AG-041R, a novel indoline-2-one derivative, induces systemic cartilage hyperplasia in rats

European Journal of Pharmacology

Volumn 418, Issue 3, 2001, Pages 225-230

  Kitamura, Hidetomo ^a   Kato, Atsuhiko ^a   Esaki, Toru ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Indoline 2 one derivative; Systemic cartilage hyperplasia

Indexed keywords

1 (2,2 DIETHOXYETHYL) 3 [(4 METHYLPHENYL)AMINOCARBONYLMETHYL] 3 [(4 METHYLPHENYL)UREIDO]INDOLINE 2 ONE; AG 041R; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; GASTRIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CHONDROGENESIS; CHONDROPATHY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG SYNTHESIS; EAR CARTILAGE; FEMUR CONDYLE; HISTOPATHOLOGY; HYPERPLASIA; INTERVERTEBRAL DISK; KNEE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STERNUM; TRACHEA;

ADMINISTRATION, ORAL; ANIMALS; CARTILAGE; CHONDROCYTES; FEMUR; HYPERPLASIA; INDOLES; INJECTIONS, INTRA-ARTICULAR; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPECIFIC PATHOGEN-FREE ORGANISMS; TRACHEA; XIPHOID BONE;

EID: 0035957713     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00957-8     Document Type: Article

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