001. (Pubitemid 32976779)
22. Helander HF: Oxyntic mucosa histology in Omeplazole-treated patients suffering from duodenal ulcer or Zollinger-Ellison syndrome. Digestion 35 (suppl 1): 123-129, 1986.
23. Dayal Y, Berlin RG, Bhatnagar R and LaMont B: Correlation between morphometry and qualitative scoring of gastric endocrine cells. Lab Invest 64: A35, 1991.
24. D'Adda, Pilato FP, Sivelli R, Azzoni C, Sianesi M and Bordi C: Gastric carcinoid tumor and its precursor lesions: ultrastructural study of a case before and after antrectomy. Arch Pathol Lab Med 118: 658-663, 1993.
25. Nojiri T and Ikegami M: Multiple minute carcinoids in type A gastritis: Attempt at 3-D reconstruction. Pathol Int 51: 504-510, 2001. (Pubitemid 32744433)
26. Nishikura K, Watanabe H, Iwafuchi M, et al. Historical overview of the classification of gastric carcinoid. Stomach Intestine 35: 1349-1354, 2000. (In Japanese).
27. Gaulard P, d'Agay M-F, Peuchmaur M, et al: Expression of the bcl-2 gene product in follicular lymphoma. Am J Pathol 140: 1089-1095, 1992.
28. Nakamura S, Akazawa K, Kinukawa N, Yao T and Tsuneyoshi M: Inverse correlation between the expression of bcl-2 and p53 proteins in primary gastric lymphoma. Human Pathol 27: 225-233, 1996. (Pubitemid 26078900)
29. Kolodziejczyk P, Yao T, Oya M. Nakamura S, Utsunomiya T, Ishikawa T and Tsuneyoshi M: Long term follow-up study of patients with gastric adenomas with malignant transformation. Cancer 74: 2896-2907, 1994.
30. Bhagarva V, Kell DL, van de Rijn M and Warnke RA: bcl immunoreactivity in breast carcinoma correlates with hormone receptor positivity. Am J Pathol 145: 535-540, 1994. (Pubitemid 24285961)
31. Hockenbery DM, Zutter M, Hickey W, Nahm M and Korsmeyer SJ: BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 88: 6961-6965, 1991. (Pubitemid 21915069)
32. Moyana TN, Xiang J, Senthilselvan A and Kulaga A: The spectrum of neuroendocrine differentiation among gastrointestinal carcinoids: Importance of histologic grading, MIB-1, p53, and bcl-2 immunoactivity. Arch Pathol Lab Med 124: 570-576, 2000. (Pubitemid 30210990)
33. Azzoni C, Doglioni C, Viale G, et al: Involvement of BCL-2 oncoprotein in the development of enterochromaffin-like cell gastric carcinoids. Am J Surg Pathol 20: 433-441, 1996.
34. Solcia E, Rindi G, Fiocca R, Villani L, Riva C and Capella C: Endocrine proliferations and carcinoids in hypergastrinemia. In: Gastrin. Walsh JH (ed). Raven Press, New York, pp361-371, 1993.
35. Richards AT, Hinder RA and Harrison AC: Gastric carcinoid tumor asspciated with hypergastrinemia and pernicious anemia-regression of tumors antrectomy. A case report. S A fr Med J 72: 51-53, 1987.
36. Eckhauser FE, Lloyd RV, Thompson NW, Raper SE and Vinik AI: Antrectomy for multicentric, argyrophil gastric carcinoids: a preliminary report. Surgery 104: 1046-1053, 1988. (Pubitemid 19011985)
37. Kern SE, Yardley JH, Lazenby AJ, Boitnott JK, Yang VW, Bayless TM and Sitzmann JV: Reversal by antrectomy of endocrine cell hyperplasia in the gastric body in pernicious anemia: a morphometric study. Mod Pathol 3: 561-566, 1990.
38. Hirschowitz BI, Griffith J, Pellegrin D and Cummings OW: Rapid regression of enterochromaffin-like cell gastric carcinoids in pernicious anemia after antrectomy. Gastroenterology 102: 1409-1418, 1992.
39. Hagarty S, Huttner I, Shibata H and Katz S: Gastric carcinoid tumors and pernicious anemia: case report and review of the literature. Can J Gastroenterol 14: 241-245, 2000. (Pubitemid 30182428)