Manipulation of local disposition and gene expression characteristics of plasmid DNA following intramuscular administration by complexation with cationic macromolecule

International Journal of Pharmaceutics

Volumn 293, Issue 1-2, 2005, Pages 291-301

  Kawase, Atsushi ^a   Kobayashi, Naoki ^a   Isaji, Keiko ^a   Nishikawa, Makiya ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cationic macromolecule; Complex; Disposition; DNA vaccine; Gene expression; Plasmid DNA

Indexed keywords

BOVINE SERUM ALBUMIN; DRUG CARRIER; IMMUNOGLOBULIN G ANTIBODY; PLASMID DNA;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; GENE EXPRESSION; GENETIC MANIPULATION; IMMUNE RESPONSE; INJECTION SITE; LYMPH NODE; MACROMOLECULE; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 15044339856     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.12.011     Document Type: Article

References (25)

1. J.S. Boyle, A. Silva, J.L. Brady, and A.M. Lew DNA immunization: induction of higher avidity antibody and effect of route on T-cell cytotoxicity Proc. Natl. Acad. Sci. U.S.A. 94 1997 14626 14631
2. V.W. Bramwell, J.E. Eyles, S. Somavarapu, and H.O. Alpar Liposome/DNA complexes coated with biodegradable PLA improve immune responses to plasmid encoding hepatitis B surface antigen Immunology 106 2002 412 418
3. S.S. Diebold, M. Kursa, E. Wagner, M. Cotton, and M. Zenke Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells J. Biol. Chem. 274 1999 19087 19094
4. J.J. Donnelly, J.B. Ulmer, and M.A. Liu DNA vaccines Life Sci. 60 1997 163 172
5. G.S. Gilkeson, A.M. Pippen, and D.S. Pisetsky Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA J. Clin. Invest. 95 1995 1398 1402
6. G.S. Gilkeson, P. Ruiz, A.M. Pippen, A.L. Alexander, J.B. Lefkowith, and D.S. Pisetsky Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA J. Exp. Med. 183 1996 1389 1397
7. G. Hartmann, and A.M. Krieg CpG DNA and LPS induce distinct patterns of activation in human monocytes Gene Ther. 6 1999 893 903
8. F. Heinz, and S.O. Harold Esterification of proteins with alcohols of low molecular weight J. Biol. Chem. 161 1945 259 268
9. K. Kawabata, Y. Takakura, and M. Hashida The fate of plasmid DNA after intravenous injection in mice: involvement of scavenger receptors in its hepatic uptake Pharm. Res. 12 1995 825 830
10. A. Kawase, T. Nomura, K. Yasuda, N. Kobayashi, M. Hashida, and Y. Takakura Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice J. Pharm. Sci. 92 2003 1295 1304
11. N. Kobayashi, T. Kuramoto, K. Yamaoka, M. Hashida, and Y. Takakura Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures J. Pharmacol. Exp. Ther. 297 2001 853 860
12. M. Kwissa, von, K. Kampen, R. Zurbriggen, R. Gluck, J. Reimann, and R. Schirmbeck Efficient vaccination by intradermal or intramuscular inoculation of plasmid DNA expressing hepatitis B surface antigen under desmin promoter/enhancer control Vaccine 18 2000 2337 2344
13. H.T. Maecker, D.T. Umetsu, R.H. DeKruyff, and S. Levy DNA vaccination with cytokine fusion constructs biases the immune response to ovalbumin Vaccine 15 1997 1687 1696
14. J.P. Mandell, and A.D. Hershey A fractionating column for analysis of nucleic acids Anal. Biochem. 1 1960 66 77
15. T.M. Pertmer, T.R. Roberts, and J.R. Haynes Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery J. Virol. 70 1996 6119 6125
16. M. Sedegah, R. Hedstrom, P. Hobart, and S.L. Hoffman Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein Proc. Natl. Acad. Sci. U.S.A. 91 1994 9866 9870
17. Z. Shen, G. Reznikoff, G. Dranoff, and K.L. Rock Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules J. Immunol. 158 1997 2723 2730
18. M. Singh, M. Briones, G. Ott, and D. O'Hagan Cationic microparticles: a potent delivery system for DNA vaccines Proc. Natl. Acad. Sci. U.S.A. 97 2000 811 816
19. D.C. Tang, M. DeVit, and S.A. Johnston Genetic immunization is a simple method for eliciting an immune response Nature 356 1992 152 154
20. N.L. Tilney Patterns of lymphatic drainage in the adult laboratory rat J. Anat. 109 1971 369 383
21. C.A. Torres, A. Iwasaki, B.H. Barber, and H.L. Robinson Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations J. Immunol. 158 1997 4529 4532
22. J.B. Ulmer, J.J. Donnelly, S.E. Parker, G.H. Rhodes, P.L. Felgner, V.J. Dwarki, S.H. Gromkowski, R.R. Deck, C.M. DeWitt, and A. Friedman Heterologous protection against influenza by injection of DNA encoding a viral protein Science 259 1993 1745 1749
23. J.A. Wolff, R.W. Malone, P. Williams, W. Chong, G. Acsadi, A. Jani, and P.L. Felgner Direct gene transfer into mouse muscle in vivo Science 247 1990 1465 1468
24. J.A. Wolff, M.E. Dowty, S. Jiao, G. Repetto, R.K. Berg, J.J. Ludtke, P. Williams, and D.B. Slautterback Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle J. Cell. Sci. 103 1992 1249 1259
25. Z. You, X. Huang, J. Hester, H.C. Toh, and S.Y. Chen Targeting dendritic cells to enhance DNA vaccine potency Cancer Res. 61 2001 3704 3711