Structure-based design of derivatives of tyropeptin A as the potent and selective inhibitors of mammalian 20S proteasome

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 7, 2005, Pages 1867-1871

  Momose, Isao ^a   Umezawa, Yoji ^b   Hirosawa, Sehei ^c   Iinuma, Hironobu ^b   Ikeda, Daishiro ^a  

^a Numazu Bio Medical Research Institute   (Japan)

^b INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^c Microbial Chemistry Research Center   (Japan)

Author keywords

Proteasome inhibitor

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CHYMOTRYPSIN; PROTEASOME INHIBITOR; TP 101; TP 102; TP 103; TP 104; TP 105; TP 106; TP 107; TP 108; TP 109; TP 110; TP 111; TRYPSIN; TYROPEPTIN A; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY;

KITASATOSPORA; MAMMALIA;

EID: 15044349908     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.013     Document Type: Article

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