Evaluation of analgesia provided by the administration of epidural ketamine in dogs with a chemically induced synovitis

Veterinary Anaesthesia and Analgesia

Volumn 32, Issue 1, 2005, Pages 30-39

  Hamilton, Stephanie M ^a,b   Johnston, Spencer A ^a   Broadstone, Richard V ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Analgesia; Epidural; Force platform; Ketamine; Synovitis

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

ANALGESIC AGENT; KETAMINE;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOG; EPIDURAL ANESTHESIA; FEMALE; HINDLIMB; MALE; PAIN ASSESSMENT; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SYNOVITIS; TREATMENT OUTCOME;

ANALGESIA, EPIDURAL; ANALGESICS; ANIMALS; DOGS; FEMALE; KETAMINE; MALE; PAIN MEASUREMENT; STIFLE; SYNOVITIS; TREATMENT OUTCOME;

EID: 14944372101     PISSN: 14672987     EISSN: 14672995     Source Type: Journal    
DOI: 10.1111/j.1467-2995.2004.00171.x     Document Type: Article

References (35)

1. Amarpal HP, Aithal HP, Singh GR et al. (1999) Preemptive effects of epidural ketamine for analgesia in dogs. Indian Vet J 76, 300-303.
2. Beltrutti DP, Trompeo AC, Di Santo S (1999) The epidural and intrathecal administration of ketamine. Curr Rev Pain 3, 458-72.
3. Borgbjerg FM, Svensson BA, Frigast C et al. (1994) Histopathology after repeated intrathecal injections of preservative-free ketamine in the rabbit: a light and electron microscopic examination. Anesth Analg 79, 105-111.
4. Burton AW. Lee DH, Saab C et al. (1999) Preemptive intrathecal ketamine injection produces a long-lasting decrease in neuropathic pain behaviors in a rat model. Reg Anesth Pain Med 24. 208-213.
5. Coderre TJ, Katz J, Vaccarino AL et al. (1993) Contribution of central neuroplasticity to pathological pain: a review of clinical and experimental evidence. Pain 52, 259-285.
6. Crisp T, Perrotti JM, Smith DL (1991) The local monoaminergic dependency of spinal ketamine. Eur J Pharmacol 194, 167-172.
7. Cross AR, Budsberg SC, Keefe TJ (1997) Kinetic gait analysis of meloxicam efficacy in a sodium urate-induced synovitis model in dogs. Am J Vet Res 58, 626-631.
8. Doherty TJ, Geiser DR, Rohrbach BW (1997) The effect of high volume epidural morphine, ketamine, and butorphanol on halothane minimum alveolar concentration in ponies. Equine Vet J 29, 370-373.
9. Fam AG, Schumacher HR (1988) Crystal-induced joint inflammation. In: CRC Handbook of Animal Models for the Rheumatic Diseases. Greenwald RA. Diamond HS, (eds). CRC Press, Boca Raton, FL, USA, pp. 99-125.
10. Finck AD, Ngai SH (1982) Opiate receptor mediation of ketamine analgesia. Anesthesiology 56, 291-297.
11. Forman LJ (1999) NMDA receptor antagonism produces antinoception which is partially mediated by brain opioids and dopamine. Life Sci 64, 1877-1887.
12. Gomez de Segura IA, De Rossi R, Santos M et al. (1998) Epidural injection of ketamine for perineal analgesia in the horse. Vet Surg 27, 384-391.
13. Guirimand F, Dupont X, Brasseur L et al. (2000) The effects of ketamine on the temporal summation (wind-up) of the RTTT nociceptive flexion reflex and pain in humans. Anesth Analg 90, 408-414.
14. Hellyer PW, Gaynor JS (1998) How I treat postsurgical pain in dogs and cats. Compend Contin Educ Pract Vet 20, 140-153.
15. Hustveit O, Maurset A, Oye I (1995) Interaction of the chiral forms of ketamine with opioid, phencyclidine, sigma and muscarinic receptors. Pharmacol Toxicol 77, 355-359.
