Characterization of an experimental venous thrombus model with MRI, phlebography and histology;Charakterisierung eines experimentellen venösen thrombosemodells mittels MRT, phlebographie und histologie

RoFo Fortschritte auf dem Gebiet der Rontgenstrahlen und der Bildgebenden Verfahren

Volumn 177, Issue 3, 2005, Pages 411-419

  Schmitz, Stephan A ^a,b   Schiffler, S ^a   Gust, R ^a   Winterhalter, S ^a   Coupland, S E ^a   Wolf, K J ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Experimental venous thrombosis; Magnetic resonance imaging; Thrombus imaging; Thrombus organization; Thrombus specific contrast agents

Indexed keywords

CONTRAST MEDIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APPARATUS; ARTICLE; BLADDER SPHINCTER; BLOOD VESSEL OCCLUSION; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DISEASE MODEL; EVALUATION; HISTOLOGY; HYPERCOAGULABILITY; IMAGE ANALYSIS; IMAGE DISPLAY; IMAGE QUALITY; IMAGE RECONSTRUCTION; INTERMETHOD COMPARISON; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHLEBOGRAPHY; PRIORITY JOURNAL; RABBIT; SIGNAL DETECTION; VEIN THROMBOSIS;

ANIMALS; CONTRAST MEDIA; DATA INTERPRETATION, STATISTICAL; DISEASE MODELS, ANIMAL; IMAGING, THREE-DIMENSIONAL; JUGULAR VEINS; MAGNETIC RESONANCE IMAGING; PHLEBOGRAPHY; RABBITS; TIME FACTORS; VENOUS THROMBOSIS;

EID: 14944372112     PISSN: 14389029     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-813903     Document Type: Article

References (30)

1. Braunwald E. Shattuck lecture - cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities. N Engl J Med 1997; 337: 1360-1369
2. Moody AR, Pollock JG, O'Connor AR et al. Lower-limb deep venous thrombosis: direct MR imaging of the thrombus. Radiology 1998; 209: 349-355
3. Fuster V, Fallon JT, Badimon JJ et al. The unstable atherosclerotic plaque: clinical significance and therapeutic intervention. Thromb Haemost 1997; 78: 247-255
4. Erdman WA, Weinreb JC, Cohen JM et al. Venous thrombosis: clinical and experimental MR imaging. Radiology 1986; 161: 233-238
5. Vorwerk D, Vollmer B, Handt S et al. Laserthermische Venenobliteration: experimentelle Ergebnisse am Rattenmodell. Fortschr Röntgenstr 1994; 160: 84-88
6. Tacke J, Vorwerk D, Klosterhalfen B et al. Experimentelles Modell einer früh-chronischen Beckenvenenthrombose mit Okklusionsspiralen und Thrombi. Fortschr Röntgenstr 1998; 169: 645-648
7. Leu AJ, Leu HJ. Spezielle Probleme bei der histologischen Altersbestimmung von Thromben und Emboli. Pathologe 1989; 10: 87-92
8. Mann KG. Thrombosis: theoretical considerations. Am J Clin Nutr 1997; 65: 1657S-1664S
9. Leu HJ. Histologische Altersbestimmung von arteriellen und venösen Thromben und Emboli. Vasa 1973; 2: 265-274
10. Stehbens WE. Thrombosis and vascular trauma. In: Stehbens WE, Lie JT (Hrsg). Vascular Pathology. London: Chapman & Hall, 1995: 63-87
11. Flacke S, Fischer S, Scott MJ et al. Novel mri contrast agent for molecular imaging of fibrin: implications for detecting vulnerable plaques. Circulation 2001; 104: 1280-1285
12. Johansson LO, Bjornerud A, Ahlstrom HK et al. A targeted contrast agent for magnetic resonance imaging of thrombus: implications of spatial resolution. J Magn Reson Imaging 2001; 13: 615-618
13. Schmitz SA, Winterhalter S, Schiffler S et al. USPIO-enhanced direct MR imaging of thrombus: preclinical evaluation in rabbits. Radiology 2001; 221: 237-243
14. Cyrus T, Winter PM, Abendschein D et al. Molecular Imaging of avB3-Integrin and Collagen-III Targeted Nanoparticles in Pig Carotids Following Angioplasty. The 2nd Annual Meeting of the Society of Molecular Imaging 2003
15. Kirchhof K, Sikinger M, Welzel T et al. Hängt das Ergebnis einer Thrombolyse mit rekombinantem Gewebe-Plasminogenaktivator (rt-PA) beim Kaninchen vom Erythrozyten- und Fibringehalt eines Thrombus ab? Fortschr Röntgenstr 2004; 176: 98-105
16. Müller-Hülsbeck S, Jahnke T, Stolzmann P et al. Ein neuartiges Konzept der stentgeschützten Karotisangioplastie: Eine Kadaverstudie. Fortschr Röntgenstr 2003; 175: 1634-1638
17. Kirchhof K, Mecke C, Lichy C et al. Die Röntgendichte am Ort thrombembolischer zerebraler Gefäßverschlüsse: Prognostischer Faktor für eine Lysetherapie? Fortschr Röntgenstr 2003; 175: 1130-1137
18. Mugler JP, Brookeman JR. Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magn Reson Med 1990; 15: 152-157
19. Moody AR, Liddicoat A, Krarup K. Magnetic resonance pulmonary angiography and direct imaging of embolus for the detection of pulmonary emboli. Invest Radiol 1997; 32: 431-440
20. Moody AR, Murphy RE, Morgan PS et al. Characterization of complicated carotid plaque with magnetic resonance direct thrombus imaging in patients with cerebral ischemia. Circulation 2003; 107: 3047-3052
21. Frahm J, Haase A, Matthaei D. Rapid three-dimensional MR imaging using the FLASH technique. J Comput Assist Tomogr 1986; 10: 363-368
22. Irniger W. Histologische Altersbestimmung von Thromben und Embolien. Virchows Arch path Anat 1963; 336: 220-237
23. Wessler S. Thrombosis in the presence of vascular stasis. Am J Med 1962; 33: 648-666
24. Gibbs N. Venous thrombosis of the lower limbs with particular reference to bed-rest. British Journal of Surgery 1960; 45: 209-236
25. Hadfield G. Thrombosis. Ann Roy Coll Surg Engl 1950; 6: 219-234
26. el Kouri D, Dupas B, Peltier P et al. Experimental venous thrombosis: what animal model? Int Angiol 1992; 11: 304-308
27. Rekhter MD. How to evaluate plaque vulnerability in animal models of atherosclerosis? Cardiovasc Res 2002; 54: 36-41
28. Schmitz SA, Hansel J, Wagner S et al. SPIO-unterstützte MR-Angiographie zur Detektion venöser Thromben im Tiermodell. Fortschr Röntgenstr 1999; 170: 316-321
29. Leu HJ, Feigl W, Susani M et al. Differentiation of mononuclear blood cells into macrophages, fibroblasts and endothelial cells in thrombus organization. Exp Cell Biol 1988; 56: 201-210
30. Murphy RE, Moody AR, Morgan PS et al. Prevalence of complicated carotid atheroma as detected by magnetic resonance direct thrombus imaging in patients with suspected carotid artery stenosis and previous acute cerebral ischemia. Circulation 2003; 107: 3053-3058