AG-041R, a novel indoline-2-one derivative, stimulates chondrogenesis in a bipotent chondroprogenitor cell line CL-1

Osteoarthritis and Cartilage

Volumn 13, Issue 4, 2005, Pages 287-296

  Kitamura, Hidetomo ^a   Okazaki, Makoto ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

AG 041R; Chondrogenesis; CL 1; MAP kinases; TGF

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; 1 [2,3 DIHYDRO 1 (2' METHYLPHENACYL) 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL] 3 (3 METHYLPHENYL)UREA; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 [1 (2,2 DIETHOXYETHYL)] 3 [(4 METHYLPHENYL)AMINOCARBONYLMETHYL] 3 [(4 METHYLPHENYL)UREIDO]INDOLINE 2 ONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AG 041; AGGRECAN; ALCIAN BLUE; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; COLLAGEN TYPE 2; GASTRIN ANTAGONIST; INDOLE DERIVATIVE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTRALIZING ANTIBODY; PROTEIN P42; PROTEIN P44; RIBOSOME RNA; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL GROWTH; CHONDROGENESIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HISTOLOGY; MOUSE; NONHUMAN; NORTHERN BLOTTING; PH; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CHONDROCYTES; CHONDROGENESIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; INDOLES; MESENCHYMAL STEM CELLS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTOR, CHOLECYSTOKININ B; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 14944385418     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.12.009     Document Type: Article

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