Developmental characteristics of epileptiform activity in immature rat neocortex: A comparison of four in vitro seizure models

Developmental Brain Research

Volumn 128, Issue 2, 2001, Pages 113-120

  Wong, Michael ^a,b   Yamada, Kelvin A ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST LOUIS CHILDREN S HOSPITAL   (United States)

Author keywords

Development; Epilepsy; Neocortex; Rat; Seizure; Synaptic transmission

Indexed keywords

3 AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOPYRIDINE; GLUTAMIC ACID; MAGNESIUM; PICROTOXIN;

AGE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPILEPTIC DISCHARGE; GABAERGIC SYSTEM; IN VITRO STUDY; NEOCORTEX; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; SEIZURE; SEIZURE SUSCEPTIBILITY; SYNAPTIC POTENTIAL;

4-AMINOPYRIDINE; AGE FACTORS; ANIMALS; CONVULSANTS; EPILEPSY; GABA ANTAGONISTS; MAGNESIUM; MEMBRANE POTENTIALS; NEOCORTEX; ORGAN CULTURE TECHNIQUES; ORGANOPHOSPHORUS COMPOUNDS; PICROTOXIN; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTIC TRANSMISSION;

EID: 0035968044     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(01)00149-3     Document Type: Article

References (28)

1. O in the human epileptogenic neocortex maintained in vitro
2. Epileptiform discharges and a synchronous GABAergic potential induced by 4-aminopyridine in the rat immature hippocampus
3. A, NMDA and AMPA receptors: A developmentally regulated 'menage a trois'
4. Temporal lobe epilepsy in infants and children
5. Epileptiform activity induced by 4-aminopyridine in immature hippocampus
6. Effects of antiepileptic drugs on 4-aminopyridine-induced epileptiform activity in young and adult rat hippocampus
7. B inhibition in rat somatosensory cortex
8. B-mediated inhibitions in the CA3 hippocampal region of the rat
9. 2+ induced epileptiform activity in rat hippocampal and enthorhinal cortex slices during adolescence
10. Mechanisms of neocortical epileptogenesis in vitro
11. Spontaneous ictal-like discharges and sustained potential shifts in the developing rat neocortex
12. 2+ changes during epileptiform discharges in the immature rat neocortex
13. Alterations in the microenvironment during spreading depression associated with epileptiform activity in the immature neocortex
14. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984
15. Epileptogenesis in immature neocortical slices induced by 4-aminopyridine
16. Cellular and synaptic physiology and epileptogenesis of developing rat neocortical neurons in vitro
17. Generation and propagation of 4-AP-induced epileptiform activity in neonatal intact limbic structures in vitro
18. Epileptiform activity induced by 4-aminopyridine in guinea-pig and neocortices
19. Comparison of antagonist potencies at pre- and post-synaptic GABA(B) receptors at inhibitory synapses in the CA1 region of the rat hippocampus
20. 4-aminopyridine-induced spreading depression episodes in immature hippocampus: Developmental and pharmacological characteristics
21. Developmental features of 4-aminopyridine induced epileptogenesis
22. Differential bicuculline-induced epileptogenesis in rat neonatal, juvenile and adult CA3 pyramidal neurons in vitro
23. Development of excitatory and inhibitory postsynaptic potentials in the rat neocortex
24. B receptors in convulsant-induced epileptiform activity in rat neocortex in vitro
25. Penicillin-induced epileptogenesis in immature rat CA3 hippocampal pyramidal cells
26. 2+-free medium
27. Age dependence of NMDA receptor involvement in epileptiform activity in rat hippocampal slices
28. Cyclosporine induces epileptiform activity in an in vitro seizure model