HMGA molecules in neuroblastic tumors

Annals of the New York Academy of Sciences

Volumn 1028, Issue , 2004, Pages 122-132

  Cerignoli, F ^a   Ambrosi, C ^a   Mellone, M ^a   Massimi, I ^c   Di Marcotullio, Lucia ^a   Gulino, A ^a,b   Giannini, Giuseppe ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

^c Policlinico Umberto I ^*

Author keywords

HMGA; Neuroblastic tumors; Retinoic acid

Indexed keywords

DNA; HIGH MOBILITY GROUP A PROTEIN; RETINOIC ACID;

ADRENAL GLAND; AMINO ACID SEQUENCE; CELL GROWTH; CONFERENCE PAPER; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NEUROBLASTOMA; NEUROBLASTOMA CELL; NORTHERN BLOTTING; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

EID: 14944361858     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1322.013     Document Type: Conference Paper

References (35)

1. GROSSCHEDL, R., K. GIESE & J. PAGEL. 1994. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10: 94-100.
2. JOHNSON, K.R., D.A. LEHN & R. REEVES. 1989. Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-Y. Mol. Cell. Biol, 9: 2114-2123.
3. FRIEDMANN, M. et al. 1993. Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene. Nucleic Acids Res. 21: 4259-4267.
4. SCHOENMAKERS, E.F. et al. 1995. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat. Genet, 10: 436-444.
5. ISHWAD, C.S. et al. 1997. The high mobility group I-C gene (HMGI-C): polymorphism and genetic localization. Hum. Genet. 99: 103-105.
6. SOLOMON, M.J., F. STRAUSS & A. VARSHAVSKY. 1986. A mammalian high mobility group protein recognizes any stretch of six A.T base pairs in duplex DNA. Proc. Natl. Acad. Sci. USA 83: 1276-1280.
7. REEVES, R., D.D. EDBERG & Y. LI. 2001. Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells. Mol. Cell. Biol. 21: 575-594.
8. YIE, J. et al. 1999. The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome. EMBO J. 18: 3074-3089.
9. ZHOU, X. et al. 1995. Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C. Nature 376: 771-774.
10. BATTISTA, S. et al. 1999. The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis. Cancer Res. 59: 4793-4797.
11. ARLOTTA, P. et al. 2000. Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. J. Biol. Chem. 275: 14394-14400.
12. MELILLO, R.M. et al. 2001. Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation. Mol. Cell. Biol. 21: 2485-2495.
13. TALLINI, G. & P. DAL CIN. 1999. HMGI(Y) and HMGI-C dysregulation: a common occurrence in human tumors. Adv. Anat. Pathol. 6: 237-246.
14. CHIAPPETTA, G. et al. 1998. Detection of high mobility group I HMGI(Y) protein in the diagnosis of thyroid tumors: HMGI(Y) expression represents a potential diagnostic indicator of carcinoma. Cancer Res. 58: 4193-4198.
15. ABE, N. et al. 1999. Determination of high mobility group I(Y) expression level in colorectal neoplasias: a potential diagnostic marker. Cancer Res. 59: 1169-1174.
16. TAMIMI, Y. et al. 1996. A retrospective study of high mobility group protein I(Y) as progression marker for prostate cancer determined by in situ hybridization. Br. J. Cancer 74: 573-578.
17. WOOD, L.J. et al. 2000. The oncogenic properties of the HMG-I gene family. Cancer Res. 60: 4256-4261.
18. WOOD, L.J. et al. 2000. HMG-I/Y, a new c-Myc target gene and potential oncogene. Mol. Cell. Biol. 20: 5490-5502.
19. SCALA, S. et al. 2000. Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias. Proc. Natl. Acad. Sci. USA 97: 4256-4261.
20. GIANNINI, G. et al. 2001. EGF regulates a complex pattern of gene expression and represses smooth muscle differentiation during the neurotypic conversion of the neural-crest-derived TC-IS cell line. Exp. Cell Res. 264: 353-362.
21. BRODEUR, G.M. 2003. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer 3: 203-16.
22. ABEMAYOR, E. & N. SIDELL. 1989. Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiation. Environ. Health Perspect. 80: 3-15.
23. THIELE, C.J., C.P. REYNOLDS & M.A. ISRAEL. 1985. Decreased expression of N-myc precedes retinoic acid induced morphological differentiation of human neuroblastoma. Nature 313: 404-406.
24. KAPLAN, D.R. et al. 1993. Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Neuron 11: 321-331.
25. NAKAGAWARA, A. & G.M. BRODEUR. 1997. Role of neurotrophins and their receptors in human neuroblastomas: a primary culture study. Eur. J. Cancer 33: 2050-2053.
26. LUCARELLI, E., D.R. KAPLAN & C.J. THIELE. 1995. Selective regulation of TrkA and TrkB receptors by retinoic acid and interferon-gamma in human neuroblastoma cell lines. J. Biol. Chem. 270: 24725-24731.
27. MATSUO, T. & C.J. THIELE. 1998. p27Kip1: a key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line. Oncogene 16: 3337-3343.
28. MATTHAY, K.K. et al. 1999. Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group. N. Engl. J. Med. 341: 1165-1173.
29. GIANNINI, G. et al. 1997. Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells. J. Biol. Chem. 272: 26693-26701.
30. CERIGNOLI, F. et al. 2002. retSDR1, a short-chain retinol dehydrogenase/reductase, is etinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. Cancer Res. 62: 1196-1204.
31. GIANNINI, G. et al. 1999. HMGI(Y) and HMGI-C genes are expressed in neuroblastoma cell lines and tumors and affect retinoic acid responsiveness. Cancer Res. 59: 2484-2492.
32. GIANNINI, G. et al. 2000. Expression of the HMGI(Y) gene products in human neuroblastic tumours correlates with differentiation status. Br. J. Cancer 83: 1503-1509.
33. REEVES, R., W.J. LEONARD & M.S. NISSEN. 2000. Binding of HMG-I(Y) imparts architectural specificity to a positioned nucleosome on the promoter of the human interleukin-2 receptor alpha gene. Mol. Cell. Biol. 20: 4666-4679.
34. VALLONE, D. et al. 1997. Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product. EMBO J. 16:5310-5321.
35. SCHWAB, M. et al. 2003. Neuroblastoma: biology and molecular and chromosoma pathology. Lancet Oncol. 4: 472-480.