Adjuvant prednisone therapy in pharyngitis: A randomised controlled trial from general practice

British Journal of General Practice

Volumn 55, Issue 512, 2005, Pages 218-221

  Kiderman, Alexander ^a   Yaphe, John ^c,d   Bregman, Joseph ^b   Zemel, Tamar ^b   Furst, Arthur L ^a  

^a HEBREW UNIVERSITY   (Israel)

^b CLALIT HEALTH SERVICES   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d RABIN MEDICAL CENTER   (Israel)

Author keywords

Corticosteroids; Pharyngitis; Placebos; Randomised controlled trials

Indexed keywords

AMOXICILLIN; ERYTHROMYCIN; PENICILLIN V POTASSIUM; PLACEBO; PREDNISONE; SHORT ACTING DRUG;

ABSENTEEISM; ADJUVANT THERAPY; ADULT; AGED; ANALGESIA; ARTICLE; BACTERIAL INFECTION; BACTERIUM CULTURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE DURATION; DOSE TIME EFFECT RELATION; DRUG DOSE REGIMEN; DRUG EFFICACY; DYSPHAGIA; EXPERIENCE; FEMALE; FEVER; GENERAL PRACTICE; HUMAN; ISRAEL; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OUTCOMES RESEARCH; PAIN ASSESSMENT; PHARYNGITIS; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; SYMPTOMATOLOGY; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; CHEMOTHERAPY, ADJUVANT; DOSE-RESPONSE RELATIONSHIP, DRUG; FAMILY PRACTICE; FOLLOW-UP STUDIES; HUMANS; ISRAEL; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; PHARYNGITIS; PREDNISONE; RECURRENCE; TREATMENT OUTCOME;

EID: 14944355895     PISSN: 09601643     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Del Mar C, Glasiou P. Upper respiratory tract infection. Clin Evid 2002; 7: 1391-1399.
2. Del Mar CB, Glasziou PP, Spinks AB. Antibiotics for sore throat. Cochrane Database Syst Rev 2000; (4): CD000023.
3. Schuh S, Coates AL, Binnie R, et al. Efficacy of oral dexamethasone in outpatients with acute bronchiolitis. J Pediatr 2002; 140: 27-32.
4. Cruz MN, Stewart G, Rosenberg N. Use of dexamethasone in the outpatient management of acute laryngotracheitis. Pediatrics 1995; 96: 220-223.
5. Marvez-Valls EG, Stuckey A, Ernst AA. A randomized clinical trial of oral versus intramuscular delivery of steroids in acute exudative pharyngitis. Acad Emerg Med 2002; 9: 9-14.
6. O'Brien JF, Meade JL, Falk JL. Dexamethasone as adjuvant therapy for severe acute pharyngitis. Ann Emerg Med 1993; 22: 212-215.
7. Marvez-Valls EG, Ernst AA, Gray J, Johnson WD The role of betamethasone in the treatment of acute exudative pharyngitis. Acad Emerg Med 1998; 5: 567-572.
8. Wei JL, Kasperbauer JL, Weaver AL, Boggust AJ. Efficacy of single-dose dexamethasone as adjuvant therapy for acute pharyngitis. Laryngoscope 2002; 112: 87-93.
9. Bulloch B, Kabani A, Tenenbein M. Oral dexamethasone for the treatment of pain in children with acute pharyngitis: a randomized, double-blind, placebo-controlled trial. Ann Emerg Med 2003; 41: 601-608.
10. Dupont WD, Plummer WD. Power and sample size calculations: a review and computer program. Controlled Clin Trials 1990; 11: 116-128.
11. Steward DL, Welge JA, Myer CM. Do steroids reduce morbidity of tonsillectomy? Meta-analysis of randomized trials. Laryngoscope 2001; 111: 1712-1718.