Inhibitors of islet amyloid polypeptide fibrillogenesis, and the treatment of type-2 diabetes

Letters in Peptide Science

Volumn 10, Issue 5-6, 2003, Pages 545-551

  Scrocchi, Louise A ^a   Chen, Yan ^a   Wang, Feng ^a   Han, Kyung ^a   Ha, Katherine ^a   Wu, Ling ^a   Fraser, Paul E ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

cells; Amyloid fibrils; Apoptosis; Circular dichroism; Diabetes; Electron microscopy; Islet amyloid polypeptide

Indexed keywords

AMINO ACID; AMYLOID PROTEIN; GLYCYLALANYLISOLEUCYLLEUCYLSERYLSERINE; HUMAN ISLET AMYLOID POLYPEPTIDE INHIBITOR; PROTEIN INHIBITOR; SERYLASPARAGINYLASPARAGINYLPHENYLALANYLGLYCYLALANINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; CELL CULTURE; CELL FUNCTION; CELL SURVIVAL; CORRELATION ANALYSIS; CYTOTOXICITY; DENSITY; ELECTRON MICROSCOPY; FIBER; HUMAN; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS; PANCREAS ISLET CELL; PEPTIDE ANALYSIS; POLYMERIZATION; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE; STAINING; STATISTICAL SIGNIFICANCE;

EID: 15044344416     PISSN: 09295666     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02442587     Document Type: Article

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