16. Jones MW. McClean M. Parsons CG et al. (2001) The in vivo relevance of the varied channel-blocking properties of uncompetitive NMDA antagonists: tests on spinal neurones. Neuropharmacology 41, 50-61.
17. Kristensen JD, Svensson BA, Gordh T (1992) The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans. Pain 51, 249-253.
18. Lament LA, Tranquilli WJ, Grimm KA (2000) Physiology of pain. Vet Clin North Am Small Anim Pract 30, 703-728.
19. Liu H-T, Hollmann MW, Liu W-H et al. (2001) Modulation of the NMDA receptor function by ketamine and magnesium: part I. Anesth Analg 92, 1173-1181.
20. Lodge D, Johnson KM (1990) Noncompetitive excitatory amino acid receptor antagonists. Trends Pharmacol Sci 11, 81-86.
21. Martin DD, Tranquilli WJ, Olson WA et al. (1996) Analgesic action of epidural ketamine injection in isoflurane-anesthetized dogs. Vet Surg 25, 184.
22. Millis DL, Weigel JP, Moyers T et al. (2002) The effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by a chemical synovitis in dogs. Compend Contin Educ Pract Vet 24, 7-18.
23. Pedraz JL. Lanao JM. Calvo MB et al. (1987) Pharmacokinetic and clinical evaluation of ketamine administered by i.v. & epidural routes. Int J Clin Pharmacol Ther Toxicol 25, 77-80.
24. Redua MA, Valadao CAA, Duque JC (2002) The preemptive effect of epidural ketamine on wound sensitivity in horses tested by using von Frey filaments. Vet Anaesth Analg 29, 200-206.
25. Rumph PF, Kincaid SA, Baird DK et al. (1993) Vertical ground reaction force distribution during experimentally induced acute synovitis in dogs. Am J Vet Res 54, 365-369.
26. Scheller M, Bufler J, Hertle I et al. (1996) Ketamine blocks currents through mammalian nicotinic acetylcholine receptor channels by interaction with both the open and the closed state. Anesth Analg 83, 830-836.
27. Schiltz C, Liote F, Prudhommeaux F et al. (2002) Monosodium urate monohydrate crystal-induced inflammation in vivo: quantitative histomorphometric analysis of cellular events. Arthritis Rheum 46, 1643-1650.
28. Schumacher HR, Phelps P, Agudelo CA (1974) Urate crystal induced inflammation in dog joints: sequence of synovial changes. J Rheumatol 1, 102-113.
29. Slingsby LS. Waterman-Pearson AE (2000) The postoperative analgesic effects of ketamine after canine ovariohysterectomy - a comparison between pre- or post-operative administration. Res Vet Sci 69, 147-152.
30. Stotz M, Oehen H-P, Gerber H (1999) Histological findings after long-term infusion of intrathecal ketamine for chronic pain: a case report. J Pain Symptom Manage 18, 223-228.
31. Torske KE. Dyson DH (2000) Epidural analgesia and anesthesia. Vet Clin North Am Small Anim Pract 30, 8 59-874.
32. Wagner AE, Walton JA, Hellyer PW et al. (2002) Use of low doses of ketamine administered by constant rate infusion as an adjunct for postoperative analgesia in dogs. J Am Vet Med Assoc 221, 72-75.
33. Woolf CJ, Chong MS (1993) Preemptive analgesia - treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 77, 362-379.
34. Woolf CJ, Thompson SWN (1991) The induction and maintenance of central sensitization is dependent on N-methyl-D aspartate acid receptor activation: implications for the treatment of post-injury pain hypersensitivity states. Pain 44, 293-299.
35. Yaksh TL (1996) Epidural ketamine: a useful, mechanistically novel adjuvant for epidural morphine? Reg Anesth 21, 508-513.