Protective effect of triflusal and its main metabolite HTB in an in vitro model of anoxia-reoxygenation in rat brain slices: Comparison with acetylsalicylic and salicylic acids

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 371, Issue 1, 2005, Pages 81-88

  Gonzalez Correa J A ^a   Arrebola, M M ^a   Urena I M ^a   Ruiz Villafranca, D ^a   Munoz Marin J ^a   Guerrero, A ^a   Sanchez De La Cuesta F ^a   De La Cruz, J P ^a  

^a Facultad de Medicina   (Spain)

Author keywords

Acetylsalicylic acid; Brain anoxia reoxygenation; Nitric oxide; Oxidative stress; Triflusal

Indexed keywords

2 HYDROXY 4 (TRIFLUOROMETHYL)BENZOIC ACID; ACETYLSALICYLIC ACID; BIOCHEMICAL MARKER; DRUG METABOLITE; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; NITRATE; NITRIC OXIDE; NITRITE; PROSTAGLANDIN E2; SALICYLIC ACID; TRIFLUSAL; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOMECHANICS; BRAIN HYPOXIA; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; EXPERIMENTAL MODEL; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; REOXYGENATION;

ANIMALS; ASPIRIN; BRAIN CHEMISTRY; DINOPROSTONE; GLUTATHIONE; HYPOXIA, BRAIN; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; MALE; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PLATELET AGGREGATION INHIBITORS; RATS; RATS, WISTAR; REPERFUSION INJURY; SALICYLATES; SALICYLIC ACIDS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 15044340682     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-004-1001-y     Document Type: Article

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